Jae Kyung Kim
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View article: Long-Term Trends in Human Parainfluenza Virus Types 1, 2, and 3 Infection in Korea (2007–2024)
Long-Term Trends in Human Parainfluenza Virus Types 1, 2, and 3 Infection in Korea (2007–2024) Open
This study investigated the long-term trends in human parainfluenza virus (HPIV) types 1, 2, and 3 in Korea by year, age group, and season. A total of 23,284 nasopharyngeal swabs collected from patients with respiratory symptoms at a terti…
View article: Long-Term Epidemiological Trends of Human Adenovirus Infection in South Korea: A Single-Center Study (2007–2024)
Long-Term Epidemiological Trends of Human Adenovirus Infection in South Korea: A Single-Center Study (2007–2024) Open
Human adenoviruses (HAdVs; genus Mastadenovirus, family Adenoviridae) are major etiologic agents of respiratory infections, exerting a disproportionately large impact on children. However, no long-term study to date has spanned pre- and po…
View article: Epidemiological Characteristics of HSV-1 and HSV-2 in 177,599 Patients Based on PCR Testing in South Korea (2018–2022)
Epidemiological Characteristics of HSV-1 and HSV-2 in 177,599 Patients Based on PCR Testing in South Korea (2018–2022) Open
HSV-1 is associated with oral lesions and non-sexual transmission; HSV-2 is primarily transmitted through sexual contact and causes genital infections. Understanding the epidemiological dynamics of both viruses is essential for guiding tar…
View article: Eighteen Years of Human Rhinovirus Surveillance in the Republic of Korea (2007–2024): Age- and Season-Specific Trends from a Single-Center Study with Public Health Implications
Eighteen Years of Human Rhinovirus Surveillance in the Republic of Korea (2007–2024): Age- and Season-Specific Trends from a Single-Center Study with Public Health Implications Open
Human rhinovirus (HRV) is the most common cause of upper respiratory tract infections and can cause substantial morbidity in children. Because its clinical features are nonspecific, differentiation from influenza virus and respiratory sync…
View article: Epidemiological Shifts in Respiratory Virus Infections Among Older Adults (≥65 Years) Before and After the COVID-19 Pandemic: An 18-Year Retrospective Study in the Republic of Korea
Epidemiological Shifts in Respiratory Virus Infections Among Older Adults (≥65 Years) Before and After the COVID-19 Pandemic: An 18-Year Retrospective Study in the Republic of Korea Open
We investigated respiratory virus epidemiology in older adults across pre-pandemic (2007–2019), pandemic (2020–2022), and post-pandemic (2023–2024) periods, focusing on how public health interventions shaped surveillance, prevalence, and s…
View article: Multivariate Assessment of Thyroid, Lipid, and Inflammatory Profiles by HBV Status and Viral Load: Age- and Sex-Specific Findings
Multivariate Assessment of Thyroid, Lipid, and Inflammatory Profiles by HBV Status and Viral Load: Age- and Sex-Specific Findings Open
Chronic hepatitis B virus (HBV) infection may influence extrahepatic systems, including endocrine and lipid regulation. In this cross-sectional study, 186 adults were stratified by HBV DNA status and viral load to examine thyroid function,…
View article: Enterovirus Detection Trends Based on Respiratory Specimens from a Single Tertiary Hospital in Korea (2018-2024): A Retrospective Study Using Multiplex PCR Data.
Enterovirus Detection Trends Based on Respiratory Specimens from a Single Tertiary Hospital in Korea (2018-2024): A Retrospective Study Using Multiplex PCR Data. Open
Enteroviruses (EVs) cause broad clinical manifestations, particularly in children. Certain serotypes have been implicated in respiratory infections; however, epidemiological studies analyzing EV circulation based on clinical respiratory sp…
View article: Retrospective Single-Center Study on the Epidemiological Characteristics of Influenza B Infections in Korea (2007–2024): Analysis of Sex, Age, and Seasonal Patterns
Retrospective Single-Center Study on the Epidemiological Characteristics of Influenza B Infections in Korea (2007–2024): Analysis of Sex, Age, and Seasonal Patterns Open
Influenza B, a globally prevalent respiratory virus, particularly affects children, the elderly, and individuals with chronic diseases. This retrospective single-center study analyzed long-term epidemiological trends using 23,284 PCR test …
View article: Long-Term Trends in Respiratory Syncytial Virus A Infections (2007–2024) in Korea
Long-Term Trends in Respiratory Syncytial Virus A Infections (2007–2024) in Korea Open
Background/Objectives: Respiratory syncytial virus A (RSV A) is the leading cause of respiratory infections, particularly in vulnerable populations. This study aimed to investigate the long-term epidemiological trends of RSV A infection in…
View article: The Prevalence of Multi-Type Infections Among Human Papillomavirus Types in Korean Women
The Prevalence of Multi-Type Infections Among Human Papillomavirus Types in Korean Women Open
