Je Hyeong Kim
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View article: High-efficiency multi-mode linear battery charger with adaptive current sensor for multiple energy harvesting systems
High-efficiency multi-mode linear battery charger with adaptive current sensor for multiple energy harvesting systems Open
With the increasing integration of energy-harvesting systems into low-power applications, the need for efficient and accurate battery-charging circuits has become critical. In such systems, fluctuating energy sources affect the stability a…
View article: DHRS13 suppresses differentiation and mitophagy in glioma via retinoic acid and mitochondrial reactive oxygen species
DHRS13 suppresses differentiation and mitophagy in glioma via retinoic acid and mitochondrial reactive oxygen species Open
To elucidate the complex interplay of undifferentiated cancer cells in malignancy, we focus on the crucial mechanisms that maintain the undifferentiated state of cancer stem-like cells, which drive tumor growth and therapy resistance. Here…
View article: Closed intensive care units and sepsis patient outcomes: a secondary analysis of data from a multicenter prospective observational study in South Korea
Closed intensive care units and sepsis patient outcomes: a secondary analysis of data from a multicenter prospective observational study in South Korea Open
Background: Sepsis is a leading cause of intensive care unit (ICU) admission. However, few studies have evaluated how the ICU model affects the outcomes of patients with sepsis. Methods: This post hoc analysis of data from the Management o…
View article: Genome wide interaction study of genetic variants associated with lung function decline
Genome wide interaction study of genetic variants associated with lung function decline Open
View article: Clinical Characteristics of Fever After Extracorporeal Membrane Oxygenation Decannulation: Differentiating Infectious from Non-Infectious Causes of Fever and Their Impact on Outcomes
Clinical Characteristics of Fever After Extracorporeal Membrane Oxygenation Decannulation: Differentiating Infectious from Non-Infectious Causes of Fever and Their Impact on Outcomes Open
Background: A fever is an important sign that affects patient outcomes with various etiologies in the post-decannulation period of extracorporeal membrane oxygenation (ECMO); however, the cause is not fully understood. This study aimed to …
View article: Polyhexamethylene Guanidine Phosphate Induces Restrictive Ventilation Defect and Alters Lung Resistance and Compliance in Mice
Polyhexamethylene Guanidine Phosphate Induces Restrictive Ventilation Defect and Alters Lung Resistance and Compliance in Mice Open
Polyhexamethylene guanidine phosphate (PHMG-p), a major ingredient of humidifier disinfectants, is known to induce inflammation, interstitial pneumonitis, and fibrosis in the lungs. While its histopathologic toxicities have been studied in…
View article: Identification of novel COPD susceptibility genes using a genome-wide interaction study
Identification of novel COPD susceptibility genes using a genome-wide interaction study Open
Some genetic variants are associated with chronic obstructive pulmonary disease (COPD), but genetic susceptibility for lung function decline has not been studied in the general population. We investigated the genetic susceptibility-associa…
View article: Prognostic evaluation of quick sequential organ failure assessment score in ICU patients with sepsis across different income settings
Prognostic evaluation of quick sequential organ failure assessment score in ICU patients with sepsis across different income settings Open
View article: Association between high platelet reactivity and early stent thrombosis in patients with drug-eluting stent implantation
Association between high platelet reactivity and early stent thrombosis in patients with drug-eluting stent implantation Open
