Jacek Radwan
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View article: Sexual selection associated with an aggressive male phenotype reduces population size and hinders population recovery after heat stress
Sexual selection associated with an aggressive male phenotype reduces population size and hinders population recovery after heat stress Open
View article: Beyond the laboratory: the bank vole (Clethrionomys glareolus) as a novel model organism in biological research
Beyond the laboratory: the bank vole (Clethrionomys glareolus) as a novel model organism in biological research Open
View article: Interplay between purging and admixture shapes genetic load in an invasive guppy population
Interplay between purging and admixture shapes genetic load in an invasive guppy population Open
Demographic history can shape the genetic load of populations by influencing the efficacy of selection, levels of heterozygosity, and by incorporation of new variants via gene flow. Understanding these dynamics is crucial for identifying t…
View article: Fighting to persist: Genetic rescue increases long-term fitness despite elevated genetic load
Fighting to persist: Genetic rescue increases long-term fitness despite elevated genetic load Open
Genetic rescue (GR) can restore fitness in small genetically depauperate populations, however, long-term effectiveness, impact of rescuer quality and introduced deleterious load on population persistence remains uncertain. Using a male-dim…
View article: Fighting Through the Heat: How Male Aggression Influences Demography Under Recurrent Heatwaves
Fighting Through the Heat: How Male Aggression Influences Demography Under Recurrent Heatwaves Open
Sexual selection is a potent evolutionary force that can enhance adaptation and reduce mutational load, while simultaneously reducing survival, or causing sexual conflict that reduces fitness of one or both sexes. Many populations face ext…
View article: Strong sexual selection reduces population size and hinders population recovery after heat stress
Strong sexual selection reduces population size and hinders population recovery after heat stress Open
View article: Sex-specific recombination landscape in a species with holocentric chromosomes
Sex-specific recombination landscape in a species with holocentric chromosomes Open
The rate and chromosomal positioning of meiotic recombination significantly affects the distribution of the genetic diversity in eukaryotic genomes. Many studies have revealed sex-specific recombination patterns, with male recombination ty…
View article: Cytoplasmic incompatibility associated with Wolbachia strains differing in the presence of cif genes
Cytoplasmic incompatibility associated with Wolbachia strains differing in the presence of cif genes Open
Wolbachia is a widespread bacterial endosymbiont and its maternal transmission favours the selfish manipulation of host reproduction to increases in frequency. One such manipulation is cytoplasmic incompatibility (CI), where uninfected fem…
View article: Small-scale genetic structure of the bulb mite Rhizoglyphus robini populations
Small-scale genetic structure of the bulb mite Rhizoglyphus robini populations Open
Bulb mites are an economically significant pest of subterranean parts of plants and a versatile laboratory animal. However, genetic structure of their populations remains unknown. To fill this gap in our knowledge of their biology, we set-…
View article: Genomic evidence that a sexually selected trait captures genome-wide variation and facilitates the purging of genetic load
Genomic evidence that a sexually selected trait captures genome-wide variation and facilitates the purging of genetic load Open
View article: Long term patterns of association between MHC and helminth burdens in the bank vole support Red Queen dynamics
Long term patterns of association between MHC and helminth burdens in the bank vole support Red Queen dynamics Open
Major histocompatibility complex (MHC) genes encode proteins crucial for adaptive immunity of vertebrates. Negative frequency‐dependent selection (NFDS), resulting from adaptation of parasites to common MHC types, has been hypothesized to …
View article: Adaptive immune response selects for increased body size - dataset
Adaptive immune response selects for increased body size - dataset Open
The dataset for the manuscript " Adaptive immune response selects for increased body size ". The dataset is packed in ZIP archive 'Dataset_Ejsmond_etal_2022.zip' with variables and description of variables saved in Matlab workspaces.
View article: Adaptive immune response selects for increased body size - dataset
Adaptive immune response selects for increased body size - dataset Open
The dataset for the manuscript " Adaptive immune response selects for increased body size ". The dataset is packed in ZIP archive 'Dataset_Ejsmond_etal_2022.zip' with variables and description of variables saved in Matlab workspaces.
