Jae‐Hyung Jang
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View article: Estradiol rescues male hydroxyl radical-mediated Charcot-Marie-Tooth 2Z by Morc2a stabilization through autophagy inhibition in a murine model
Estradiol rescues male hydroxyl radical-mediated Charcot-Marie-Tooth 2Z by Morc2a stabilization through autophagy inhibition in a murine model Open
Charcot–Marie–Tooth disease type 2Z (CMT2Z) is an inherited axonal neuropathy caused by haploinsufficiency of microrchidia CW-type zinc finger protein 2 ( MORC2 ), which leads to elevated hydroxyl radical levels, reduced ATPase activity, a…
View article: Embodied Auxetic Intelligence in a Glove‐Type Wearable Haptic Interface Connecting Humans to Robots and the Metaverse (Adv. Funct. Mater. 34/2025)
Embodied Auxetic Intelligence in a Glove‐Type Wearable Haptic Interface Connecting Humans to Robots and the Metaverse (Adv. Funct. Mater. 34/2025) Open
View article: Embodied Auxetic Intelligence in a Glove‐Type Wearable Haptic Interface Connecting Humans to Robots and the Metaverse
Embodied Auxetic Intelligence in a Glove‐Type Wearable Haptic Interface Connecting Humans to Robots and the Metaverse Open
The versatility of fingers stems from their ability to interact with surroundings by taking poses, performing various grasping modes, and making dynamic bending motions. However, conventional glove‐type wearable interfaces often fail to fu…
View article: Exploring Perception Types of Humanities Job Seekers in Employment Preparation: Implications for Career Guidance
Exploring Perception Types of Humanities Job Seekers in Employment Preparation: Implications for Career Guidance Open
This study uses Q methodology to examine the perception types of humanities majors during their employment preparation process. With the rapid advancement of artificial intelligence (AI) and automation technologies, traditional career path…
View article: In vivo neural regeneration via AAV-NeuroD1 gene delivery to astrocytes in neonatal hypoxic-ischemic brain injury
In vivo neural regeneration via AAV-NeuroD1 gene delivery to astrocytes in neonatal hypoxic-ischemic brain injury Open
View article: Pastable, Adhesive, Injectable, Nanofibrous, and Tunable (PAINT) Biphasic Hybrid Matrices as Versatile Therapeutic Carriers
Pastable, Adhesive, Injectable, Nanofibrous, and Tunable (PAINT) Biphasic Hybrid Matrices as Versatile Therapeutic Carriers Open
A critical challenge in many pharmaceutical fields is developing versatile adjuvant devices that can reduce the off-target delivery of therapeutic materials to target lesions. Herein, a biphasic hybrid fibrous system that can manipulate th…
View article: Soft subdermal implant capable of wireless battery charging and programmable controls for applications in optogenetics
Soft subdermal implant capable of wireless battery charging and programmable controls for applications in optogenetics Open
View article: TNF-α Pretreatment Improves the Survival and Function of Transplanted Human Neural Progenitor Cells Following Hypoxic-Ischemic Brain Injury
TNF-α Pretreatment Improves the Survival and Function of Transplanted Human Neural Progenitor Cells Following Hypoxic-Ischemic Brain Injury Open
Neural progenitor cells (NPCs) therapy offers great promise in hypoxic-ischemic (HI) brain injury. However, the poor survival of implanted NPCs in the HI host environment limits their therapeutic effects. Tumor necrosis factor-alpha (TNF-α…
View article: Glial Cell Line-derived Neurotrophic Factor-overexpressing Human Neural Stem/Progenitor Cells Enhance Therapeutic Efficiency in Rat with Traumatic Spinal Cord Injury