Background Stent thrombosis (ST) is a potentially fatal complication after percutaneous coronary intervention (PCI). The association between P2Y12 reaction unit (PRU) level and stent thrombosis occurrence is not fully elucidated. Methods B…
View article: Interplay among proton pump inhibitors, platelet reactivity and CYP2C19 genotyping in clopidogrel-treated patients after drug-eluting stent implantation
Interplay among proton pump inhibitors, platelet reactivity and CYP2C19 genotyping in clopidogrel-treated patients after drug-eluting stent implantation Open
Background Several published data suggested that concomitant use of clopidogrel and proton pump inhibitors (PPIs) is associated with reduced antiplatelet efficacy of clopidogrel and increased adverse clinical outcomes. We sought to evaluat…
View article: Regular supervised exercise training improves endothelial function, early atherosclerosis, arterial stiffness and endothelial progenitor cells in PCI patients
Regular supervised exercise training improves endothelial function, early atherosclerosis, arterial stiffness and endothelial progenitor cells in PCI patients Open
Backgrounds A disrupted balance between endothelial injury and repair induces endothelial dysfunction and endothelial progenitor cells (EPC) augment vascular repair. So, exercise improves endothelial function through increased numbers of E…
View article: 101 Atopic dermatitis and psoriasis overlap: A new disease entity defined by spatial molecular analysis of atopic dermatitis and psoriasis
101 Atopic dermatitis and psoriasis overlap: A new disease entity defined by spatial molecular analysis of atopic dermatitis and psoriasis Open
View article: COVID-19 versus Other Disease Etiologies as the Cause of ARDS in Patients Necessitating Venovenous Extracorporeal Membrane Oxygenation—A Comparison of Patients’ Data during the Three Years of the COVID-19 Pandemic
COVID-19 versus Other Disease Etiologies as the Cause of ARDS in Patients Necessitating Venovenous Extracorporeal Membrane Oxygenation—A Comparison of Patients’ Data during the Three Years of the COVID-19 Pandemic Open
Considering the characteristics of coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS), we compared the clinical course and outcomes of patients with ARDS who received venovenous extracorporeal membrane oxygenati…
View article: Identification of Novel COPD Susceptibility Genes: A Genome-wide Interaction Study
Identification of Novel COPD Susceptibility Genes: A Genome-wide Interaction Study Open
Background: Variants of some genes are associated with chronic obstructive pulmonary disease (COPD). However, genetic susceptibility for lung function decline in the general population remains unclear. Here, we investigated the genetic sus…
View article: P-737 Progress in non-invasive embryo assessment with cell-free nucleic acids in blastocoel fluid
P-737 Progress in non-invasive embryo assessment with cell-free nucleic acids in blastocoel fluid Open
Study question Can cell-free nucleic acids (cfDNA) from blastocoel fluid (BF) after a trophectoderm (TE) biopsy be used as a non-invasive sample type to assess embryos? Summary answer Both BF and spent media carry comparable, highly fragme…
View article: Seven-day and In-hospital Mortality According to Left and Right Ventricular Dysfunction in Patients With Septic Shock
Seven-day and In-hospital Mortality According to Left and Right Ventricular Dysfunction in Patients With Septic Shock Open
Fluctuation of both ventricular function was common in septic shock. Seven-day mortality of patients with septic shock was related to GLS, whereas in-hospital mortality of 7-day survivors was related to TAPSE, not to GLS.
View article: The Profile of Early Sedation Depth and Clinical Outcomes of Mechanically Ventilated Patients in Korea
The Profile of Early Sedation Depth and Clinical Outcomes of Mechanically Ventilated Patients in Korea Open
In many Korean ICUs, early deep sedation was highly prevalent in mechanically ventilated patients and was associated with delayed extubation, but not prolonged ICU stay or in-hospital death.
