Jack W. Rutter
YOU?
Author Swipe
View article: How can we Engineer Bacteria to Treat Human Diseases?
How can we Engineer Bacteria to Treat Human Diseases? Open
Bacteria are microscopic single-celled organisms that are invisible to the naked eye. They live all over the human body, and they can help keep people healthy by producing vitamins and breaking down food. Scientists can even use bacteria t…
View article: Bacterial microcompartment utilization in the human commensal <i>Escherichia coli</i> Nissle 1917
Bacterial microcompartment utilization in the human commensal <i>Escherichia coli</i> Nissle 1917 Open
Bacterial microcompartments (BMCs) are self-assembled protein structures often utilized by bacteria as a modular metabolic unit, enabling the catalysis and utilization of less common carbon and nitrogen sources within a self-contained comp…
View article: Engaging cancer patients on their attitudes towards microbiome engineering technologies
Engaging cancer patients on their attitudes towards microbiome engineering technologies Open
Microbiome engineering aims to develop engineered live biotherapeutic products to diagnose and treat human disease. One of the most active areas is in the engineering of modified bacteria that act as cancer therapeutics, with many products…
View article: A bacteriocin expression platform for targeting pathogenic bacterial species
A bacteriocin expression platform for targeting pathogenic bacterial species Open
Bacteriocins are antimicrobial peptides that are naturally produced by many bacteria. They hold great potential in the fight against antibiotic resistant bacteria, including ESKAPE pathogens. Engineered live biotherapeutic products (eLBPs)…
View article: Emergent digital bio-computation through spatial diffusion and engineered bacteria
Emergent digital bio-computation through spatial diffusion and engineered bacteria Open
View article: Bacterial microcompartment utilisation in the human commensal<i>Escherichia coli</i>Nissle 1917
Bacterial microcompartment utilisation in the human commensal<i>Escherichia coli</i>Nissle 1917 Open
Bacterial microcompartments (BMCs) are self-assembled protein structures often utilised by bacteria as a modular metabolic unit, enabling the catalysis and utilisation of less common carbon and nitrogen sources within a self-contained comp…
View article: Dataset for publication ("A bacteriocin expression platform for targeting pathogenic bacterial species")
Dataset for publication ("A bacteriocin expression platform for targeting pathogenic bacterial species") Open
Experimental dataset used to create Figures 2-7 of manuscript: "A bacteriocin expression platform for targeting pathogenic bacterial species".
View article: An antimicrobial peptide expression platform for targeting pathogenic bacterial species
An antimicrobial peptide expression platform for targeting pathogenic bacterial species Open
Bacteriocins are antimicrobial peptides that are naturally produced by many bacteria. They hold great potential in the fight against antibiotic resistant bacteria, including ESKAPE pathogens. However, they often have low stability in vivo a…
View article: Dataset for publication ("An antimicrobial peptide expression platform for targeting pathogenic bacterial species")
Dataset for publication ("An antimicrobial peptide expression platform for targeting pathogenic bacterial species") Open
Experimental dataset used to create Figures 2-4 of manuscript: "An antimicrobial peptide expression platform for targeting pathogenic bacterial species" (preprint doi: https://doi.org/10.1101/2023.10.09.561505).
