Jacob Melgaard
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View article: Novel non-invasive ECG imaging method based on the 12-lead ECG for reconstruction of ventricular activation: A proof-of-concept study
Novel non-invasive ECG imaging method based on the 12-lead ECG for reconstruction of ventricular activation: A proof-of-concept study Open
Aim Current non-invasive electrocardiographic imaging (ECGi) methods are often based on complex body surface potential mapping, limiting the clinical applicability. The aim of this pilot study was to evaluate the ability of a novel non-inv…
View article: Prediction of postoperative atrial fibrillation with postoperative epicardial electrograms
Prediction of postoperative atrial fibrillation with postoperative epicardial electrograms Open
Objectives. New-onset postoperative atrial fibrillation (POAF) is a common complication after cardiac surgery. The arrhythmia often entails a longer hospital stay, greater risk of other complications, and higher mortality both short- and l…
View article: Non-invasive estimation of QLV from the standard 12-lead ECG in patients with left bundle branch block
Non-invasive estimation of QLV from the standard 12-lead ECG in patients with left bundle branch block Open
Background: Cardiac resynchronization therapy (CRT) is a treatment for patients with heart failure and electrical dyssynchrony, i.e., left bundle branch block (LBBB) ECG pattern. CRT resynchronizes ventricular contraction with a right vent…
View article: Novel non-invasive 12-lead ECG-based imaging method with potential to guide and optimise right ventricular lead implantation
Novel non-invasive 12-lead ECG-based imaging method with potential to guide and optimise right ventricular lead implantation Open
Funding Acknowledgements Type of funding sources: Private grant(s) and/or Sponsorship. Main funding source(s): Svend Andersens Foundation Karl G Andersens Foundation Helsefonden Background Right ventricular (RV) pacing may induce electrica…
View article: Clinical implications of electrocardiographic bundle branch block in primary care
Clinical implications of electrocardiographic bundle branch block in primary care Open
Objectives Electrocardiographic bundle branch block (BBB) is common but the prognostic implications in primary care are unclear. We sought to investigate the relationship between electrocardiographic BBB subtypes and the risk of cardiovasc…
View article: Protection against severe hypokalemia but impaired cardiac repolarization after intense rowing exercise in healthy humans receiving salbutamol
Protection against severe hypokalemia but impaired cardiac repolarization after intense rowing exercise in healthy humans receiving salbutamol Open
Intense exercise induces pronounced hyperkalemia, followed by transient hypokalemia in recovery. We investigated whether the β 2 agonist salbutamol attenuated the exercise hyperkalemia and exacerbated the postexercise hypokalemia, and whet…
View article: A novel automatic electrocardiographic algorithm for assessing Sclarovsky-Birnbaum Severity of Ischemia from pre-hospital ECG in ST-Segment Elevation Myocardial Infarction
A novel automatic electrocardiographic algorithm for assessing Sclarovsky-Birnbaum Severity of Ischemia from pre-hospital ECG in ST-Segment Elevation Myocardial Infarction Open
Background: Terminal “QRS distortion” on the electrocardiogram (ECG) (based on Sclarovsky-Birnbaum Severity Grades of Ischemia) is a sign of severe ischemia and is associated with adverse cardiovas...
View article: A History of Drug‐Induced Torsades de Pointes Is Associated With T‐wave Morphological Abnormalities
A History of Drug‐Induced Torsades de Pointes Is Associated With T‐wave Morphological Abnormalities Open
The hypothesis of the study is that Torsades de pointes (TdP) history can be better identified using T‐wave morphology compared to Fridericia‐corrected QT interval (QTcF) at baseline. ECGs were recorded at baseline and during sotalol chall…
View article: Minimizing a Wireless Passive LC-Tank Sensor to Monitor Bladder Pressure: A Simulation Study
Minimizing a Wireless Passive LC-Tank Sensor to Monitor Bladder Pressure: A Simulation Study Open
In this simulation study, a wireless passive LC-tank sensor system was characterized. Given the application of continuous bladder monitoring, a specific system was proposed in terms of coil geometries and electronic circuitry. Coupling coe…
View article: A Vectorcardiographic Evaluation of the Consensus Criteria for Early Repolarization
A Vectorcardiographic Evaluation of the Consensus Criteria for Early Repolarization Open
A 2015 consensus paper proposed a unified definition of the early repolarization (ER) pattern based upon quantification of end-QRS notches and slurs in the ECG. In this study we investigated the relationship between end-QRS concave 'bite' …
View article: Temporal Alignment of Asynchronously Sampled Biomedical Signals
Temporal Alignment of Asynchronously Sampled Biomedical Signals Open
Temporal alignment of signals obtained using different acquisition systems is often complicated by asynchronous sampling.In the current study we aligned 3-lead ECGs recorded in a phonocardiogram setup with 12-lead Holter ECGs. Two signals …
View article: Effect of Sample Rate on saECG Spectrum
Effect of Sample Rate on saECG Spectrum Open
Signal-averaged ECG (saECG) has been used to show delayed ventricular activation and myocardial infarction, but alignment jitter acts as a low-pass filter.Jitter arises due to sampling of the signal, and due to imperfect alignment algorith…
View article: Automatic Segmentation of Mitral Leaflet Movement in Doppler Tissue M:Mode Ultrasound
Automatic Segmentation of Mitral Leaflet Movement in Doppler Tissue M:Mode Ultrasound Open
Introduction: Doppler Tissue M-Mode ultrasound facilitates a method for measuring both mitral and aortic valve opening and closing.These measures can be used when assessing global information about the cardiac cycle.The method depends on a…