Jai Smith
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Supplementary Figure 3 from Radiotherapy for Non–Small Cell Lung Cancer Induces DNA Damage Response in Both Irradiated and Out-of-field Normal Tissues Open
Changes in exosome concentration in individual patients (particles per mL) over course of treatment.
Data from Radiotherapy for Non–Small Cell Lung Cancer Induces DNA Damage Response in Both Irradiated and Out-of-field Normal Tissues Open
Purpose: To study the response of irradiated and out-of-field normal tissues during localized curative intent radiotherapy.Experimental Design: Sixteen patients with non–small cell lung carcinoma (NSCLC) received 60 Gy in 30 fractions of d…
Supplementary Figure 3 from Radiotherapy for Non–Small Cell Lung Cancer Induces DNA Damage Response in Both Irradiated and Out-of-field Normal Tissues Open
Changes in exosome concentration in individual patients (particles per mL) over course of treatment.
Supplementary Figure 2 from Radiotherapy for Non–Small Cell Lung Cancer Induces DNA Damage Response in Both Irradiated and Out-of-field Normal Tissues Open
Mean (+/- SD) Changes in concentration of plasma cytokine levels at baseline, 1-hour, 24-hours and 4-weeks after commencement of RT stratified by use of concurrent chemotherapy. Change at 1-hour in MDC and 4 weeks in MIP-1α is marked with …
Supplementary Figure 2 from Radiotherapy for Non–Small Cell Lung Cancer Induces DNA Damage Response in Both Irradiated and Out-of-field Normal Tissues Open
Mean (+/- SD) Changes in concentration of plasma cytokine levels at baseline, 1-hour, 24-hours and 4-weeks after commencement of RT stratified by use of concurrent chemotherapy. Change at 1-hour in MDC and 4 weeks in MIP-1α is marked with …
Supplementary Figure 1 from Radiotherapy for Non–Small Cell Lung Cancer Induces DNA Damage Response in Both Irradiated and Out-of-field Normal Tissues Open
Association between PTV volume and excess (above the baseline) average number of foci per cell (a) and excess proportion of cells with {greater than or equal to} 6 γ-H2AX foci (b) at 1-hour and 24-hours.
Data from Radiotherapy for Non–Small Cell Lung Cancer Induces DNA Damage Response in Both Irradiated and Out-of-field Normal Tissues Open
Purpose: To study the response of irradiated and out-of-field normal tissues during localized curative intent radiotherapy.Experimental Design: Sixteen patients with non–small cell lung carcinoma (NSCLC) received 60 Gy in 30 fractions of d…
Supplementary Figure 1 from Radiotherapy for Non–Small Cell Lung Cancer Induces DNA Damage Response in Both Irradiated and Out-of-field Normal Tissues Open
Association between PTV volume and excess (above the baseline) average number of foci per cell (a) and excess proportion of cells with {greater than or equal to} 6 γ-H2AX foci (b) at 1-hour and 24-hours.
Self-reported beta-lactam allergy: inpatients in government funded and privately funded hospitals Cape Town, South Africa Open
Background Up to a quarter of inpatients in high-income countries self-report beta-lactam allergy (BLA), which if incorrect, can increase use of alternative antibiotics that impact on bacterial resistance.. The epidemiology of BLA in low- …
Longitudinal Monitoring of Intra-Tumoural Heterogeneity Using Optical Barcoding of Patient-Derived Colorectal Tumour Models Open
Geno- and phenotypic heterogeneity amongst cancer cell subpopulations are established drivers of treatment resistance and tumour recurrence. However, due to the technical difficulty associated with studying such intra-tumoural heterogeneit…
CD44v6 Defines a New Population of Circulating Tumor Cells Not Expressing EpCAM Open
Circulating tumor cells (CTCs) are promising diagnostic and prognostic tools for clinical use. In several cancers, including colorectal and breast, the CTC load has been associated with a therapeutic response as well as progression-free an…
Targeting of TP53-independent cell cycle checkpoints overcomes FOLFOX resistance in Metastatic Colorectal Cancer Open
Patients with colorectal cancer (CRC) frequently develop liver metastases during the course of their disease. A substantial proportion of them receive neoadjuvant FOLFOX (5-Fluorouracil, Oxaliplatin, Leucovorin) prior to surgery in an atte…
Radiotherapy for Non–Small Cell Lung Cancer Induces DNA Damage Response in Both Irradiated and Out-of-field Normal Tissues Open
Purpose: To study the response of irradiated and out-of-field normal tissues during localized curative intent radiotherapy. Experimental Design: Sixteen patients with non–small cell lung carcinoma (NSCLC) received 60 Gy in 30 fractions of …