Jaclyn Swan
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View article: Deciphering the Fasciola hepatica Glycocode and Its Involvement in Host–Parasite Interactions
Deciphering the Fasciola hepatica Glycocode and Its Involvement in Host–Parasite Interactions Open
The zoonotic disease fasciolosis poses a significant global threat to both humans and livestock. The causative agent of fasciolosis is Fasciola hepatica, which is commonly referred to as liver fluke. The emergence of drug resistance has un…
View article: Reduced efficacy of an anti-toxin vaccine from senescence-driven attenuation of toxin virulence
Reduced efficacy of an anti-toxin vaccine from senescence-driven attenuation of toxin virulence Open
It remains unclear why vaccines targeting prominent microbial virulence factors often fail in clinical trials. Because microbial virulence depends on interaction with the host immune system, we investigated how changes in host immune funct…
View article: Deciphering the <em>Fasciola hepatica</em> Glycocode and Its Involvement in Host-Parasite Interactions
Deciphering the <em>Fasciola hepatica</em> Glycocode and Its Involvement in Host-Parasite Interactions Open
The zoonotic disease fasciolosis poses a significant global threat to both humans and livestock. The causative agent of fasciolosis is Fasciola hepatica which is commonly referred to as liver fluke. The emergence of drug resistance has und…
View article: The Sialome of the Retina, Alteration in Age-Related Macular Degeneration Pathology, and Potential Impacts on Complement Factor H
The Sialome of the Retina, Alteration in Age-Related Macular Degeneration Pathology, and Potential Impacts on Complement Factor H Open
The sialome of the human retina is altered in AMD. This may affect FH binding and, consequently, alternative complement pathway regulation.
View article: The sialome of the retina, alteration in age-related macular degeneration (AMD) pathology and potential impacts on Complement Factor H
The sialome of the retina, alteration in age-related macular degeneration (AMD) pathology and potential impacts on Complement Factor H Open
Purpose Little is known about sialic acids of the human retina, despite their integral role in self/non-self-discrimination by complement factor H (CFH), the alternative complement pathway inhibitor. Methods A custom sialoglycan microarray…
View article: Teladorsagia Circumcincta Galectin-Mucosal Interactome in Sheep
Teladorsagia Circumcincta Galectin-Mucosal Interactome in Sheep Open
Teladorsagia circumcincta is the most important gastrointestinal parasite in the livestock industry in temperate regions around the world, causing great economic losses. The infective third-stage larvae (L3) of Teladorsagia circumcincta se…
View article: Towards Understanding the Liver Fluke Transmission Dynamics on Farms: Detection of Liver Fluke Transmitting Snail and Liver Fluke-Specific Environmental DNA in Water Samples from an Irrigated Dairy Farm in Southeast Australia
Towards Understanding the Liver Fluke Transmission Dynamics on Farms: Detection of Liver Fluke Transmitting Snail and Liver Fluke-Specific Environmental DNA in Water Samples from an Irrigated Dairy Farm in Southeast Australia Open
Background Livestock production around the world is impacted by liver fluke ( Fasciola spp.) infection resulting in serious economic losses to the beef, dairy and sheep industries with significant losses of about $90 million per annum in A…
View article: Proteomic identification of galectin-11 and 14 ligands from <i>Haemonchus contortus</i>
Proteomic identification of galectin-11 and 14 ligands from <i>Haemonchus contortus</i> Open
Haemonchus contortus is the most pathogenic nematode of small ruminants. Infection in sheep and goats results in anaemia that decreases animal productivity and can ultimately cause death. The involvement of ruminant-specific galectin-11 (L…
View article: Proteomic identification of Galectin-11 and 14 ligands from <i> </i> <i>Haemonchus contortus</i>
Proteomic identification of Galectin-11 and 14 ligands from <i> </i> <i>Haemonchus contortus</i> Open
Haemonchus contortus is the most pathogenic nematode of small ruminants. Infection in sheep and goats results in anaemia that decreases animal productivity and can ultimately cause death. The involvement of ruminant-specific galectin-11 (L…
View article: Proteomic identification of Galectin-11 and 14 ligands from <i> </i> <i>Haemonchus contortus</i>
Proteomic identification of Galectin-11 and 14 ligands from <i> </i> <i>Haemonchus contortus</i> Open
Haemonchus contortus is the most pathogenic nematode of small ruminants. Infection in sheep and goats results in anaemia that decreases animal productivity and can ultimately cause death. The involvement of ruminant-specific galectin-11 (L…