Majid S. Jabir
YOU?
Author Swipe
View article: Integrated Synthesis, Characterization, and Bioactivity Profiling of Imide Derivatives: Insights from Molecular Docking Analysis
Integrated Synthesis, Characterization, and Bioactivity Profiling of Imide Derivatives: Insights from Molecular Docking Analysis Open
Heterocyclic compounds are by far the most significant traditional category of organic chemistry and have enormous biological and industrial implications. In this study, a chalcone intermediate was synthesized and used to synthesize imide …
View article: Association of IL-1β rs16944 polymorphisms and the subsequent level of IL-1β in type 2 diabetes mellitus: Case-control study
Association of IL-1β rs16944 polymorphisms and the subsequent level of IL-1β in type 2 diabetes mellitus: Case-control study Open
Strong relationships exist between immune factors and hyperglycemia, particularly proinflammatory factors such as interleukin (IL)-1β protein levels and genetics, which significantly correlate with the development of type 2 diabetes mellit…
View article: Antibacterial and Anticancer Properties of Zinc Oxide Nanoparticles: A Review of Current Advances and Future Directions
Antibacterial and Anticancer Properties of Zinc Oxide Nanoparticles: A Review of Current Advances and Future Directions Open
Zinc oxide Nanoparticles (ZnO-NPs) have a promising potential in antibacterial and anticancer treatments because of their ease of production, low toxicity, and versatility in application. This review encompasses recently developed synthesi…
View article: Molecular docking study and pharmacokinetic insights of rifampicin in pure and capsule dosage forms
Molecular docking study and pharmacokinetic insights of rifampicin in pure and capsule dosage forms Open
To detect the amount of rifampicin in bulk and medicinal dosage formulations, an accurate and cost-effective UV spectrophotometric technique has been developed using the area under the peak to estimate the presence of rifampicin. This rang…
View article: Mutation Analysis of Advanced Non-Small Cell Lung Cancer: A Retrospective Observational Study from South India
Mutation Analysis of Advanced Non-Small Cell Lung Cancer: A Retrospective Observational Study from South India Open
Lung cancer is a leading cause of cancer-related mortality worldwide, with non-small cell lung cancer (NSCLC) being the predominant type. Comprehensive genomic profiling plays a crucial role in identifying actionable mutations to guide per…
View article: Metastatic Solitary Fibrous Tumor of Parapharyngeal Region: A Case Report with Review of Literature
Metastatic Solitary Fibrous Tumor of Parapharyngeal Region: A Case Report with Review of Literature Open
Solitary fibrous tumor (SFT) is a rare fibroblastic mesenchymal neoplasm with a low metastatic potential. The parapharyngeal area in the head and neck is one of the rarest subsites. Surgical excision remains the standard of care. The local…
View article: Pharmaceutical properties of novel 3-((diisopropylamino)methyl)-5-(4-((4-(dimethylamino) benzylidene) imino) phenyl)-1,3,4-oxadiazole-2(3 H)-thione
Pharmaceutical properties of novel 3-((diisopropylamino)methyl)-5-(4-((4-(dimethylamino) benzylidene) imino) phenyl)-1,3,4-oxadiazole-2(3 H)-thione Open
The synthesis of novel chemical compounds is crucial for developing new pharmaceuticals and antimicrobial agents. The Mannich reaction, involving Maunch bases known as carrier beta-amino-ketone molecules, is significant for producing nitro…
View article: Corrigendum: Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties
Corrigendum: Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties Open
[This corrects the article DOI: 10.3389/fphar.2024.1511627.].
View article: A Low‐Fouling Electrochemical Immunosensor Based On Metal–Organic Framework and Ternary Metal Oxide Nanomaterials Using Dual Signal Amplification Strategy for Sensitive Detection of Prostate‐Specific Antigen (PSA) in Patient Samples
A Low‐Fouling Electrochemical Immunosensor Based On Metal–Organic Framework and Ternary Metal Oxide Nanomaterials Using Dual Signal Amplification Strategy for Sensitive Detection of Prostate‐Specific Antigen (PSA) in Patient Samples Open
A label‐free electrochemical immunosensor based on the zeolitic imidazolate framework‐8 (ZIF8)/bismuth ferrite (BFO) nanocomposite was fabricated for the specific and sensitive quantification of prostate‐specific antigen (PSA). The ZIF8‐BF…
View article: Risk of suicide, suicide attempt, and suicidal ideation among people with vitamin D deficiency: a systematic review and meta-analysis
Risk of suicide, suicide attempt, and suicidal ideation among people with vitamin D deficiency: a systematic review and meta-analysis Open
The results of this meta-analysis indicated that vitamin D levels are lower among patients with SBs. These findings can inform suicide prevention programs, particularly for target groups experiencing significant vitamin D deficiency.
