Ho Jae Han
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View article: Outcomes of 87 small‐breed dogs surgically treated for Chiari‐like malformation and syringomyelia
Outcomes of 87 small‐breed dogs surgically treated for Chiari‐like malformation and syringomyelia Open
Objective To report the outcomes of titanium mesh (TM) cranioplasty without polymethylmethacrylate (PMMA), incorporating a deliberate gap between the foramen magnum decompression (FMD) surface and the TM, in small‐breed dogs with Chiari‐li…
View article: Combined intra- and extracapsular stabilization for CCL rupture in a toy-breed dog: a case report
Combined intra- and extracapsular stabilization for CCL rupture in a toy-breed dog: a case report Open
Cranial cruciate ligament (CrCL) rupture is a frequent orthopedic condition leading to hindlimb dysfunction in dogs. While tibial plateau leveling osteotomy (TPLO) has become the predominant surgical choice in large breeds, its use in toy-…
View article: Disarming Salmonella virulence with 32H-hilE anti-virulence bacteriophage
Disarming Salmonella virulence with 32H-hilE anti-virulence bacteriophage Open
As the development of new antibiotics struggles with the continuous emergence of drug-resistant bacteria, targeting bacterial virulence factors instead of viability has been proposed as one of the alternative approaches to combat the patho…
View article: A 3D <i>Fusarium</i> keratitis model reveals isolate-specific adhesion and invasion properties in the <i>Fusarium solani</i> species complex
A 3D <i>Fusarium</i> keratitis model reveals isolate-specific adhesion and invasion properties in the <i>Fusarium solani</i> species complex Open
Members of the Fusarium solani species complex (FSSC) are major causes of keratitis in humans. The underlying mechanisms leading to this disease are not well understood, partially due to the absence of more complex in vitro infection model…
View article: Pathogenicity and contact transmissibility of clade IIb MPXV in African dormice
Pathogenicity and contact transmissibility of clade IIb MPXV in African dormice Open
The global outbreak of monkeypox virus (MPXV) in 2022 raised widespread scientific concern regarding potential changes in its biological characteristics. In this study, we conducted research on the pathogenicity and transmissibility of the…
View article: Abnormal Vibration Identification of Metro Tunnels on the Basis of the Spatial Correlation of Dynamic Strain from Dense Measurement Points of Distributed Sensing Optical Fibers
Abnormal Vibration Identification of Metro Tunnels on the Basis of the Spatial Correlation of Dynamic Strain from Dense Measurement Points of Distributed Sensing Optical Fibers Open
The failure to accurately identify abnormal vibrations in protected metro areas is a serious threat to the operational safety of metro tunnels and trains, and there is currently no suitable method for effectively improving the accuracy of …
View article: Zerumbone Attenuates Lipopolysaccharide‐Induced Acute Lung Injury by Suppressing the <scp>NLRP</scp>3/Caspase‐1/<scp>GSDMD</scp> Signalling Pathway
Zerumbone Attenuates Lipopolysaccharide‐Induced Acute Lung Injury by Suppressing the <span>NLRP</span>3/Caspase‐1/<span>GSDMD</span> Signalling Pathway Open
A cyclic sesquiterpene with 11 carbon atoms is the primary component of essential oils from the wild ginger species, Zingiber zerumbet . It exhibits pharmacological effects, including anti‐inflammatory and antioxidant properties. However, …
View article: Expert consensus regarding the clinical application of liver contrast-enhanced US with Sonazoid (Sonazoid CEUS)
Expert consensus regarding the clinical application of liver contrast-enhanced US with Sonazoid (Sonazoid CEUS) Open
Sonazoid, a combined blood pool and Kupffer-cell agent, can be specifically phagocytosed by Kupffer cells in the liver, allowing lesion detection and characterization of focal liver lesions (FLLs) at the post-vascular phase apart from the …
View article: Recovery of FAM134A-mediated ER-phagy through BRD4 inhibition alleviates ethanol-induced neurodegeneration
Recovery of FAM134A-mediated ER-phagy through BRD4 inhibition alleviates ethanol-induced neurodegeneration Open
Endoplasmic reticulum (ER) stress is a major contributor to ethanol-induced neurodegeneration. ER-phagy, the selective elimination of specific ER domains, has emerged as a protective mechanism against ER stress. However, its regulation in …
