Philippe Chanson
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View article: Pegvisomant in managing comorbidities of acromegaly: a review
Pegvisomant in managing comorbidities of acromegaly: a review Open
International audience
View article: SUN-405 Crinecerfont Shows Favorable Trends in Improving Weight-Related Outcomes in Adults With Classic Congenital Adrenal Hyperplasia: 1-Year Results From the CAHtalyst™ Adult Study
SUN-405 Crinecerfont Shows Favorable Trends in Improving Weight-Related Outcomes in Adults With Classic Congenital Adrenal Hyperplasia: 1-Year Results From the CAHtalyst™ Adult Study Open
Disclosure: I. Bancos: None. H. Falhammar: None. J. Young: None. R. Pivonello: Received research funding from Corcept Therapeutics, Neurocrine Biosciences, Recordati AG, Spruce Bioscience and Xeris Pharmaceuticals (Strongbridge Biopharma),…
View article: <scp>IMPROVE</scp> 2023: The 2nd International Meeting on Pathway‐Related Obesity: Vision & Evidence
<span>IMPROVE</span> 2023: The 2nd International Meeting on Pathway‐Related Obesity: Vision & Evidence Open
A total of 150 clinicians and researchers representing 19 countries came together in person and online to participate in the highly anticipated 2nd International Meeting on Pathway‐Related Obesity: Vision & Evidence (IMPROVE), held on 13–1…
View article: Reassessing the role of the p.(Arg304Gln) missense <i>AIP</i> variant in pituitary tumorigenesis
Reassessing the role of the p.(Arg304Gln) missense <i>AIP</i> variant in pituitary tumorigenesis Open
Objective Heterozygous germline loss-of-function variants in AIP are associated with young-onset growth hormone and/or prolactin-secreting pituitary tumours. However, the pathogenic role of the c.911G > A; p.(Arg304Gln) (R304Q) AIP vari…
View article: Menopause Has a Beneficial Influence on the Evolution of Prolactinomas. A Study of 99 Patients
Menopause Has a Beneficial Influence on the Evolution of Prolactinomas. A Study of 99 Patients Open
Context Menopause is thought to have beneficial effects in women with prolactinoma, potentially offering a higher chance for successful dopamine agonist (DA) withdrawal. However, strong evidence supporting this remains limited. Objective T…
View article: Chapter 7: The different forms of primary hyperparathyroidism at different ages of life: Childhood, pregnancy, lactation, old age
Chapter 7: The different forms of primary hyperparathyroidism at different ages of life: Childhood, pregnancy, lactation, old age Open
Primary hyperparathyroidism is rare in children. A germline mutation is identified in half of all children with primary hyperparathyroidism (70% of newborns and infants, and 40% of children and adolescents). The clinical manifestations of …
View article: Mineralocorticoid axis activity and cardiac remodeling in patients with ACTH-dependent Cushing’s syndrome
Mineralocorticoid axis activity and cardiac remodeling in patients with ACTH-dependent Cushing’s syndrome Open
Background Arterial hypertension and left ventricular hypertrophy and remodeling are independent cardiovascular risk factors in patients with Cushing’s syndrome. Changes in the renin–angiotensin system and in the mineralocorticoid axis act…
View article: 9281 Menopause Has a Beneficial Influence on the Evolution of Prolactinomas: a Study in 95 Patients
9281 Menopause Has a Beneficial Influence on the Evolution of Prolactinomas: a Study in 95 Patients Open
Disclosure: S. Constantinescu: None. C. Nava: None. F. Chasseloup: None. P. Chanson: Consulting Fee; Self; Eli Lilly & Company, Recordati, Ipsen, Novo Nordisk. O. Alexopoulou: None. D.M. Maiter: Consulting Fee; Self; Ipsen, Recordati, Pfiz…
View article: 7220 Menopause Has a Beneficial Influence on the Evolution of Prolactinomas: a Study in 95 Patients
7220 Menopause Has a Beneficial Influence on the Evolution of Prolactinomas: a Study in 95 Patients Open
Disclosure: S. Constantinescu: None. C. Nava: None. F. Chasseloup: None. P. Chanson: Consulting Fee; Self; Eli Lilly & Company, Recordati, Ipsen, Novo Nordisk. O. Alexopoulou: None. D.M. Maiter: Consulting Fee; Self; Ipsen, Recordati, Pfiz…
View article: Acromegaly: Incidence, patient characteristics and treatment patterns in a 10-year nationwide retrospective hospital cohort study
Acromegaly: Incidence, patient characteristics and treatment patterns in a 10-year nationwide retrospective hospital cohort study Open