The distribution of human papillomavirus (HPV) genotypes shows inconsistencies across countries, ethnicities, and socioeconomic levels. An in-depth identification of HPV infection rates and genotypes across regions, ethnicities, and age gr…
View article: Assessing inflammatory markers, C-reactive protein and neutrophil-to-lymphocyte ratio, in atrial fibrillation and normal sinus rhythm: A comparative analysis
Assessing inflammatory markers, C-reactive protein and neutrophil-to-lymphocyte ratio, in atrial fibrillation and normal sinus rhythm: A comparative analysis Open
View article: Comparison of Motor Nerve Conduction Findings in Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Charcot–Marie–Tooth Disease Type 1
Comparison of Motor Nerve Conduction Findings in Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Charcot–Marie–Tooth Disease Type 1 Open
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an acquired immune-mediated disorder characterized by weakness and sensory deficits. Charcot-Marie- Tooth type 1 (CMT1) is a slowly progressive hereditary degenerative dis…
View article: Retrospective Epidemiological Analysis of Influenza A Infections in a Single Hospital in Korea (2007–2024): Age, Sex, and Seasonal Patterns
Retrospective Epidemiological Analysis of Influenza A Infections in a Single Hospital in Korea (2007–2024): Age, Sex, and Seasonal Patterns Open
Influenza A is a respiratory virus that causes high infection rates and mortality worldwide, particularly affecting high-risk groups such as children, older adults, and individuals with chronic conditions. This retrospective study was cond…
View article: Trends in <i>Candida albicans</i> Bloodstream Infections and Antifungal Resistance in a Tertiary Care Hospital in South Korea (2013–2023)
Trends in <i>Candida albicans</i> Bloodstream Infections and Antifungal Resistance in a Tertiary Care Hospital in South Korea (2013–2023) Open
In this study, we aimed to analyze the annual, age- and sex-specific frequencies and antifungal resistance rates of Candida albicans infections over an 11-year period (2013 - 2023) at a university hospital in South Chungcheong Provi…
View article: Inflammatory Effects of Co-Exposure to Heavy Metals (Cd and Pb) and Respiratory Viruses (229E, OC43, and H3N2) on IL-6 and IL-8 Responses in U87 Glioblastoma Cells
Inflammatory Effects of Co-Exposure to Heavy Metals (Cd and Pb) and Respiratory Viruses (229E, OC43, and H3N2) on IL-6 and IL-8 Responses in U87 Glioblastoma Cells Open
Co-exposure to heavy metals and viruses can pose threats to cellular health by increasing cytotoxicity and inflammatory cytokine expression. We aimed to elucidate the interactions between these factors inhuman glioblastoma cells (U87). U87…
View article: Comparative Evaluation of Synergistic Antibacterial Effects in Blended Essential Oil against Gram-Positive and Gram-Negative Pathogens
Comparative Evaluation of Synergistic Antibacterial Effects in Blended Essential Oil against Gram-Positive and Gram-Negative Pathogens Open
The rising emergence of multidrug-resistant bacteria has heightened the search for novel antibiotic agents. Essential Oils (EOs) are complex combinations of volatile organic compounds generated by plants, with many exhibiting significant a…
View article: Refining Glaucoma Management: Korean Population-Specific Findings from Visual Field and Optical Coherence Tomography Testing
Refining Glaucoma Management: Korean Population-Specific Findings from Visual Field and Optical Coherence Tomography Testing Open
Background/Objectives: This study aimed to serve as a reference for establishing glaucoma evaluation standards for the Korean by analyzing the results of visual field tests and optical coherence tomography (OCT). We also determined the cor…
View article: Effects of irradiation on microbiological safety and physicochemical properties of dry pet food
Effects of irradiation on microbiological safety and physicochemical properties of dry pet food Open
View article: Analysis of Factors Affecting Blood Urea Nitrogen Levels and the Role of C-Reactive Protein in Elderly Patients Undergoing Dialysis
Analysis of Factors Affecting Blood Urea Nitrogen Levels and the Role of C-Reactive Protein in Elderly Patients Undergoing Dialysis Open
View article: Analysis of Inflammatory and Thyroid Hormone Levels Based on Hepatitis A and B Virus Immunity Status: Age and Sex Stratification
Analysis of Inflammatory and Thyroid Hormone Levels Based on Hepatitis A and B Virus Immunity Status: Age and Sex Stratification Open
This study investigated the potential associations between hepatitis virus antibody status and thyroid and inflammatory function. The C-reactive protein (CRP), thyroid-stimulating hormone (TSH), and free thyroxine (FT4) levels were measure…
View article: Prediction of the Cause of Glaucoma Disease Identified by Glaucoma Optical Coherence Tomography Test in Relation to Diabetes and Hypertension at a National Hospital in Seoul: A Retrospective Study
