Jing‐Yang Huang
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View article: Association of tirzepatide and the risk of suicide in a real-world cohort
Association of tirzepatide and the risk of suicide in a real-world cohort Open
Background Glucagon-like peptide-1 (GLP-1) receptor agonists, including tirzepatide, are increasingly prescribed for obesity and type 2 diabetes mellitus. Amid safety concerns raised by regulatory agencies regarding potential associations …
View article: The Effect of Preoperative Aqueous Total Antioxidant Capacity on the Postoperative Complications of Cataract Surgery
The Effect of Preoperative Aqueous Total Antioxidant Capacity on the Postoperative Complications of Cataract Surgery Open
A low TAC status is associated with a higher incidence of postoperative corneal edema and ocular hypertension.
View article: Risk of acute kidney injury and mortality in patients vaccinated against COVID-19
Risk of acute kidney injury and mortality in patients vaccinated against COVID-19 Open
Several types of vaccines have been developed to manage the coronavirus disease 2019 (COVID-19) pandemic. Although COVID-19 vaccines have demonstrated reasonable efficacy, cases of cardiac, vascular and renal complications have been observ…
View article: Reduced Risk of Sleep Disturbance and Obstructive Sleep Apnea Following Joint Replacement in Osteoarthritis Patients
Reduced Risk of Sleep Disturbance and Obstructive Sleep Apnea Following Joint Replacement in Osteoarthritis Patients Open
Osteoarthritis (OA) is a prevalent condition characterized by inflammatory responses, and joint replacement surgery has been widely utilized for its management over the past several decades. Sleep disorders such as sleep disturbance and ob…
View article: Glaucoma Risk of Serotonin-norepinephrine Reuptake Inhibitors (SNRIs) and Gabapentinoids in Fibromyalgia Patients
Glaucoma Risk of Serotonin-norepinephrine Reuptake Inhibitors (SNRIs) and Gabapentinoids in Fibromyalgia Patients Open
Objectives To evaluate the association between glaucoma risk and the use of serotonin-norepinephrine reuptake inhibitors (SNRIs) and gabapentinoids in patients with fibromyalgia (FM). Methods We conducted this retrospective cohort study by…
View article: Myopic Control Using Defocus-Incorporated Multiple Segments Spectacle Lenses Plus Low-Concentration Atropine in Patients With Fast Myopia Progression: A Retrospective Cohort Study
Myopic Control Using Defocus-Incorporated Multiple Segments Spectacle Lenses Plus Low-Concentration Atropine in Patients With Fast Myopia Progression: A Retrospective Cohort Study Open
Purpose The aim of this study is to evaluate the myopic control effect between defocus-incorporated multiple segments (DIMS) spectacle lenses plus 0.01% atropine (ATR), and 0.125% ATR, for patients with fast myopia progression. Methods A r…
View article: Impact of prolonged and short QT intervals on immediate risks of newly diagnosed arrhythmias and mortality: A retrospective study
Impact of prolonged and short QT intervals on immediate risks of newly diagnosed arrhythmias and mortality: A retrospective study Open
The relationship between corrected QT (QTc) intervals and short-term clinical outcomes remains insufficiently investigated. This study examined correlations between QTc intervals and risks of arrhythmia or mortality over a 3-month follow-u…
View article: COVID-19 Vaccination Reduces Lower Limb Amputation Rates and Mortality Rate in Patients with Pre-Existing Peripheral Vascular Disease Based on TriNetX Database
COVID-19 Vaccination Reduces Lower Limb Amputation Rates and Mortality Rate in Patients with Pre-Existing Peripheral Vascular Disease Based on TriNetX Database Open
Background: Unvaccinated individuals with peripheral arterial occlusive disease (PAOD) are more likely to develop acute limb ischemia (ALI) following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We assessed the p…
View article: The Effect of Hyaluronic Acid-contained Artificial Tear on Refractive Accuracy of Cataract Surgery in Dry Eye Population: A Retrospective Cohort Study
The Effect of Hyaluronic Acid-contained Artificial Tear on Refractive Accuracy of Cataract Surgery in Dry Eye Population: A Retrospective Cohort Study Open
Perioperative use of HA-containing artificial tears is associated with improved refractive accuracy following cataract surgery in patients with DED.