View article: The long-term cardiac events after coronary bifurcation stenting with second-generation drug-eluting stents in elderly patients are comparable to those of younger patients
The long-term cardiac events after coronary bifurcation stenting with second-generation drug-eluting stents in elderly patients are comparable to those of younger patients Open
Background Elderly patients undergoing percutaneous coronary intervention (PCI) generally have a high risk of adverse clinical outcomes. We investigated the long-term clinical impact of PCI on coronary bifurcation disease in elderly patien…
View article: The differential effects of antihypertensive drugs on central blood pressure: nebivolol versus telmisartan (ATD-CBP)
The differential effects of antihypertensive drugs on central blood pressure: nebivolol versus telmisartan (ATD-CBP) Open
Background Central blood pressure and central pulse pressure have a better correlation with the risk of cardiovascular disease compared to those of peripheral measurement. In a previous study, a second-generation beta-blocker showed poor C…
View article: Sodium bicarbonate buffer for weaning from venovenous extracorporeal membrane oxygenation in patients with hypercapnic respiratory failure and acute renal failure
Sodium bicarbonate buffer for weaning from venovenous extracorporeal membrane oxygenation in patients with hypercapnic respiratory failure and acute renal failure Open
Although the routine use of alkali buffer is not recommended in patients with respiratory acidosis, some patients may benefit from its administration. A 42-year-old man was treated with venovenous extracorporeal membrane oxygenation (VV-EC…
View article: Comparison of clinical characteristics and hospital mortality in critically ill patients without COVID-19 before and during the COVID-19 pandemic: a multicenter, retrospective, propensity score-matched study
Comparison of clinical characteristics and hospital mortality in critically ill patients without COVID-19 before and during the COVID-19 pandemic: a multicenter, retrospective, propensity score-matched study Open
Background The high transmission and fatality rates of coronavirus disease 2019 (COVID-19) strain intensive care resources and affect the treatment and prognosis of critically ill patients without COVID-19. Therefore, this study evaluated …
View article: Associations between Phosphate Concentrations and Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation
Associations between Phosphate Concentrations and Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation Open
Phosphate concentrations change continuously throughout hospitalization; however, it is unclear which available phosphate measures are most clinically important for predicting hospital mortality. Therefore, we investigated phosphate concen…
View article: Poster Abstracts
Poster Abstracts Open
OBJECTIVE:We aimed to evaluate the efficacy of sodium-glucose cotransporter 2 (SGLT2) inhibitors to manage obesity in non-diabetic overweight or obese patients.METHODS: We searched PubMed, EMBASE, Web of Science, and the Cochrane Central R…
View article: An Integrated Model including the ROX Index to Predict the Success of High-Flow Nasal Cannula Use after Planned Extubation: A Retrospective Observational Cohort Study
An Integrated Model including the ROX Index to Predict the Success of High-Flow Nasal Cannula Use after Planned Extubation: A Retrospective Observational Cohort Study Open
High-flow nasal cannula (HFNC) therapy is commonly used to prevent reintubation after planned extubation. In clinical practice, there are no appropriate tools to evaluate whether HFNC therapy was successful or failed after planned extubati…
View article: Thoracomyoplasty and perioperative negative wound pressure therapy for bronchopleural fistula after trans-sternal bronchial closure
Thoracomyoplasty and perioperative negative wound pressure therapy for bronchopleural fistula after trans-sternal bronchial closure Open
View article: Guanylate-binding proteins induce apoptosis of leukemia cells by regulating MCL-1 and BAK
Guanylate-binding proteins induce apoptosis of leukemia cells by regulating MCL-1 and BAK Open
View article: Longitudinal Evaluation of the Relationship Between Low Socioeconomic Status and Incidence of Chronic Obstructive Pulmonary Disease: Korean Genome and Epidemiology Study (KoGES)
Longitudinal Evaluation of the Relationship Between Low Socioeconomic Status and Incidence of Chronic Obstructive Pulmonary Disease: Korean Genome and Epidemiology Study (KoGES) Open
In the general population, educational level of elementary school was an independent risk factor for COPD among the components comprising SES. Our results indicate that the implementation of preventive strategies for COPD in those with low…
View article: Predictive Role of Lung Injury Prediction Score in the Development of Acute Respiratory Distress Syndrome in Korea
Predictive Role of Lung Injury Prediction Score in the Development of Acute Respiratory Distress Syndrome in Korea Open
LIPS predicted the development of ARDS as diagnosed by the Berlin definition in the Korean population. LIPS provides useful information for managing patients with ARDS.
View article: Experience of augmenting critical care capacity in Daegu during COVID-19 incident in South Korea
Experience of augmenting critical care capacity in Daegu during COVID-19 incident in South Korea Open
View article: Factors Associated With Failure of High-Flow Nasal Cannula
Factors Associated With Failure of High-Flow Nasal Cannula Open
HFNC was practiced without applying reservoir or other high-flow devices before application and without appropriate arterial blood gas monitoring during HFNC therapy. HFNC failure was significantly associated with the decision by the resid…