View article: An antimicrobial peptide expression platform for targeting pathogenic bacterial species
An antimicrobial peptide expression platform for targeting pathogenic bacterial species Open
Bacteriocins are antimicrobial peptides that are naturally produced by many bacteria. They hold great potential in the fight against antibiotic resistant bacteria, including ESKAPE pathogens. However, they often have low stability in vivo …
View article: Emergent digital bio-computation through spatial diffusion and engineered bacteria
Emergent digital bio-computation through spatial diffusion and engineered bacteria Open
Data and code to reproduce figures
View article: Emergent digital bio-computation through spatial diffusion and engineered bacteria
Emergent digital bio-computation through spatial diffusion and engineered bacteria Open
Building computationally capable biological systems has long been an aim of synthetic biology. The potential utility of biocomputing devices ranges from biosafety and environmental applications to diagnosis and personalised medicine. Here …
View article: Microbiome engineering: engineered live biotherapeutic products for treating human disease
Microbiome engineering: engineered live biotherapeutic products for treating human disease Open
The human microbiota is implicated in many disease states, including neurological disorders, cancer, and inflammatory diseases. This potentially huge impact on human health has prompted the development of microbiome engineering methods, wh…
View article: Engineered acetoacetate‐inducible whole‐cell biosensors based on the AtoSC two‐component system
Engineered acetoacetate‐inducible whole‐cell biosensors based on the AtoSC two‐component system Open
Whole‐cell biosensors hold potential in a variety of industrial, medical, and environmental applications. These biosensors can be constructed through the repurposing of bacterial sensing mechanisms, including the common two‐component syste…
View article: Engineered acetoacetate-inducible whole-cell biosensors based on the AtoSC two-component system
Engineered acetoacetate-inducible whole-cell biosensors based on the AtoSC two-component system Open
Data and code for manuscript.
View article: Engineered acetoacetate-inducible whole-cell biosensors based on the AtoSC two-component system
Engineered acetoacetate-inducible whole-cell biosensors based on the AtoSC two-component system Open
Data and code for manuscript.
View article: Detecting Changes in the Caenorhabditis elegans Intestinal Environment Using an Engineered Bacterial Biosensor
Detecting Changes in the Caenorhabditis elegans Intestinal Environment Using an Engineered Bacterial Biosensor Open
Data for the figures in the manuscript https://pubs.acs.org/doi/10.1021/acssynbio.9b00166 Abstract: Caenorhabditis elegans has become a key model organism within biology. In particular, the transparent gut, rapid growing time, an…
View article: Detecting Changes in the Caenorhabditis elegans Intestinal Environment Using an Engineered Bacterial Biosensor
Detecting Changes in the Caenorhabditis elegans Intestinal Environment Using an Engineered Bacterial Biosensor Open
Data for the figures in the manuscript https://pubs.acs.org/doi/10.1021/acssynbio.9b00166 Abstract: Caenorhabditis elegans has become a key model organism within biology. In particular, the transparent gut, rapid growing time, an…
View article: Detecting Changes in the Caenorhabditis elegans Intestinal Environment Using an Engineered Bacterial Biosensor
Detecting Changes in the Caenorhabditis elegans Intestinal Environment Using an Engineered Bacterial Biosensor Open
Data for the figures in the manuscript https://pubs.acs.org/doi/10.1021/acssynbio.9b00166 Abstract: Caenorhabditis elegans has become a key model organism within biology. In particular, the transparent gut, rapid growing time, an…
View article: Detecting Changes in the <i>Caenorhabditis elegans</i> Intestinal Environment Using an Engineered Bacterial Biosensor
Detecting Changes in the <i>Caenorhabditis elegans</i> Intestinal Environment Using an Engineered Bacterial Biosensor Open
Caenorhabditis elegans has become a key model organism within biology. In particular, the transparent gut, rapid growing time, and ability to create a defined gut microbiota make it an ideal candidate organism for understanding and …
View article: Detecting changes in the <i>Caenorhabditis elegans</i> intestinal environment using an engineered bacterial biosensor
Detecting changes in the <i>Caenorhabditis elegans</i> intestinal environment using an engineered bacterial biosensor Open
Caenorhabditis elegans has become a key model organism within biology. In particular, the transparent gut, rapid growing time and ability to create a defined gut microbiota make it an ideal candidate organism for understanding and engineer…
View article: Two New Plasmid Post-segregational Killing Mechanisms for the Implementation of Synthetic Gene Networks in Escherichia coli
Two New Plasmid Post-segregational Killing Mechanisms for the Implementation of Synthetic Gene Networks in Escherichia coli Open
View article: Engineered acetoacetate-inducible whole-cell biosensors based on the AtoSC two-component system
Engineered acetoacetate-inducible whole-cell biosensors based on the AtoSC two-component system Open
Whole-cell biosensors hold potential in a variety of industrial, medical and environmental applications. These biosensors can be constructed through the repurposing of bacterial sensing mechanisms, including the common two-component system…