View article: Postoperative Decline in Antioxidant Concentrations in Aqueous Humor: Comparison Between Femtosecond Laser-assisted Cataract Surgery and Conventional Cataract Surgery
Postoperative Decline in Antioxidant Concentrations in Aqueous Humor: Comparison Between Femtosecond Laser-assisted Cataract Surgery and Conventional Cataract Surgery Open
Patients with high myopia and dense cataract may consider FLACS to reduce the possibility of oxidative stress-related postoperative complications.
View article: The Association of Insomnia and the Subsequent Cerebrovascular Accident in the Hypertension Population
The Association of Insomnia and the Subsequent Cerebrovascular Accident in the Hypertension Population Open
In individuals with hypertension, the presence of insomnia is associated with a significantly higher risk of both ischemic and hemorrhagic stroke.
View article: The Myopic Control Effect of Defocus Incorporated Multiple Segments’ Spectacle Lens With Atropine in High Myopia Population
The Myopic Control Effect of Defocus Incorporated Multiple Segments’ Spectacle Lens With Atropine in High Myopia Population Open
The combined ATR plus DIMS spectacle lenses was more effective in slowing myopia progression than ATR monotherapy in children with high myopia. This combined approach may be a preferable strategy for managing high-risk pediatric myopia.
View article: The Correlation Between Aortic Stenosis and the Incidence of Subsequent Ocular Surface Diseases
The Correlation Between Aortic Stenosis and the Incidence of Subsequent Ocular Surface Diseases Open
The presence of AS associates with a higher risk of subsequent DED and superficial keratopathy development, which positively relate to the duration of AS.
View article: Beta-Blocker Use and Risk of Hip Arthroplasty in Osteoarthritis: A Retrospective Electronic Health Record Study
Beta-Blocker Use and Risk of Hip Arthroplasty in Osteoarthritis: A Retrospective Electronic Health Record Study Open
Objectives: This study aimed to determine whether prior use of a beta blocker (BB) is associated with the three-year risk of total hip arthroplasty after being diagnosed with osteoarthritis of the hip and compare risks across BB subtypes. …
View article: Association Between Melatonin Use and Cataract Risk: A Target Trial Emulation Retrospective Cohort Study
Association Between Melatonin Use and Cataract Risk: A Target Trial Emulation Retrospective Cohort Study Open
Oxidative stress has been shown to play an important role in the development of cataracts. Melatonin is an endogenous hormone that has been proposed to have a protective effect against oxidative stress; however, its association with the ri…
View article: Interaction of ALDH2 and ALDH1A single-nucleotide polymorphisms with alcohol consumption and impact on osteoporosis risk
Interaction of ALDH2 and ALDH1A single-nucleotide polymorphisms with alcohol consumption and impact on osteoporosis risk Open
The ALDH2 rs75162023 C > T variant may increase osteoporosis risk in individuals with chronic alcohol exposure. Reducing alcohol intake may benefit from avoiding alcohol to reduce osteoporosis risk in genetically susceptible individuals.
View article: SARS-CoV-2 Vaccination Reduces Lower Limb Amputation Rates and Motality Rate in Patients with Preexisting Peripheral Vascular Disease by TriNetX Database
SARS-CoV-2 Vaccination Reduces Lower Limb Amputation Rates and Motality Rate in Patients with Preexisting Peripheral Vascular Disease by TriNetX Database Open
Backgound: Unvaccinated individuals with peripheral arterial occlusive disease (PAOD) are more likely to develop acute limb ischemia (ALI) following COVID-19 infection. Our assessed the protective effect of the COVID-19 vaccine in preventi…
View article: The application of hyaluronic acid-containing artificial tears on the ocular surface of children receiving orthokeratology contact lens treatment
The application of hyaluronic acid-containing artificial tears on the ocular surface of children receiving orthokeratology contact lens treatment Open
Purpose: The purpose of this study was to compare the effects of the application of hyaluronic acid (HA)-containing artificial tears and non-HA artificial tears on the ocular surface of children receiving orthokeratology contact lens treat…
View article: Comparative Effects of Tirzepatide and Semaglutide on Asthma-Related Complications: A Target Trial Emulation Using the TriNetX Networks
Comparative Effects of Tirzepatide and Semaglutide on Asthma-Related Complications: A Target Trial Emulation Using the TriNetX Networks Open
Objective Tirzepatide and semaglutide are widely administered for individuals with type 2 diabetes mellitus (T2DM) or obesity. In this study, we aimed to evaluate the overall impact of these medications on patients with asthma. Patients an…
View article: The Correlation Between Aortic Stenosis and the Subsequent Incidence of Optic Neuropathy: A Population-based Cohort Study
The Correlation Between Aortic Stenosis and the Subsequent Incidence of Optic Neuropathy: A Population-based Cohort Study Open
The existence of AS correlates to higher risk of developing glaucoma and ischemic optic neuropathy.
