Jack Samways
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View article: Ventricular repolarization is improved by His resynchronization therapy but not biventricular pacing
Ventricular repolarization is improved by His resynchronization therapy but not biventricular pacing Open
HBP-CRT improves LBBB-induced repolarization abnormalities through improved activation synchrony and ARI modulation. BVP-CRT does not improve, and appears to worsen, LV repolarization parameters.
View article: High‐Precision Hemodynamic and Echocardiographic Assessment of Pacing in Obstructive Hypertrophic Cardiomyopathy
High‐Precision Hemodynamic and Echocardiographic Assessment of Pacing in Obstructive Hypertrophic Cardiomyopathy Open
Background Left ventricular outflow obstruction drives symptoms and outcomes in obstructive hypertrophic cardiomyopathy (oHCM). Right ventricular pacing (RVP) can desynchronize the left ventricle to relieve this and allows control of atrio…
View article: An <i>in silico</i> guide for ventriculo-ventricular delay programming for left bundle branch-optimized cardiac resynchronization therapy
An <i>in silico</i> guide for ventriculo-ventricular delay programming for left bundle branch-optimized cardiac resynchronization therapy Open
Aims Left bundle branch pacing (LBBP)–optimized cardiac resynchronization therapy (LOT-CRT) can improve left ventricular (LV) activation when LBBP alone or conventional biventricular pacing are ineffective. However, the optimal programming…
View article: Comparison of non-invasive mapping with 12-lead ECG for the identification of left ventricular lateral wall activation
Comparison of non-invasive mapping with 12-lead ECG for the identification of left ventricular lateral wall activation Open
Background R-wave peak time (RWPT) is a measurement from the onset of the QRS complex to the apex of the R-wave. It reflects the time taken for excitation to spread from the endocardial to epicardial surface. RWPT in the unipolar chest lea…
View article: Design and implementation of Electronic Health Record Computerised Decision Support System (CDSS) trials: A Systematic Review
Design and implementation of Electronic Health Record Computerised Decision Support System (CDSS) trials: A Systematic Review Open
Objectives Conduct a systematic review of the existing evidence base pertaining to the conduct of randomised controlled trials of clinical decision support systems embedded within electronic health record systems. Further, to describe whet…
View article: Electrocardiographic predictors of haemodynamic benefit from biventricular pacing: the role of atrioventricular timing measures
Electrocardiographic predictors of haemodynamic benefit from biventricular pacing: the role of atrioventricular timing measures Open
Background Patients with heart failure (HF) and left bundle branch block (LBBB) are selected for biventricular pacing (BVP) cardiac resynchronisation therapy (CRT) based on their 12-lead ECG QRS complex duration (QRSd). This is due to the …
View article: Catheter Ablation for Ventricular Tachycardia After MI: A Reconstructed Individual Patient Data Meta-analysis of Randomised Controlled Trials
Catheter Ablation for Ventricular Tachycardia After MI: A Reconstructed Individual Patient Data Meta-analysis of Randomised Controlled Trials Open
Background: The prognostic impact of ventricular tachycardia (VT) catheter ablation is an important outstanding research question. We undertook a reconstructed individual patient data meta-analysis of randomised controlled trials comparing…
View article: Catheter ablation for ventricular tachycardia after myocardial infarction: meta-analysis of randomised controlled trials
Catheter ablation for ventricular tachycardia after myocardial infarction: meta-analysis of randomised controlled trials Open
Background The prognostic impact of ventricular tachycardia (VT) catheter ablation is an important outstanding research question. Purpose We undertook a reconstructed individual patient data meta-analysis of randomised controlled trials co…
View article: The prognostic impact of specialist cardiology input in patients admitted for heart failure and normal ejection fraction
The prognostic impact of specialist cardiology input in patients admitted for heart failure and normal ejection fraction Open
Aims Specialist cardiology care is associated with a prognostic benefit in patients with heart failure (HF) with reduced ejection fraction (HFrEF) admitted with decompensated HF. However, up to one third of patients admitted with HF and no…
View article: Smartphone-Based Remote Monitoring in Heart Failure With Reduced Ejection Fraction: Retrospective Cohort Study of Secondary Care Use and Costs
Smartphone-Based Remote Monitoring in Heart Failure With Reduced Ejection Fraction: Retrospective Cohort Study of Secondary Care Use and Costs Open
Background Despite effective therapies, the economic burden of heart failure with reduced ejection fraction (HFrEF) is driven by frequent hospitalizations. Treatment optimization and admission avoidance rely on frequent symptom reviews and…
View article: Smartphone-Based Remote Monitoring for Chronic Heart Failure: Mixed Methods Analysis of User Experience From Patient and Nurse Perspectives
Smartphone-Based Remote Monitoring for Chronic Heart Failure: Mixed Methods Analysis of User Experience From Patient and Nurse Perspectives Open
Background Community-based management by heart failure specialist nurses (HFSNs) is key to improving self-care in heart failure with reduced ejection fraction. Remote monitoring (RM) can aid nurse-led management, but in the literature, use…
View article: Smartphone-Based Remote Monitoring in Heart Failure With Reduced Ejection Fraction: Retrospective Cohort Study of Secondary Care Use and Costs (Preprint)
