Jacopo Fumagalli
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View article: Dealing With Antibiotic Prophylaxis in Lung Transplantation in the Era of Multidrug Resistance: The Milano Algorithm
Dealing With Antibiotic Prophylaxis in Lung Transplantation in the Era of Multidrug Resistance: The Milano Algorithm Open
View article: Anesthetic gases environmental impact, anesthesiologists’ awareness, and improvement opportunities: a monocentric observational study
Anesthetic gases environmental impact, anesthesiologists’ awareness, and improvement opportunities: a monocentric observational study Open
View article: REBOA: A Device to Gain Time
REBOA: A Device to Gain Time Open
The management of trauma and emergency procedures (i.e., aneurysm repair, visceral and pelvic bleeding, and others) has undergone considerable changes due to the presence of new endovascular and mini-invasive approaches, which have supplan…
View article: Dealing with Antibiotic Prophylaxis in Lung Transplantation in the Era of Multi-Drug Resistance: The Milano Algorithm
Dealing with Antibiotic Prophylaxis in Lung Transplantation in the Era of Multi-Drug Resistance: The Milano Algorithm Open
View article: Ventilation during extracorporeal gas exchange in acute respiratory distress syndrome
Ventilation during extracorporeal gas exchange in acute respiratory distress syndrome Open
Purpose of review Accumulating evidence ascribes the benefit of extracorporeal gas exchange, at least in most severe cases, to the provision of a lung healing environment through the mitigation of ventilator-induced lung injury (VILI) risk…
View article: Regional Ventilation–Perfusion Matching by Electrical Impedance Tomography After Single Lung Transplant
Regional Ventilation–Perfusion Matching by Electrical Impedance Tomography After Single Lung Transplant Open
Single lung transplantation (LUTX) can be the last therapeutic option for a growing cohort of patients suffering from end-stage respiratory failure. Postoperative ventilatory management of single LUTX recipients is challenged by the coexis…
View article: Incidence, microbiological and immunological characteristics of ventilator-associated pneumonia assessed by bronchoalveolar lavage and endotracheal aspirate in a prospective cohort of COVID-19 patients: CoV-AP study
Incidence, microbiological and immunological characteristics of ventilator-associated pneumonia assessed by bronchoalveolar lavage and endotracheal aspirate in a prospective cohort of COVID-19 patients: CoV-AP study Open
View article: Lung Transplantation From Controlled and Uncontrolled Donation After Circulatory Death (DCD) Donors With Long Ischemic Times Managed by Simple Normothermic Ventilation and Ex-Vivo Lung Perfusion Assessment
Lung Transplantation From Controlled and Uncontrolled Donation After Circulatory Death (DCD) Donors With Long Ischemic Times Managed by Simple Normothermic Ventilation and Ex-Vivo Lung Perfusion Assessment Open
Donation after cardiac death (DCD) donors are still subject of studies. In this prospective cohort trial, we compared outcomes after lung transplantation (LT) of subjects receiving lungs from DCD donors with those of subjects receiving lun…
View article: Snowmass Theory Frontier: Astrophysics and Cosmology
Snowmass Theory Frontier: Astrophysics and Cosmology Open
We summarize progress made in theoretical astrophysics and cosmology over the past decade and areas of interest for the coming decade. This Report is prepared as the TF09 "Astrophysics and Cosmology" topical group summary for the Theory Fr…
View article: Correction: Uniportal and three-portal video-assisted thoracic surgery pulmonary lobectomy for early-stage lung cancer (UNIT trial): study protocol of a single-center randomized trial
Correction: Uniportal and three-portal video-assisted thoracic surgery pulmonary lobectomy for early-stage lung cancer (UNIT trial): study protocol of a single-center randomized trial Open
View article: Limitations of arterial partial pressure of oxygen to fraction of inspired oxygen ratio for the evaluation of donor lung function
Limitations of arterial partial pressure of oxygen to fraction of inspired oxygen ratio for the evaluation of donor lung function Open
Background Evaluation of donor lung function relies on the arterial oxygen partial pressure to inspired oxygen fraction ratio (PaO 2 /FiO 2 ) measurement. Hemodynamic, metabolic derangements, and therapeutic intervention occurring during b…
View article: Lung Biomolecular Profile and Function of Grafts from Donors after Cardiocirculatory Death with Prolonged Donor Warm Ischemia Time
Lung Biomolecular Profile and Function of Grafts from Donors after Cardiocirculatory Death with Prolonged Donor Warm Ischemia Time Open
The acceptable duration of donor warm ischemia time (DWIT) after cardiocirculatory death (DCD) is still debated. We analyzed the biomolecular profile and function during ex vivo lung perfusion (EVLP) of DCD lungs and their correlation with…