View article: Review for "Contemporary selection on MHC genes in a free‐living ruminant population"
Review for "Contemporary selection on MHC genes in a free‐living ruminant population" Open
View article: Functional immunogenetic variation, rather than local adaptation, predicts ectoparasite infection intensity in a model fish species
Functional immunogenetic variation, rather than local adaptation, predicts ectoparasite infection intensity in a model fish species Open
Natural host populations differ in their susceptibility to infection by parasites, and these intra-population differences are still an incompletely understood component of host-parasite dynamics. In this study, we used controlled infection…
View article: Correction to: Balancing selection versus allele and supertype turnover in MHC class II genes in guppies
Correction to: Balancing selection versus allele and supertype turnover in MHC class II genes in guppies Open
View article: Sexual and ecological selection on a sexual conflict gene
Sexual and ecological selection on a sexual conflict gene Open
Sexual selection and conflict can act on genes with important metabolic functions, potentially shaping standing genetic variance in such genes and thus evolutionary potential of populations. Here, using experimental evolution, we show how …
View article: Author response for "RNA‐Seq analysis of the guppy immune response against <i>Gyrodactylus bullatarudis</i> infection"
Author response for "RNA‐Seq analysis of the guppy immune response against <i>Gyrodactylus bullatarudis</i> infection" Open
View article: Expansion of frozen hybrids in the guppy ectoparasite,<i>Gyrodactylus turnbulli</i>
Expansion of frozen hybrids in the guppy ectoparasite,<i>Gyrodactylus turnbulli</i> Open
Hybridization is one of the major factors contributing to the emergence of highly successful parasites. Hybrid vigor can play an important role in this process, but subsequent rounds of recombination in the hybrid population may dilute its…
View article: Electronic Supplementary Materials from Mating preferences can drive expansion or contraction of major histocompatibility complex gene family
Electronic Supplementary Materials from Mating preferences can drive expansion or contraction of major histocompatibility complex gene family Open
Contents: Supplementary Material 1: Detailed description of the agent-based model Supplementary Tab. S1 : Mating preference rules tested in simulations Supplementary Table 2 : Parametrisation of the model Supplementary Table 3 : Results of…
View article: Evolution of major histocompatibility complex gene copy number
Evolution of major histocompatibility complex gene copy number Open
MHC genes, which code for proteins responsible for presenting pathogen-derived antigens to the host immune system, show remarkable copy-number variation both between and within species. However, the evolutionary forces driving this variati…
View article: hawkes_et_al_data from Sexual selection drives the evolution of male wing interference patterns
hawkes_et_al_data from Sexual selection drives the evolution of male wing interference patterns Open
This is all the raw data
View article: New supplemtary tables from Sexual selection drives the evolution of male wing interference patterns
New supplemtary tables from Sexual selection drives the evolution of male wing interference patterns Open
A list of full statistical models for wing data
View article: Sexual selection drives the evolution of wing interference patterns
Sexual selection drives the evolution of wing interference patterns Open
The seemingly transparent wings of many insects have recently been found to display dramatic structural coloration. These structural colours (wing interference patterns: WIPs) may be involved in species recognition and mate choice, yet lit…
View article: The role of MHC supertypes in promoting trans-species polymorphism remains an open question
The role of MHC supertypes in promoting trans-species polymorphism remains an open question Open
View article: Immunogenetic novelty confers a selective advantage in host–pathogen coevolution
Immunogenetic novelty confers a selective advantage in host–pathogen coevolution Open
The major histocompatibility complex (MHC) is crucial to the adaptive immune response of vertebrates and is among the most polymorphic gene families known. Its high diversity is usually attributed to selection imposed by fast-evolving path…
View article: Raw data from Fitness consequences of threshold trait expression subject to environmental cues
Raw data from Fitness consequences of threshold trait expression subject to environmental cues Open
Excel spreadsheet.
View article: Comprehensive profiling of TCRβ repertoire in a non-model species (the bank vole) using high-throughput sequencing
Comprehensive profiling of TCRβ repertoire in a non-model species (the bank vole) using high-throughput sequencing Open
In recent years, immune repertoire profiling with high-throughput sequencing (HTS) has advanced our understanding of adaptive immunity. However, fast progress in the field applied mostly to human and mouse research, with only few studies d…
View article: De novo transcriptome assembly facilitates characterisation of fast-evolving gene families, MHC class I in the bank vole (Myodes glareolus)
De novo transcriptome assembly facilitates characterisation of fast-evolving gene families, MHC class I in the bank vole (Myodes glareolus) Open
View article: Transcriptomics of Intralocus Sexual Conflict: Gene Expression Patterns in Females Change in Response to Selection on a Male Secondary Sexual Trait in the Bulb Mite
Transcriptomics of Intralocus Sexual Conflict: Gene Expression Patterns in Females Change in Response to Selection on a Male Secondary Sexual Trait in the Bulb Mite Open
Intralocus sexual conflict (IASC) prevents males and females from reaching their disparate phenotypic optima and is widespread, but little is known about its genetic underpinnings. In Rhizoglyphus robini, a mite species with alternative ma…