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View article: Virtual Reality in Preclinical and Clinical Education—An Insight into Current Advancements and Future Perspectives
Virtual Reality in Preclinical and Clinical Education—An Insight into Current Advancements and Future Perspectives Open
This review examines the current state of virtual reality (VR) applications in preclinical and clinical medical education, emphasizing their impact on teaching effectiveness and clinical competence. A structured literature analysis was con…
View article: From Inflammation to Malignancy: The Link Between Endometriosis and Gynecological Cancers
From Inflammation to Malignancy: The Link Between Endometriosis and Gynecological Cancers Open
Endometriosis, a chronic estrogen-dependent disease, is associated with a risk of developing gynecological cancers. The mechanisms of this association remain unclear, but emerging evidence implicates key signaling pathways, including PI3K/…
View article: Fatal Free Falls: A Clinical and Forensic Analysis of Skeletal Injury Patterns Using PMCT and Autopsy
Fatal Free Falls: A Clinical and Forensic Analysis of Skeletal Injury Patterns Using PMCT and Autopsy Open
Background: Free fatal falls (FFF) are a frequent occurrence in forensic medicine. Many variables, such as the victim’s sex, BMI, intoxication, height of the fall, and mental illness, can influence injury patterns. Previous studies identif…
View article: Fracture Patterns in Fatal Free Falls: A Systematic Review of Intrinsic and Extrinsic Risk Factors and the Role of Postmortem CT
Fracture Patterns in Fatal Free Falls: A Systematic Review of Intrinsic and Extrinsic Risk Factors and the Role of Postmortem CT Open
Background: Free fatal falls (FFF) represent a distinct form of blunt force trauma (BFT) that is frequently encountered in forensic practice. Distinguishing FFF injuries from other forms of BFT, such as motor vehicle accidents (MVAs), can …
View article: Intestinal volvulus and obstruction due to combined button battery and magnet ingestion: a medico-legal case report
Intestinal volvulus and obstruction due to combined button battery and magnet ingestion: a medico-legal case report Open
This study presents a medico-legal case study of an infant who died as a result of intestinal volvulus, a rare but severe complication secondary to the ingestion of multiple magnets and button batteries. The mutual attraction of magnets th…
View article: Micro RNA in Colorectal Cancer—Potential Diagnostic and Prognostic Markers—An Updated Review
Micro RNA in Colorectal Cancer—Potential Diagnostic and Prognostic Markers—An Updated Review Open
Colorectal cancer (CRC) is one of the deadliest and most frequently occurring cancers worldwide. Often diagnosed in advanced stages, it requires more challenging treatment. However, emerging studies highlight the possible role of microRNAs…
View article: From Pathophysiology to Innovative Therapies in Eye Diseases: A Brief Overview
From Pathophysiology to Innovative Therapies in Eye Diseases: A Brief Overview Open
Molecular imaging and precision therapies are transforming ophthalmology, enabling earlier and more accurate diagnosis and targeted treatment of sight-threatening diseases. This review focuses on age-related macular degeneration, diabetic …
View article: Management and Outcomes of Non-Missile Penetrating Brain Injury Involving the Anterior Skull Base: A Case Report and Systematic Review
Management and Outcomes of Non-Missile Penetrating Brain Injury Involving the Anterior Skull Base: A Case Report and Systematic Review Open
Introduction: Non-missile penetrating brain injury (PBI) involving the anterior skull base constitutes a rare subclass of traumatic brain injury in civilians. Management of this type of trauma is poorly described in the literature, with on…
View article: Metallomic Profiling of the Human Eye and Its Relevance to Ophthalmic Diseases
Metallomic Profiling of the Human Eye and Its Relevance to Ophthalmic Diseases Open
Levels of micro- and macroelements in the human organism change dynamically and undoubtedly remain critical for human health. Currently, much research is focused on searching for the concentrations of various metals (including toxic ones) …
View article: Trace Elements—Role in Joint Function and Impact on Joint Diseases
Trace Elements—Role in Joint Function and Impact on Joint Diseases Open
Proper joint function has a significant impact on people’s quality of life. Joints are the point of connection between two or more bones and consist of at least three elements: joint surfaces, the joint capsule, and the joint cavity. Joint…