View article: Detecting primordial features with LISA
Detecting primordial features with LISA Open
Oscillations in the frequency profile of the stochastic gravitational wave background are a characteristic prediction of small-scale features during inflation. In this paper we present a first investigation of the detection prospects of su…
View article: Pleural Pressure Targeted Positive Airway Pressure Improves Cardiopulmonary Function in Spontaneously Breathing Patients With Obesity
Pleural Pressure Targeted Positive Airway Pressure Improves Cardiopulmonary Function in Spontaneously Breathing Patients With Obesity Open
View article: High Pleural Pressures in Class III Obesity Prevented Hemodynamic Collapse and Alveolar Overdistension
High Pleural Pressures in Class III Obesity Prevented Hemodynamic Collapse and Alveolar Overdistension Open
View article: Uniportal and three-portal video-assisted thoracic surgery pulmonary lobectomy for early-stage lung cancer (UNIT trial): study protocol of a single-center randomized trial
Uniportal and three-portal video-assisted thoracic surgery pulmonary lobectomy for early-stage lung cancer (UNIT trial): study protocol of a single-center randomized trial Open
View article: Uni-portal and three-portal video-assisted thoracic surgery pulmonary lobectomy for early stage lung cancer (UNIT trial): study protocol of a single-center randomized trial
Uni-portal and three-portal video-assisted thoracic surgery pulmonary lobectomy for early stage lung cancer (UNIT trial): study protocol of a single-center randomized trial Open
Background Video-assisted thoracoscopic surgery (VATS) lobectomy is currently the recommended approach for treating early-stage non-small cell lung cancer (NSCLC). Different VATS approaches have been proposed so far, and the actual advanta…
View article: High Pleural Pressure Prevents Alveolar Overdistension and Hemodynamic Collapse in Acute Respiratory Distress Syndrome with Class III Obesity. A Clinical Trial
High Pleural Pressure Prevents Alveolar Overdistension and Hemodynamic Collapse in Acute Respiratory Distress Syndrome with Class III Obesity. A Clinical Trial Open
Rationale: Obesity is characterized by elevated pleural pressure (Ppl) and worsening atelectasis during mechanical ventilation in patients with acute respiratory distress syndrome (ARDS).Objectives: To determine the effects o…
View article: Early pulmonary function and mid‐term outcome in lung transplantation after<i>ex‐vivo</i>lung perfusion – a single‐center, retrospective, observational, cohort study
Early pulmonary function and mid‐term outcome in lung transplantation after<i>ex‐vivo</i>lung perfusion – a single‐center, retrospective, observational, cohort study Open
Outcomes after transplantation of lungs (LuTX) treated with ex-vivo lung perfusion (EVLP) are debated. In a single-center 8 years of retrospective analysis, we compared: donors' and recipients' characteristics, gas exchange and lung mechan…
View article: A lung rescue team improves survival in obesity with acute respiratory distress syndrome
A lung rescue team improves survival in obesity with acute respiratory distress syndrome Open
View article: Lung Recruitment in Obese Patients with Acute Respiratory Distress Syndrome
Lung Recruitment in Obese Patients with Acute Respiratory Distress Syndrome Open
Editor’s Perspective What We Already Know about This Topic Obesity increases the propensity to atelectasis in acute respiratory distress syndrome, but the optimal approach to reversing this atelectasis is uncertain What This Article Tells …
View article: Inflammation and primary graft dysfunction after lung transplantation: CT-PET findings
Inflammation and primary graft dysfunction after lung transplantation: CT-PET findings Open
Compared to healthy lungs, all the grafts showed increased [18F]FDG uptake rate, but there were no differences between patients who developed PGD and patients who did not. Of note, the PGD patients showed a worse inflation status of lungs …
View article: Hyaluronan in acute respiratory distress syndrome (ARDS): simply a biomarker or a deeper insight into ARDS mechanisms?
Hyaluronan in acute respiratory distress syndrome (ARDS): simply a biomarker or a deeper insight into ARDS mechanisms? Open
Acute respiratory distress syndrome (ARDS) affects a large number of patients admitted to the intensive care unit, it’s usually associated with multiple organ dysfunctions and mortality rate is very high (≈40%) (1).
View article: What does the Acute Respiratory Distress Syndrome trial (ART) teach us?—it is time for precision medicine and precision trials in critical care!
What does the Acute Respiratory Distress Syndrome trial (ART) teach us?—it is time for precision medicine and precision trials in critical care! Open
Acute respiratory distress syndrome (ARDS) affects a remarkable proportion of patients admitted to the intensive care unit (ICU) and according to a recent international survey, mortality attributable to ARDS remains high (≈40%) (1).