Glial Cell Line-derived Neurotrophic Factor-overexpressing Human Neural Stem/Progenitor Cells Enhance Therapeutic Efficiency in Rat with Traumatic Spinal Cord Injury Open
Spinal cord injury (SCI) causes axonal damage and demyelination, neural cell death, and comprehensive tissue loss, resulting in devastating neurological dysfunction. Neural stem/progenitor cell (NSPCs) transplantation provides therapeutic …
View article: Safety and efficacy evaluations of an adeno-associated virus variant for preparing IL10-secreting human neural stem cell-based therapeutics
Safety and efficacy evaluations of an adeno-associated virus variant for preparing IL10-secreting human neural stem cell-based therapeutics Open
View article: Enhanced Cell Adhesion on a Nano-Embossed, Sticky Surface Prepared by the Printing of a DOPA-Bolaamphiphile Assembly Ink
Enhanced Cell Adhesion on a Nano-Embossed, Sticky Surface Prepared by the Printing of a DOPA-Bolaamphiphile Assembly Ink Open
View article: Inverted Quasi‐Spherical Droplets on Polydopamine–TiO<sub>2</sub> Substrates for Enhancing Gene Delivery
Inverted Quasi‐Spherical Droplets on Polydopamine–TiO<sub>2</sub> Substrates for Enhancing Gene Delivery Open
Devising efficient gene delivery systems is crucial to enhancing the therapeutic efficacy of gene–cell therapy approaches. Herein, inverted quasi‐spherical (iQS) droplet systems, which enhance gene delivery efficiencies by reducing the pat…
View article: Significant Attenuation of Aden-associate Virus Gene Expression by Catechol-conjugated Heparin Surface Coating
Significant Attenuation of Aden-associate Virus Gene Expression by Catechol-conjugated Heparin Surface Coating Open
일반적으로, 화학 물리적 변성이 수반되는 멸균방법을 적용하지 못하는 경우 필터여과에 의한 멸균 방법을 주로 사용한다. 하지만 바이러스의 경우 100 nm의 작은 크기로 인해 박테리아 제거에 사용되는 필터여과에 의한 멸균 방법을 적용하기가 어렵다. 본 논문에서는 화학 물리적 변성 없이 바이러스를 비활성화하는 물질 개발을 위하여, 카테콜기가 도입된 헤파린 고분자(Hep-C)를 합성하였다. Hep-C의 바이러스 비활성화 효과를 알…
View article: Salt-Induced Electrospun Patterned Bundled Fibers for Spatially Regulating Cellular Responses
Salt-Induced Electrospun Patterned Bundled Fibers for Spatially Regulating Cellular Responses Open
Implementing patterned fibrous matrices can offer a highly valuable platform for spatially orchestrating hierarchical cellular constructs, specifically for neural engineering approaches, in which striated alignment or directional growth of…
View article: Robust Optimal Design of Tail Geometry for Stable Water-running Robots
Robust Optimal Design of Tail Geometry for Stable Water-running Robots Open
Biomimetics involves the design of robotic platforms inspired from living creatures to achieve efficient operation under environmental conditions. A development within biomimetics involves investigating the function of a tail and applying …
View article: Sliding Fibers: Slidable, Injectable, and Gel-like Electrospun Nanofibers as Versatile Cell Carriers
Sliding Fibers: Slidable, Injectable, and Gel-like Electrospun Nanofibers as Versatile Cell Carriers Open
Designing biomaterial systems that can mimic fibrous, natural extracellular matrix is crucial for enhancing the efficacy of various therapeutic tools. Herein, a smart technology of three-dimensional electrospun fibers that can be injected …
View article: Polydopamine‐Decorated Sticky, Water‐Friendly, Biodegradable Polycaprolactone Cell Carriers
Polydopamine‐Decorated Sticky, Water‐Friendly, Biodegradable Polycaprolactone Cell Carriers Open
A bioinspired adhesive material, polydopamine (pDA), was employed as an interfacial glue to stably immobilize human neural stem cells (hNSCs) on the external surface of biodegradable polycaprolactone (PCL) microspheres, thereby serving as …