View article: A condition diagnosis method for subway track structures employing distributed optical fiber sensing
A condition diagnosis method for subway track structures employing distributed optical fiber sensing Open
View article: A practical approach for the stable isolation and cultivation of chicken gonadal primordial germ cells with mitotically inactivated STO feeder cells
A practical approach for the stable isolation and cultivation of chicken gonadal primordial germ cells with mitotically inactivated STO feeder cells Open
Objective: Establishing chicken primordial germ cells (PGCs) in vitro is critical for producing genetically modified (GM) chickens. Efficient and reliable isolation and cultivation of PGCs remain significant challenges in advancing avian g…
View article: Restoration of Miro1’s N-terminal GTPase function alleviates prenatal stress-induced mitochondrial fission via Drp1 modulation
Restoration of Miro1’s N-terminal GTPase function alleviates prenatal stress-induced mitochondrial fission via Drp1 modulation Open
Background Prenatal stress exposure irreversibly impairs mitochondrial dynamics, including mitochondrial trafficking and morphology in offspring, leading to neurodevelopmental and neuropsychiatric disorders in adulthood. Thus, understandin…
View article: SWIPTNet: A Unified Deep Learning Framework for SWIPT based on GNN and Transfer Learning
SWIPTNet: A Unified Deep Learning Framework for SWIPT based on GNN and Transfer Learning Open
This paper investigates the deep learning based approaches for simultaneous wireless information and power transfer (SWIPT). The quality-of-service (QoS) constrained sum-rate maximization problems are, respectively, formulated for power-sp…
View article: Identification and expression analysis of P-type ATPase IIIA subfamily in Puccinia Striiformis f. sp. tritici
Identification and expression analysis of P-type ATPase IIIA subfamily in Puccinia Striiformis f. sp. tritici Open
Our results indicate that the PMA gene family in the CYR34 strain comprises six PMA genes, which are crucial for managing temperature stress and pathogen infection, and exhibit a distinctive splicing pattern. This study not only identifies…
View article: Selective activation of FZD2 and FZD7 reveals non-redundant function during mesoderm differentiation
Selective activation of FZD2 and FZD7 reveals non-redundant function during mesoderm differentiation Open
During gastrulation, Wnt-β-catenin signaling dictates lineage bifurcation generating different mesoderm cell types. However, the specific role of Wnt receptors in mesoderm specification remains elusive. Using selective Frizzled (FZD) and L…
View article: Anti-aging strategies for dogs
Anti-aging strategies for dogs Open
View article: Lifestyle factors affecting aging and healthspan in dogs and cats
Lifestyle factors affecting aging and healthspan in dogs and cats Open
View article: Toward a New Era of Companion Animal Longevity and Well-Being
Toward a New Era of Companion Animal Longevity and Well-Being Open
View article: Study on the Long-term Mechanism and Realization Path of Rural Sports Events to Promote Comprehensive Rural Revitalization
Study on the Long-term Mechanism and Realization Path of Rural Sports Events to Promote Comprehensive Rural Revitalization Open
The purpose of this paper is to discuss the role of rural sports events in promoting the comprehensive revitalization of the countryside and its long-term mechanism and realization path. With the implementation of China's rural revitalizat…
View article: Study on Mechanism Construction and Path Innovation of Sports and Tourism Integration for Comprehensive Rural Revitalization in Guangdong, Hong Kong and Macao Greater Bay Area
Study on Mechanism Construction and Path Innovation of Sports and Tourism Integration for Comprehensive Rural Revitalization in Guangdong, Hong Kong and Macao Greater Bay Area Open
With the rapid development of China's economy, the strategy of rural revitalization has become an important initiative to achieve balanced development of urban and rural areas. As an important economic region at the national strategic leve…
View article: Genome-wide phenotypic profiling of transcription factors and identification of novel targets to control the virulence of <i>Vibrio vulnificus</i>