Prediction of the Cause of Glaucoma Disease Identified by Glaucoma Optical Coherence Tomography Test in Relation to Diabetes and Hypertension at a National Hospital in Seoul: A Retrospective Study Open
Glaucoma remains the primary cause of long-term blindness. While diabetes mellitus (DM) and hypertension (HTN) are known to influence glaucoma, other factors such as age and sex may be involved. In this retrospective study, we aimed to inv…
View article: Evaluation of Droplet Digital PCR for the Detection of <i>BRAF</i> V600E in Fine-Needle Aspiration Specimens of Thyroid Nodules
Evaluation of Droplet Digital PCR for the Detection of <i>BRAF</i> V600E in Fine-Needle Aspiration Specimens of Thyroid Nodules Open
We present a practical approach for optimizing ddPCR parameters that affect the separation of positive and negative droplets to reduce rain. Our approach to optimizing ddPCR parameters can be expanded to general ddPCR assays for specific m…
View article: Prevalence of <i>Chlamydia trachomatis</i> and <i>Neisseria gonorrhoeae</i> infections in Republic of Korea: Impacts of Sex, Age, and Testing Method
Prevalence of <i>Chlamydia trachomatis</i> and <i>Neisseria gonorrhoeae</i> infections in Republic of Korea: Impacts of Sex, Age, and Testing Method Open
The prevalence of Sexually Transmitted Diseases (STDs) is increasing globally, necessitating a quick and accurate diagnosis method for appropriate treatment selection. An analysis of venereal diseases conducted at U2Bio (Jangwon Medical Fo…
View article: Analysis of the Utility of MPT64, Drug Susceptibility Testing and Tuberculosis/Nontuberculous Mycobacteria Reverse Transcription Polymerase Chain Reaction for Tuberculosis Diagnosis and Efficiency Compared with Traditional Culture
Analysis of the Utility of MPT64, Drug Susceptibility Testing and Tuberculosis/Nontuberculous Mycobacteria Reverse Transcription Polymerase Chain Reaction for Tuberculosis Diagnosis and Efficiency Compared with Traditional Culture Open
Defining the molecular mechanisms underlying the dormant state of Mycobacterium tuberculosis (MTB) is essential for developing more effective treatments for tuberculosis (TB) infection. We investigated the positiv…
View article: Epidemiological Characterization of Respiratory Pathogens Using the Multiplex PCR FilmArray™ Respiratory Panel
Epidemiological Characterization of Respiratory Pathogens Using the Multiplex PCR FilmArray™ Respiratory Panel Open
Various pathogens can cause upper respiratory tract infections, presenting challenges in accurate diagnosis due to similar symptomatology. Therefore, rapid and precise diagnostic tests are crucial for effective treatment planning. Traditio…
View article: Characteristics of factor V and protein C based on results from Korean testing centers
Characteristics of factor V and protein C based on results from Korean testing centers Open
Objective The global incidence of thrombosis is increasing. However, research on thrombosis in the context of Korea is scarce. We aimed to analyze the relationship between factor V and protein C test results and thrombosis in Koreans throu…
View article: A Comparative Analysis of TSH Levels between Patients with Normal Sinus Rhythm and those with Atrial Fibrillation
A Comparative Analysis of TSH Levels between Patients with Normal Sinus Rhythm and those with Atrial Fibrillation Open
Atrial Fibrillation (AF) is the most prevalent persistent cardiac arrhythmia observed within the general population and is associated with increased morbidity and mortality. Despite the rising global prevalence of AF, the majority of exist…
View article: Prevalence of Diarrhea-Causing Pathogens in South Korea Analyzed Using Molecular Diagnostic Methods
Prevalence of Diarrhea-Causing Pathogens in South Korea Analyzed Using Molecular Diagnostic Methods Open
Gastrointestinal inflammation remains a prevalent global health concern. Prompt and accurate diagnosis of the condition is required to mitigate health risks in immunocompromised individuals and alleviate the economic burden linked to treat…
View article: Cytokine Expression During the Early Response of A549 Cells to Infection with Influenza Virus, <i>Alphacoronavirus</i> and <i>Betacoronavirus</i>
Cytokine Expression During the Early Response of A549 Cells to Infection with Influenza Virus, <i>Alphacoronavirus</i> and <i>Betacoronavirus</i> Open
The escalating incidence of coronavirus infections underscores the critical need for a comprehensive understanding of the differential impacts of Human Coronaviruses (HCoVs) belonging to the Alphacoronavirus and Betacoronaviru…
View article: Epidemiological Characterization of Respiratory Pathogens Using the Multiplex PCR FilmArray™ Respiratory Panel
Epidemiological Characterization of Respiratory Pathogens Using the Multiplex PCR FilmArray™ Respiratory Panel Open
Background : Different pathogens can cause upper respiratory tract infections. Since infections caused by different pathogens result in similar symptoms, it is challenging to identify the pathogen based on symptoms alone. Therefore, diagno…