Jacob Proaño
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View article: The polyether ionophore salinomycin targets multiple cellular pathways to block proliferative vitreoretinopathy pathology
The polyether ionophore salinomycin targets multiple cellular pathways to block proliferative vitreoretinopathy pathology Open
Proliferative vitreoretinopathy (PVR) is characterized by membranes that form in the vitreous cavity and on both surfaces of the retina, which results in the formation of tractional membranes that can cause retinal detachment and intrinsic…
View article: Antibody‐mediated inhibition of EGFR reduces phosphate excretion and induces hyperphosphatemia and mild hypomagnesemia in mice
Antibody‐mediated inhibition of EGFR reduces phosphate excretion and induces hyperphosphatemia and mild hypomagnesemia in mice Open
Monoclonal antibody therapies targeting the EGF receptor ( EGFR ) frequently result in hypomagnesemia in human patients. In contrast, EGFR tyrosine kinase inhibitors do not affect Mg 2+ balance in patients and only have a mild effect on Mg…