View article: The Effect of Preoperative Dry Eye Disease on the Outcome of Second (Visumax 800) Generation Keratorefractive Lenticule Extraction Surgery
The Effect of Preoperative Dry Eye Disease on the Outcome of Second (Visumax 800) Generation Keratorefractive Lenticule Extraction Surgery Open
The presence of preoperative DED is associated with worse postoperative UDVA recovery and refraction of second generation KLEx surgery, which can be prevented by preoperative AT application.
View article: Ovarian Cancer and the Risk of Cataract Episodes: A Nationwide Cohort Study
Ovarian Cancer and the Risk of Cataract Episodes: A Nationwide Cohort Study Open
Ovarian cancer is associated with a marginally higher incidence of cataracts and cataract surgery.
View article: Superior cardiovascular protection with GLP-1 RAs over SGLT2 inhibitors in DM and HFpEF: A propensity score matching study
Superior cardiovascular protection with GLP-1 RAs over SGLT2 inhibitors in DM and HFpEF: A propensity score matching study Open
Background Heart failure with preserved ejection fraction (HFpEF) and diabetes mellitus (DM) are interrelated conditions associated with high morbidity and mortality. This study compared the cardiovascular protective effects of glucagon-li…
View article: Risk of neurodevelopmental disorders in the offspring of mothers with a history of endometriosis in Taiwanese women
Risk of neurodevelopmental disorders in the offspring of mothers with a history of endometriosis in Taiwanese women Open
Several neurodevelopmental disorders have been linked to early life immune activation and inflammation, including developmental delay, cerebral palsy, intellectual disabilities, and other neurodevelopmental and psychiatric disorders. Certa…
View article: Comparative effectiveness of dual-focus contact lenses and DIMS spectacle lenses for myopia control in patients with low astigmatism: a retrospective study
Comparative effectiveness of dual-focus contact lenses and DIMS spectacle lenses for myopia control in patients with low astigmatism: a retrospective study Open
Purpose This study aimed to evaluate and compare the effectiveness of dual-focus contact lenses (DFCL) and defocus incorporated multiple segment (DIMS) spectacle lenses in controlling myopia progression in patients with low astigmatism. Me…
View article: Association between SGLT-2 inhibitors and suicide risk in type 2 diabetes and bipolar: a real-world cohort study
Association between SGLT-2 inhibitors and suicide risk in type 2 diabetes and bipolar: a real-world cohort study Open
Background Individuals with bipolar disorder face a significantly elevated suicide risk, and comorbid type 2 diabetes mellitus (T2DM) further complicates their psychiatric and medical outcomes. Sodium–glucose co-transporter-2 inhibitors (S…
View article: The Daily and Two-Day Usage of Low-Dose Atropine on Myopic Control in a Low-Myopia Population
The Daily and Two-Day Usage of Low-Dose Atropine on Myopic Control in a Low-Myopia Population Open
Objectives: The aim of this study was to evaluate the effectiveness of using low-dose atropine (ATR) at different instillation frequencies on myopia control in a low-myopia population. Methods: A retrospective cohort study was conducted, a…
View article: The severity of coronary heart disease and the incidence and severity of following obstructive sleep apnea: a population-based cohort study
The severity of coronary heart disease and the incidence and severity of following obstructive sleep apnea: a population-based cohort study Open
Obstructive sleep apnea (OSA) is characterized by pharyngeal collapse, hypoxia, and hypercapnia. However, the impact of coronary heart disease (CHD) severity on OSA development has been rarely explored. This study aimed to evaluate the cor…
View article: The effect of defocus incorporated multiple segment spectacles’ lenses combined with different concentrations atropine for myopia control
The effect of defocus incorporated multiple segment spectacles’ lenses combined with different concentrations atropine for myopia control Open
We aim to evaluate the myopia control effect of defocus incorporated multiple segments' (DIMS) spectacle lens in combination with different concentrations of atropine (ATR). A retrospective cohort study was conducted and DIMS users were ca…