Jack T. Sumner
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View article: Maternal Colonization, Perinatal Exposure, and Neonatal Acquisition of Resistant Enterobacterales
Maternal Colonization, Perinatal Exposure, and Neonatal Acquisition of Resistant Enterobacterales Open
Background Enterobacterales with ampicillin (AmpR-E) and ceftriaxone resistance (CefR-E) are globally prevalent. Perinatal transmission and infections with CefR-E strains are associated with higher mortality, morbidity, and healthcare cost…
View article: Large language models accurately identify immunosuppression in intensive care unit patients
Large language models accurately identify immunosuppression in intensive care unit patients Open
Objective Rule-based structured data algorithms and natural language processing (NLP) approaches applied to unstructured clinical notes have limited accuracy and poor generalizability for identifying immunosuppression. Large language model…
View article: Metagenomic Profiling of Airborne Microbial Communities from Aircraft Filters and Face Masks
Metagenomic Profiling of Airborne Microbial Communities from Aircraft Filters and Face Masks Open
Airborne microbial communities, although often challenging to study due to low biomass, play crucial roles in public health and pathogen transmission. Through shotgun metagenomics, this study utilizes non-invasive air sampling of face mask…
View article: Phage communities in household-related biofilms correlate with bacterial hosts
Phage communities in household-related biofilms correlate with bacterial hosts Open
The average American spends 93% of their time in built environments, almost 70% of that is in their place of residence. Human health and well-being are intrinsically tied to the quality of our personal environments and the microbiomes that…
View article: Transitions in lung microbiota landscape associate with distinct patterns of pneumonia progression
Transitions in lung microbiota landscape associate with distinct patterns of pneumonia progression Open
SUMMARY The precise microbial determinants driving clinical outcomes in severe pneumonia are unknown. Competing ecological forces produce dynamic microbiota states in health; infection and treatment effects on microbiota state must be defi…
View article: Maternal Colonization, Perinatal Exposure, and Neonatal Acquisition of Resistant Enterobacterales
Maternal Colonization, Perinatal Exposure, and Neonatal Acquisition of Resistant Enterobacterales Open
Background Multi-drug resistant Enterobacterales, in particular with ceftriaxone resistance (CefR-E), are globally prevalent. Pregnant people colonized with resistant Enterobacterales are at risk of perinatally transmitting to neonates; in…
View article: 96. Maternal Colonization, Perinatal Exposure, and Neonatal Acquisition of Resistant Enterobacterales
96. Maternal Colonization, Perinatal Exposure, and Neonatal Acquisition of Resistant Enterobacterales Open
Background Extended Spectrum Beta-Lactamase producing Enterobacterales (ESBL-E) are globally prevalent. Pregnant people colonized with ESBL-E are at risk of perinatally transmitting to neonates, in whom infections with these strains are as…
View article: De novo genome assembly and comparative genomics for the colonial ascidian <i>Botrylloides violaceus</i>
De novo genome assembly and comparative genomics for the colonial ascidian <i>Botrylloides violaceus</i> Open
Ascidians have the potential to reveal fundamental biological insights related to coloniality, regeneration, immune function, and the evolution of these traits. This study implements a hybrid assembly technique to produce a genome assembly…
View article: <i>De novo</i>genome assembly and comparative genomics for the colonial ascidian<i>Botrylloides violaceus</i>
<i>De novo</i>genome assembly and comparative genomics for the colonial ascidian<i>Botrylloides violaceus</i> Open
Ascidians have the potential to reveal fundamental biological insights related to coloniality, regeneration, immune function, and the evolution of these traits. This study implements a hybrid assembly technique to produce a genome assembly…
View article: Clinically Relevant Pathogens on Surfaces Display Differences in Survival and Transcriptomic Response in Relation to Probiotic and Traditional Cleaning Strategies
Clinically Relevant Pathogens on Surfaces Display Differences in Survival and Transcriptomic Response in Relation to Probiotic and Traditional Cleaning Strategies Open
Indoor surfaces are paradoxically presumed to be both colonized by pathogens, necessitating disinfection, and “microbial wastelands.” In these resource-poor, dry environments, competition and decay are thought to be important drivers of mi…