View article: Iron in multiple sclerosis – from pathophysiology to disease progression – a narrative literature review
Iron in multiple sclerosis – from pathophysiology to disease progression – a narrative literature review Open
Multiple sclerosis (MS) is a chronic autoimmune illness characterized by demyelination and neurodegeneration, which causes physical disability and severe alterations in the neurological system, including gliosis and neuron loss. The diseas…
View article: Review of Applications of Zeolites in Dermatology: Molecular Perspectives and Translational Potentials
Review of Applications of Zeolites in Dermatology: Molecular Perspectives and Translational Potentials Open
Zeolites, microporous aluminosilicates with tuneable physicochemical properties, have garnered increasing attention in dermatology due to their antimicrobial, detoxifying, and drug delivery capabilities. This review evaluates the structura…
View article: Evidence of Organ-Specific Metal Accumulation: ICP-MS Elemental Analysis of Autopsy Tissues of Tobacco Smokers
Evidence of Organ-Specific Metal Accumulation: ICP-MS Elemental Analysis of Autopsy Tissues of Tobacco Smokers Open
Cigarette smoking exposes individuals to numerous toxic substances, including heavy metals. Smokers are at risk due to the accumulation of these substances in various tissues. Objective: To compare the concentrations of 41 elements in 11 b…
View article: Micro- and Nanoplastics as Disruptors of the Endocrine System—A Review of the Threats and Consequences Associated with Plastic Exposure
Micro- and Nanoplastics as Disruptors of the Endocrine System—A Review of the Threats and Consequences Associated with Plastic Exposure Open
Plastic overconsumption has emerged as a major environmental pollutant, with degraded micro- and nanoplastic (MNP) particles being consumed by a vast variety of species. MNPs, particles < 5 mm, contain endocrine-disrupting chemicals (EDCs)…
View article: Post-mortem evidence of microplastic bioaccumulation in human organs: insights from advanced imaging and spectroscopic analysis
Post-mortem evidence of microplastic bioaccumulation in human organs: insights from advanced imaging and spectroscopic analysis Open
Humans are chronically exposed to airborne particulate matter and environmental microplastics through food, water, and consumer products. These anthropogenic pollutants may accumulate in human tissues, but their distribution and chemical i…
View article: Articular Cartilage: Structure, Biomechanics, and the Potential of Conventional and Advanced Diagnostics
Articular Cartilage: Structure, Biomechanics, and the Potential of Conventional and Advanced Diagnostics Open
Articular cartilage (AC) plays an important role in the biomechanics of synovial joints. Its task is to enable smooth movement and transfer of mechanical loads with minimised friction. AC is characterised by unique mechanical properties re…
View article: Advances in 3D Printing Applications for Personalized Orthopedic Surgery: From Anatomical Modeling to Patient-Specific Implants
Advances in 3D Printing Applications for Personalized Orthopedic Surgery: From Anatomical Modeling to Patient-Specific Implants Open
Three-dimensional (3D) printing has gained substantial interest among scientists and surgeons over the past decade due to its broad potential in medical applications. Its clinical utility has been increasingly recognized, demonstrating pro…
View article: Changes in the distribution of elements in the liver and various brain regions in suicides from southeastern Poland
Changes in the distribution of elements in the liver and various brain regions in suicides from southeastern Poland Open
View article: Thyroid Cancer: Epidemiology, Classification, Risk Factors, Diagnostic and Prognostic Markers, and Current Treatment Strategies
Thyroid Cancer: Epidemiology, Classification, Risk Factors, Diagnostic and Prognostic Markers, and Current Treatment Strategies Open
Thyroid cancer (TC) invariably remains the most prevalent endocrine cancer in the world. Major histological forms of TC include papillary (PTC), follicular (FTC), medullary (MTC), and anaplastic thyroid carcinoma (ATC), each of which has a…
View article: Effects of Trace Elements on Endocrine Function and Pathogenesis of Thyroid Diseases—A Literature Review
Effects of Trace Elements on Endocrine Function and Pathogenesis of Thyroid Diseases—A Literature Review Open
