Jack E. MacArthur
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View article: Deciphering the mechanism of protein aggregation and effects of inhibitors using single-molecule mass photometry
Deciphering the mechanism of protein aggregation and effects of inhibitors using single-molecule mass photometry Open
Aggregation of misfolded proteins is a prominent feature of many diseases and hence an attractive drug target. However, the small oligomers that are critical early species in the aggregation cascade are difficult to monitor directly owing …