This study was the first, in a large population, to estimate the contemporary incidence and prevalence of acromegaly in non-selected patients at nationwide level in France. We found higher prevalences of complications than previously repor…
View article: Increase in Testosterone Levels and Improvement of Clinical Symptoms in Eugonadic men With a Prolactin-secreting Adenoma
Increase in Testosterone Levels and Improvement of Clinical Symptoms in Eugonadic men With a Prolactin-secreting Adenoma Open
Objective Testosterone concentrations, albeit rarely, may be in the normal range (>3.0 ng/mL) in men with a prolactin-secreting pituitary adenoma (PSPA-nt). The evolution of total, bioavailable testosterone, gonadotropin levels, and tha…
View article: Diagnosis and management of children and adult craniopharyngiomas: A French Endocrine Society/French Society for Paediatric Endocrinology & Diabetes Consensus Statement
Diagnosis and management of children and adult craniopharyngiomas: A French Endocrine Society/French Society for Paediatric Endocrinology & Diabetes Consensus Statement Open
International audience
View article: Lessons From Prospective Longitudinal Follow-up of a French APECED Cohort
Lessons From Prospective Longitudinal Follow-up of a French APECED Cohort Open
Background Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome is a rare disease caused by biallelic mutations of the AIRE gene, usually presenting with the triad hypoparathyroidism-adrenal failure-chronic mucocutaneous…
View article: Standards of Care for Medical Management of Acromegaly in Pituitary Tumor Centers of Excellence (PTCOE)
Standards of Care for Medical Management of Acromegaly in Pituitary Tumor Centers of Excellence (PTCOE) Open
Purpose: A series of consensus guidelines on medical treatment of acromegaly have been produced in the last two decades. However, little information is available on their application in clinical practice. Furthermore, international standar…
View article: Impact of exenatide on weight loss and eating behavior in adults with craniopharyngioma-related obesity: the CRANIOEXE randomized placebo-controlled trial
Impact of exenatide on weight loss and eating behavior in adults with craniopharyngioma-related obesity: the CRANIOEXE randomized placebo-controlled trial Open
Importance A major issue in the management of craniopharyngioma-related obesity (CRO) is the ineffectiveness of the current therapeutic approaches. Objective To study the efficacy of glucagon-like peptide-1 analogs compared with placebo in…
View article: Tout-Monde
Tout-Monde Open
"All-World" is a conceptual tool put forward by Martinique philosopher Édouard Glissant, through which he proposes to rethink our erratic world and our presence in it, overcoming the ideologies of borders, ghettos and globalization against…
View article: OR17-05 Lysine Demethylase KDM1A And Ectopic Expression Of GIP-Receptor In Somatotropinomas Of Patients With Paradoxical Response To Oral Glucose
OR17-05 Lysine Demethylase KDM1A And Ectopic Expression Of GIP-Receptor In Somatotropinomas Of Patients With Paradoxical Response To Oral Glucose Open
Disclosure: F. Chasseloup: None. L. Tosca: None. D. Regazzo: None. A. Proust: None. M. Hage: None. E. Kuhn: None. C. Jublanc: None. K. Mokhtari: None. S. Salenave: None. S. Gaillard: None. F. Parker: None. A. Boch: None. G. Tachdjian: None…
View article: THU059 Increased Intracellular And Extracellular Myocardial Masses On Cardiac Magnetic Resonance Imaging In Patents With Acromegaly
THU059 Increased Intracellular And Extracellular Myocardial Masses On Cardiac Magnetic Resonance Imaging In Patents With Acromegaly Open
Disclosure: P. Wolf: None. K. Bouazizi: None. N. Kachenoura: None. C. Piedvache: None. A. Gallo: None. S. Salenave: None. L. Maione: None. J. Young: None. M. Prigent: None. A. Lecoq: None. E. Kuhn: None. H. Agostini: None. S. Trabado: None…
View article: Impact of Cushing’s syndrome on the gonadotrope axis and testicular functions in men
Impact of Cushing’s syndrome on the gonadotrope axis and testicular functions in men Open
STUDY QUESTION Does Cushing’s syndrome (CS) differently affect the gonadotrope axis and testicular functions (GA/TF) according to the hypercortisolism intensity and underlying etiology? SUMMARY ANSWER Endogenous cortisol excess caused by C…