Jacob R. Thorstensen
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View article: Repetitive Transcranial Magnetic Stimulation in Adolescents With Persistent Postconcussion Symptoms After Mild Traumatic Brain Injury: An Open Label Safety and Feasibility Study
Repetitive Transcranial Magnetic Stimulation in Adolescents With Persistent Postconcussion Symptoms After Mild Traumatic Brain Injury: An Open Label Safety and Feasibility Study Open
View article: 5‐HT<sub>2</sub> antagonism indirectly increases motor unit discharge rate and cervicomedullary motor evoked potential amplitude during submaximal elbow flexions
5‐HT<sub>2</sub> antagonism indirectly increases motor unit discharge rate and cervicomedullary motor evoked potential amplitude during submaximal elbow flexions Open
Spinal motoneurone excitability is heavily regulated by serotonin via somatodendritic 5‐HT 2 receptors. However, the effects of these receptors on the excitability of motoneurones in the upper limb are not clearly understood. Therefore, th…
View article: Non‐homogeneous distribution of inhibitory inputs among motor units in response to nociceptive stimulation at moderate contraction intensity
Non‐homogeneous distribution of inhibitory inputs among motor units in response to nociceptive stimulation at moderate contraction intensity Open
Pain significantly influences movement, yet the neural mechanisms underlying the range of observed motor adaptations remain unclear. This study combined experimental data and in silico models to investigate the contribution of inhibitory a…
View article: Non-Homogeneous Distribution of Inhibitory Inputs Among Motor Units in Response to Nociceptive Stimulation
Non-Homogeneous Distribution of Inhibitory Inputs Among Motor Units in Response to Nociceptive Stimulation Open
Pain significantly influences movement, yet the neural mechanisms underlying the range of observed motor adaptations remain unclear. This study combined experimental data and in silico models to investigate the contribution of inhibitory a…
View article: Excitatory drive to spinal motoneurones is necessary for serotonin to modulate motoneurone excitability via 5‐HT <sub>2</sub> receptors in humans
Excitatory drive to spinal motoneurones is necessary for serotonin to modulate motoneurone excitability via 5‐HT <sub>2</sub> receptors in humans Open
Serotonin modulates corticospinal excitability, motoneurone firing rates and contractile strength via 5‐HT 2 receptors. However, the effects of these receptors on cortical and motoneurone excitability during voluntary contractions have not…
View article: Serotonergic and noradrenergic contributions to motor cortical and spinal motoneuronal excitability in humans
Serotonergic and noradrenergic contributions to motor cortical and spinal motoneuronal excitability in humans Open
View article: Excitatory drive to spinal motoneurones is necessary for serotonin to modulate motoneurone excitability via 5-HT<sub>2</sub>receptors in humans
Excitatory drive to spinal motoneurones is necessary for serotonin to modulate motoneurone excitability via 5-HT<sub>2</sub>receptors in humans Open
Serotonin modulates corticospinal excitability, motoneurone firing rates and contractile strength via 5-HT 2 receptors. However, the effects of these receptors on cortical and motoneurone excitability during voluntary contractions have not…
View article: 5‐HT <sub>2</sub> receptor antagonism reduces human motoneuron output to antidromic activation but not to stimulation of corticospinal axons
5‐HT <sub>2</sub> receptor antagonism reduces human motoneuron output to antidromic activation but not to stimulation of corticospinal axons Open
The intrinsic electrical properties of motoneurons strongly affect motoneuron excitability to fast‐acting excitatory ionotropic inputs. Serotonin (5‐HT) is a neurochemical that alters the intrinsic properties of motoneurons, whereby animal…
View article: Author response for "5‐HT <sub>2</sub> receptor antagonism reduces human motoneuron output to antidromic activation but not to stimulation of corticospinal axons"
Author response for "5‐HT <sub>2</sub> receptor antagonism reduces human motoneuron output to antidromic activation but not to stimulation of corticospinal axons" Open
View article: Enhanced serotonin availability amplifies fatigue perception and modulates the TMS‐induced silent period during sustained low‐intensity elbow flexions
Enhanced serotonin availability amplifies fatigue perception and modulates the TMS‐induced silent period during sustained low‐intensity elbow flexions Open
Key points During maximal effort contractions, intense serotonin release via the raphe‐spinal pathway spills over from the somato‐dendritic compartment to activate inhibitory 5‐HT 1A receptors on the axon initial segment of motoneurons to …
View article: Antagonism of the D2 dopamine receptor enhances tremor but reduces voluntary muscle activation in humans
Antagonism of the D2 dopamine receptor enhances tremor but reduces voluntary muscle activation in humans Open