Smartphone-Based Remote Monitoring in Heart Failure With Reduced Ejection Fraction: Retrospective Cohort Study of Secondary Care Use and Costs (Preprint) Open
BACKGROUND Despite effective therapies, the economic burden of heart failure with reduced ejection fraction (HFrEF) is driven by frequent hospitalizations. Treatment optimization and admission avoidance rely on frequent symptom reviews an…
View article: Smartphone-based remote monitoring (RM) in chronic heart failure reduces emergency hospital attendances, unplanned admissions and secondary care costs: a retrospective cohort study
Smartphone-based remote monitoring (RM) in chronic heart failure reduces emergency hospital attendances, unplanned admissions and secondary care costs: a retrospective cohort study Open
Background Despite effective therapies, the economic burden of heart failure with reduced ejection fraction (HFrEF) is driven by frequent hospital attendances [1]. Treatment optimisation and admission avoidance relies on frequent symptom r…
View article: Smartphone-based remote monitoring in chronic heart failure: patient & clinician user experience, impact on patient engagement and quality of life
Smartphone-based remote monitoring in chronic heart failure: patient & clinician user experience, impact on patient engagement and quality of life Open
Background Heart failure with reduced ejection fraction (HFrEF) lowers patients' quality of life (QoL) [1]. Digital interventions such as ESC's “Heart Failure Matters” website aim to encourage patient-engagement & self-management [2], whic…
View article: 522 THE IMPACT OF SPECIALIST CARDIOLOGY INPUT ON OUTCOMES IN PATIENTS ADMITTED FOR HEART FAILURE WITH NORMAL EJECTION FRACTION. A MULTICENTRE STUDY
522 THE IMPACT OF SPECIALIST CARDIOLOGY INPUT ON OUTCOMES IN PATIENTS ADMITTED FOR HEART FAILURE WITH NORMAL EJECTION FRACTION. A MULTICENTRE STUDY Open
Aims Specialist cardiology care is associated with a prognostic benefit in patients with HF with reduced ejection fraction (HFrEF) admitted with decompensated heart failure (HF). However, up to one third of patients admitted with HF and no…
View article: Smartphone-Based Remote Monitoring for Chronic Heart Failure: Mixed Methods Analysis of User Experience From Patient and Nurse Perspectives (Preprint)
Smartphone-Based Remote Monitoring for Chronic Heart Failure: Mixed Methods Analysis of User Experience From Patient and Nurse Perspectives (Preprint) Open
BACKGROUND Community-based management by heart failure specialist nurses (HFSNs) is key to improving self-care in heart failure with reduced ejection fraction. Remote monitoring (RM) can aid nurse-led management, but in the literature, us…
View article: Catheter ablation improves cardiovascular outcomes in patients with atrial fibrillation and heart failure: a meta-analysis of randomized controlled trials
Catheter ablation improves cardiovascular outcomes in patients with atrial fibrillation and heart failure: a meta-analysis of randomized controlled trials Open
Aims The effect of atrial fibrillation catheter ablation on cardiovascular outcomes in heart failure is an important outstanding research question. We undertook a meta-analysis of randomized controlled trials comparing ablation to medical …
View article: Smartphone-based remote monitoring (RM) in chronic heart failure reduces emergency hospital attendances, unplanned admissions and secondary care costs: a retrospective cohort study
Smartphone-based remote monitoring (RM) in chronic heart failure reduces emergency hospital attendances, unplanned admissions and secondary care costs: a retrospective cohort study Open
Background Despite effective therapies, the economic burden of heart failure with reduced ejection fraction (HFrEF) is driven by frequent hospital attendances [1]. Treatment optimisation and admission avoidance relies on frequent symptom r…
View article: Smartphone-based remote monitoring in chronic heart failure: patient & clinician user experience, impact on patient engagement and quality of life
Smartphone-based remote monitoring in chronic heart failure: patient & clinician user experience, impact on patient engagement and quality of life Open
Background Heart failure with reduced ejection fraction (HFrEF) lowers patients' quality of life (QoL) [1]. Digital interventions such as ESC's “Heart Failure Matters” website aim to encourage patient-engagement & self-management [2], whic…
View article: The reporting standards of randomised controlled trials in leading medical journals between 2019 and 2020: a systematic review
The reporting standards of randomised controlled trials in leading medical journals between 2019 and 2020: a systematic review Open
Randomised controlled trials (RCTs) are the gold standard study design used to evaluate the safety and effectiveness of healthcare interventions. The reporting quality of RCTs is of fundamental importance for readers to appropriately analy…
View article: SYSTEMATIC REVIEW PROTOCOL: The reporting standards of Randomised Clinical Trials in leading medical journals between 2019-2020
SYSTEMATIC REVIEW PROTOCOL: The reporting standards of Randomised Clinical Trials in leading medical journals between 2019-2020 Open
This is a systematic review protocol which outlines the basis and methodology for our intended review which at the time of writing is in the study screening phase. Our aim is to answer the fundamental questions: To systematically identify …
View article: P1665Outcomes and risk factors for recurrent restenosis in patients treated for coronary in-stent restenosis
P1665Outcomes and risk factors for recurrent restenosis in patients treated for coronary in-stent restenosis Open
332 Coronary interventions: stents 27.4% (n=983) on ticagrelor and 3.7% (n=131) on prasugrel.Patients receiving clopidogrel were older than other groups (64.3±11.2 vs. 62.1±10.9 vs. 58.8 vs. ±11.1yrs),with higher prevalence of diabetes (33…