The thyroid gland is an endocrine organ whose hormones enable the proper functioning of the organism. The normal function of this organ is influenced by internal and external factors. One of the external factors is trace elements. Trace el…
View article: Ewing sarcoma – pathomechanisms, standard treatment and new therapeutic perspectives
Ewing sarcoma – pathomechanisms, standard treatment and new therapeutic perspectives Open
Introduction: Ewing sarcoma is the second most common bone tumor among children, and due to its high malignancy 5-year survival rate for patients with primary lesions is around 70%. This number drops to merely 30% if metastases are present…
View article: Application of ophthalmoscopy in forensic medicine
Application of ophthalmoscopy in forensic medicine Open
View article: Multiple Subpial Transection for the Treatment of Landau–Kleffner Syndrome—Review of the Literature
Multiple Subpial Transection for the Treatment of Landau–Kleffner Syndrome—Review of the Literature Open
As speech-related symptoms of Landau–Kleffner syndrome (LKS) are often refractory to pharmacotherapy, and resective surgery is rarely available due to the involvement of the vital cortex, multiple subpial transection (MST) was suggested to…
View article: Association Between Serum Concentrations of (Certain) Metals and Type 2 Diabetes Mellitus
Association Between Serum Concentrations of (Certain) Metals and Type 2 Diabetes Mellitus Open
The findings regarding trace element concentrations in patients diagnosed with type 2 diabetes and healthy controls are inconsistent, and therefore, we determined to gather them in the form of a review to further indicate the need for more…
View article: Microplastics in the Human Body: Exposure, Detection, and Risk of Carcinogenesis: A State-of-the-Art Review
Microplastics in the Human Body: Exposure, Detection, and Risk of Carcinogenesis: A State-of-the-Art Review Open
Background: Humans cannot avoid plastic exposure due to its ubiquitous presence in the natural environment. The waste generated is poorly biodegradable and exists in the form of MPs, which can enter the human body primarily through the dig…
View article: Significance of Immune and Non-Immune Cell Stroma as a Microenvironment of Hepatocellular Carcinoma—From Inflammation to Hepatocellular Carcinoma Progression
Significance of Immune and Non-Immune Cell Stroma as a Microenvironment of Hepatocellular Carcinoma—From Inflammation to Hepatocellular Carcinoma Progression Open
Hepatocellular carcinoma (HCC) is the most common liver cancer as well as the most prevalent cause of death in the adult patient population with cirrhosis. The occurrence of HCC is primarily caused by chronic liver inflammation that might …
View article: Oral Microbiota and the Risk of Gastrointestinal Cancers—A Narrative Literature Review
Oral Microbiota and the Risk of Gastrointestinal Cancers—A Narrative Literature Review Open
The human body is colonized by trillions of microorganisms in a symbiotic relationship. The oral cavity represents one of the most abundant microbial habitats in our body. Advances in sequencing techniques provide a more detailed understan…
View article: Micro- and Macronutrients in Endometrial Cancer—From Metallomic Analysis to Improvements in Treatment Strategies
Micro- and Macronutrients in Endometrial Cancer—From Metallomic Analysis to Improvements in Treatment Strategies Open
Endometrial cancer is reported to be one of the most prevalent cancers of the female reproductive organs worldwide, with increasing incidence and mortality rates over the past decade. Early diagnosis is critical for effective treatment. Re…
View article: Microbiological bases of obsessive‑compulsive disorder – the role of viruses, bacteria, and parasites in the onset and progression of OCD
Microbiological bases of obsessive‑compulsive disorder – the role of viruses, bacteria, and parasites in the onset and progression of OCD Open
Obsessive‑compulsive disorder (OCD) is a current topic of discussion nowadays. OCD presents a variety of different etiologies including environmental, viral, cognitive, or genetic aspects. In this article, we focused on the possible correl…
View article: Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer’s Disease
Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer’s Disease Open
Alzheimer’s disease (AD) is characterized by, among other things, dementia and a decline in cognitive performance. In AD, dementia has neurodegenerative features and starts with mild cognitive impairment (MCI). Research indicates that apop…