View article: The role of autophagy in Graves disease: knowns and unknowns
The role of autophagy in Graves disease: knowns and unknowns Open
Graves disease (GD), an autoimmune disease affects the thyroid gland, results in hyperthyroidisms and goiter. The main cause of GD is not clearly defined; however, stimulating autoantibodies for thyroid stimulating hormone receptor (TSHR) …
View article: Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties
Synthesis, characterization, and computational evaluation of some synthesized xanthone derivatives: focus on kinase target network and biomedical properties Open
Background Xanthones are dubbed as putative lead-like molecules for cancer drug design and discovery. This study was aimed at the synthesis, characterization, and in silico target fishing of novel xanthone derivatives. Methods The products…
View article: Biogenic synthesized selenium nanoparticles combined chitosan nanoparticles controlled lung cancer growth <i>via</i> ROS generation and mitochondrial damage pathway
Biogenic synthesized selenium nanoparticles combined chitosan nanoparticles controlled lung cancer growth <i>via</i> ROS generation and mitochondrial damage pathway Open
The green synthesis approach has drawn a lot of interest as an environmentally friendly and sustainable acceptable means of producing a diverse range of nanoparticles (NPs). This piece described a rapid approach for synthesizing selenium n…
View article: A Computational Effort To Untangling Anti-SARS-CoV-2 Effects Of Oleanolic Acid Analogues
A Computational Effort To Untangling Anti-SARS-CoV-2 Effects Of Oleanolic Acid Analogues Open
Considering the current global pandemic and the urgent need to introduce novel drug candidates against severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), we reported at least four antipyretic recipes of Kurdish ethnomedicine wh…
View article: Therapeutic Challenges in the Management of Collecting Duct Carcinoma of the Kidney: A Case Report with Review of Literature
Therapeutic Challenges in the Management of Collecting Duct Carcinoma of the Kidney: A Case Report with Review of Literature Open
Collecting duct carcinoma (CDC) of the kidney is a rare type of renal cell carcinoma. It is an aggressive tumor with a poor prognosis and limited treatment options. A 67-year-old man, during evaluation for hematuria, loss of appetite and w…
View article: Insights into the pharmaceutical properties and in silico study of novel hydrazone derivatives
Insights into the pharmaceutical properties and in silico study of novel hydrazone derivatives Open
It has been established that the Hydrazone derivatives have important pharmacological effects. In the first step, hydrazine (NH2NH2) reacts with a compound containing a carbonyl group (C = O) in the presence of ethanol and heat, leading to…
View article: Topical Application of Dipyridamole and Roflumilast Combination Nanoparticles Loaded Nanoemulgel for the Treatment of Psoriasis in Rats
Topical Application of Dipyridamole and Roflumilast Combination Nanoparticles Loaded Nanoemulgel for the Treatment of Psoriasis in Rats Open
The new DR-NEG's topical combination administration showed better anti-inflammatory, tissue healing, and anti-psoriatic activity than each drug alone or topical clobetasol administration; this could be attributed to the possible synergic e…
View article: Comparison of different dietary levels of iron and zinc for the enrichment of eggs in laying hens
Comparison of different dietary levels of iron and zinc for the enrichment of eggs in laying hens Open
Zinc (Zn) and iron (Fe) are necessary for structural and metabolic functions of the body like, immune competence, physical growth, reproductive function, and neurobehavioral development. The deficiency of micronutrients is a severe public …
View article: Modification of MWCNTs with Bi2WO6 nanoparticles targeting IL-1β and NLRP3 inflammasome via augmented autophagy
Modification of MWCNTs with Bi2WO6 nanoparticles targeting IL-1β and NLRP3 inflammasome via augmented autophagy Open
This study reports the facile hydrothermal synthesis of pure Bi 2 WO 6 and Bi 2 WO 6 \MWCNTs nanocomposite at specific molar ratio 1:2.5 of Bi 2 WO 6 :MWCNTs and elucidates their role in modulating the NLRP3 inflammasome pathway via autoph…
View article: 2-(Benzhydryl sulfinyl)-N-sec-butylacetamide isolated from fig fruits as a potential immune response modulator
2-(Benzhydryl sulfinyl)-N-sec-butylacetamide isolated from fig fruits as a potential immune response modulator Open
The phagocytic activities of various immune cells can be enhanced by the use of medicinal preparations that can confer physiological homeostasis through the elimination of both pathogenic material and cells experiencing apoptosis. Neverthe…
View article: Novel Eco‐Friendly Electrode: Copper Nanoparticle‐Doped MWCNTs for Green Electro‐Organic Synthesis of 1,2,3‐Triazoles With ChCl/Urea as a Solvent and Cocatalyst
Novel Eco‐Friendly Electrode: Copper Nanoparticle‐Doped MWCNTs for Green Electro‐Organic Synthesis of 1,2,3‐Triazoles With ChCl/Urea as a Solvent and Cocatalyst Open
Meticulous electrode design is pivotal in advancing greener and more sustainable electro‐organic synthesis practices. In this research, our team designed and synthesized a copper‐doped electrode on multiwalled carbon nanotubes (MWCNTs) and…