Jacob E. Dander
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View article: Activation of C–O and C–N Bonds Using Non-Precious-Metal Catalysis
Activation of C–O and C–N Bonds Using Non-Precious-Metal Catalysis Open
ADVERTISEMENT RETURN TO ISSUEPREVViewpointNEXTActivation of C–O and C–N Bonds Using Non-Precious-Metal CatalysisTimothy B. BoitTimothy B. BoitDepartment of Chemistry and Biochemistry, University of California, Los Angeles, California 90095…
View article: Ni-Catalyzed Suzuki–Miyaura Cross-Coupling of Aliphatic Amides on the Benchtop
Ni-Catalyzed Suzuki–Miyaura Cross-Coupling of Aliphatic Amides on the Benchtop Open
Suzuki-Miyaura cross-couplings of amides offer an approach to the synthesis of ketones that avoids the use of basic or pyrophoric nucleophiles. However, these reactions require glovebox manipulations, thus limiting their practicality. We r…
View article: Chemoenzymatic conversion of amides to enantioenriched alcohols in aqueous medium
Chemoenzymatic conversion of amides to enantioenriched alcohols in aqueous medium Open
One-pot reactions that combine non-enzymatic and biocatalytic transformations represent an emerging strategy in chemical synthesis. Some of the most powerful chemoenzymatic methodologies, although uncommon, are those that form a carbon–car…
View article: Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases
Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases Open
Fungal polyketide synthases (PKSs) can function collaboratively to synthesize natural products of significant structural diversity. Here we present a new mode of collaboration between a highly reducing PKS (HRPKS) and a PKS-nonribosomal pe…
View article: Breaking Amides using Nickel Catalysis
Breaking Amides using Nickel Catalysis Open
Amides have been widely studied for decades, but their synthetic utility has remained limited in reactions that proceed with rupture of the amide C-N bond. Using Ni catalysis, we have found that amides can now be strategically employed in …
View article: Nickel-catalyzed transamidation of aliphatic amide derivatives
Nickel-catalyzed transamidation of aliphatic amide derivatives Open
We report a two-step approach to achieve the transamidation of secondary aliphatic amides using non-precious metal catalysis.
View article: CCDC 1566347: Experimental Crystal Structure Determination
CCDC 1566347: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Benchtop Delivery of Ni(cod)<sub>2</sub> using Paraffin Capsules
Benchtop Delivery of Ni(cod)<sub>2</sub> using Paraffin Capsules Open
A facile method that allows for Ni(cod)2 to be used on the benchtop is reported. The procedure involves the preparation of paraffin-Ni(cod)2 capsules, which are stable to air and moisture. It is demonstrated that these readily available ca…