Genome-wide phenotypic profiling of transcription factors and identification of novel targets to control the virulence of <i>Vibrio vulnificus</i> Open
For successful infection, the life-threatening pathogen Vibrio vulnificus elaborately regulates the expression of survival and virulence genes using various transcription factors (TFs). In this study, a library of the V. vulnificus mutants…
View article: Functional profiling of murine glioma models highlights targetable immune evasion phenotypes
Functional profiling of murine glioma models highlights targetable immune evasion phenotypes Open
View article: Functional profiling of murine glioma models highlights targetable immune evasion phenotypes
Functional profiling of murine glioma models highlights targetable immune evasion phenotypes Open
Cancer intrinsic immune evasion mechanisms and pleiotropy represent a barrier to effective translation of cancer immunotherapy. This is acutely apparent for certain highly fatal cancers such as high-grade gliomas and glioblastomas. In this…
View article: The potential role of gut microbiota-derived metabolites as regulators of metabolic syndrome-associated mitochondrial and endolysosomal dysfunction in Alzheimer’s disease
The potential role of gut microbiota-derived metabolites as regulators of metabolic syndrome-associated mitochondrial and endolysosomal dysfunction in Alzheimer’s disease Open
View article: Randomized, double-blind, placebo-controlled trial of aripiprazole oral solution in children and adolescents with Tourette’s disorder
Randomized, double-blind, placebo-controlled trial of aripiprazole oral solution in children and adolescents with Tourette’s disorder Open
Background Aripiprazole is the most frequently recommended antipsychotic for the treatment of tics in children and adolescents with Tourette’s disorder (TD). However, to date, a randomized controlled trial for aripiprazole oral solution ha…
View article: Analysis of genetic variations of a recombinant strain derived from the three lineages of porcine reproductive and respiratory syndrome virus-2
Analysis of genetic variations of a recombinant strain derived from the three lineages of porcine reproductive and respiratory syndrome virus-2 Open
Since the rise of the porcine reproductive and respiratory syndrome virus (PRRSV) in China, gene mutations have frequently occurred. To understand the current prevalence and evolution of PRRSV in Shandong Province, 1,528 samples suspected …
View article: Positive effects of parent–child group emotional regulation and resilience training on nonsuicidal self-injury behavior in adolescents: a quasi-experimental study
Positive effects of parent–child group emotional regulation and resilience training on nonsuicidal self-injury behavior in adolescents: a quasi-experimental study Open
Background Nonsuicidal self-injury (NSSI) among adolescents is a growing global concern. However, effective interventions for treating NSSI are limited. Method A 36-week quasi-experimental study design of parent–child group resilience trai…
View article: Sodium butyrate ameliorates high glucose-suppressed neuronal mitophagy by restoring PRKN expression via inhibiting the RELA-HDAC8 complex
Sodium butyrate ameliorates high glucose-suppressed neuronal mitophagy by restoring PRKN expression via inhibiting the RELA-HDAC8 complex Open
Damaged mitochondria accumulation in diabetes is one of the main features that contribute to increased incidence of cognitive impairment by inducing apoptosis. Butyrate is a major metabolite produced by microbiota that has neuroprotective …
View article: Knowledge, attitude, and practice of patients with major depressive disorder on exercise therapy
Knowledge, attitude, and practice of patients with major depressive disorder on exercise therapy Open
Background This study aimed to explore the knowledge, attitude, and practice (KAP) toward exercise therapy of patients with major depressive disorder (MDD). Methods This cross-sectional study was conducted at the First Hospital of Shanxi M…
View article: Esketamine use is associated with shortened postoperative hospital stay in patients after knee arthroscopic surgery: a propensity score–matched cohort study
Esketamine use is associated with shortened postoperative hospital stay in patients after knee arthroscopic surgery: a propensity score–matched cohort study Open