Jake Mandziuk
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View article: Pneumatoceles or Not? Case Reports on Pulmonary Cystic Lesions in Infants
Pneumatoceles or Not? Case Reports on Pulmonary Cystic Lesions in Infants Open
Pulmonary cystic lesions in infants are uncommon and can present diagnostic challenges due to overlapping radiologic features with other cystic lung conditions. We present 2 cases of left lung cystic lesions in infants. Initial high-resolu…
View article: Progressive Dyspnea With Recurrent Pneumothoraces
Progressive Dyspnea With Recurrent Pneumothoraces Open
View article: Radiologic-Pathologic Correlation of Liver Tumors
Radiologic-Pathologic Correlation of Liver Tumors Open
Radiologic and pathologic features of common and/or critical tumor or tumor-like diagnoses (lesions) of the liver are discussed within. Hepatocellular lesions (focal nodular hyperplasia, hepatocellular adenoma, hepatocellular carcinoma, an…
View article: High Throughput Assay Identifies Glafenine as a Corrector for the Folding Defect in Corneal Dystrophy–Causing Mutants of SLC4A11
High Throughput Assay Identifies Glafenine as a Corrector for the Folding Defect in Corneal Dystrophy–Causing Mutants of SLC4A11 Open
These data suggest that glafenine, and perhaps other NSAIDs, hold potential as therapeutics for misfolded membrane proteins, like SLC4A11. The high throughput approach described here can be modified to identify correctors of other misfolde…