Jacquelyn Freund
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View article: IL‐15 and CD155 expression regulate LAT expression in murine DNAM1 <sup>+</sup> NK cells, enhancing their effectors functions
IL‐15 and CD155 expression regulate LAT expression in murine DNAM1 <sup>+</sup> NK cells, enhancing their effectors functions Open
NK cells are innate immune cells characterized by their ability to spontaneously lyse tumor and virally infected cells. We have recently demonstrated that IL‐15‐sufficient DC regulate NK cell effector functions in mice. Here, we establishe…
View article: Regulation of Natural Killer Cell Development and Function by Activating Receptor Signaling Pathways
Regulation of Natural Killer Cell Development and Function by Activating Receptor Signaling Pathways Open
Natural killer (NK) cells are lymphocytes of the innate immune system that recognize and eliminate virally infected and transformed cells through their release of cytotoxic granules and production of inflammatory cytokines. The balance of …
View article: Correction: Activating Receptor Signals Drive Receptor Diversity in Developing Natural Killer Cells
Correction: Activating Receptor Signals Drive Receptor Diversity in Developing Natural Killer Cells Open
[This corrects the article DOI: 10.1371/journal.pbio.1002526.].
View article: Activating Receptor Signals Drive Receptor Diversity in Developing Natural Killer Cells
Activating Receptor Signals Drive Receptor Diversity in Developing Natural Killer Cells Open
It has recently been appreciated that NK cells exhibit many features reminiscent of adaptive immune cells. Considerable heterogeneity exists with respect to the ligand specificity of individual NK cells and as such, a subset of NK cells ca…