Jaden M. Wells
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View article: Pediatric CHOP Chemotherapy Acutely Disrupts Satellite-Cell Dynamics and Blunts Muscle Mass in a Sex-Specific Manner
Pediatric CHOP Chemotherapy Acutely Disrupts Satellite-Cell Dynamics and Blunts Muscle Mass in a Sex-Specific Manner Open
Pediatric cancer survival now exceeds 85 percent owing, in part, advances and use of combination chemotherapy treatments such as CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone). Despite its efficacy, CHOP may cause delete…
View article: The life and times of cellular senescence in skeletal muscle: friend or foe for homeostasis and adaptation?
The life and times of cellular senescence in skeletal muscle: friend or foe for homeostasis and adaptation? Open
There is evidence to suggest that senescent “zombie” cells may or may not accrue in aging skeletal muscle. When muscle is perturbed regardless of age, senescent-like cells do appear, and the benefits of removing them could be age-dependent…