Jakub Hadzik
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View article: Polyphenol Composition of Traditional Decoctions from Polygoni Cuspidati Rhizoma et Radix of Different Origin and Their Impact on Human Gingival Fibroblasts
Polyphenol Composition of Traditional Decoctions from Polygoni Cuspidati Rhizoma et Radix of Different Origin and Their Impact on Human Gingival Fibroblasts Open
Polygoni cuspidati rhizoma et radix (rhizomes of Reynoutria japonica Houtt.) have a long tradition of use in traditional Chinese medicine confirmed by numerous contemporary studies. Our earlier results implied the potential use of decoctio…
View article: Ionic Doping of Hydroxyapatite for Bone Regeneration: Advances in Structure and Properties over Two Decades—A Narrative Review
Ionic Doping of Hydroxyapatite for Bone Regeneration: Advances in Structure and Properties over Two Decades—A Narrative Review Open
Autogenous grafts remain the “gold standard” in bone tissue grafting procedures; however, limitations such as donor site morbidity, invasiveness, and limited availability have spurred research into alternative materials. Hydroxyapatite (HA…
View article: Comparative Analysis of Heavy Metal Content in Impacted Third Molars from Industrial and Non-Industrial Areas and Its Effect on the Isolation, Culture, and Proliferation of Dental Stem Cells (DSCs)
Comparative Analysis of Heavy Metal Content in Impacted Third Molars from Industrial and Non-Industrial Areas and Its Effect on the Isolation, Culture, and Proliferation of Dental Stem Cells (DSCs) Open
Background: This study investigates the impact of environmental pollution on the quality and viability of dental stem cells (DSCs) from impacted third molars. By comparing DSCs from patients in industrial areas with high air pollution and …
View article: Zirconia Dental Implant Designs and Surface Modifications: A Narrative Review
Zirconia Dental Implant Designs and Surface Modifications: A Narrative Review Open
Titanium currently has a well-established position as the gold standard for manufacturing dental implants; however, it is not free of flaws. Mentions of possible soft-tissue discoloration, corrosion, and possible allergic reactions have le…
View article: Allogenic Bone Graft in Dentistry: A Review of Current Trends and Developments
Allogenic Bone Graft in Dentistry: A Review of Current Trends and Developments Open
In an effort to prepare non-autologous bone graft or biomaterial that would possess characteristics comparable to autologous bone, many different allogenic bone derivatives have been created. Although different existing processing methods …
View article: An Experimental Anodized and Low-Pressure Oxygen Plasma-Treated Titanium Dental Implant Surface—Preliminary Report
An Experimental Anodized and Low-Pressure Oxygen Plasma-Treated Titanium Dental Implant Surface—Preliminary Report Open
Chemical composition and physical parameters of the implant surface, such as roughness, regulate the cellular response leading to implant bone osseointegration. Possible implant surface modifications include anodization or the plasma elect…
View article: Oral Wound Healing Potential of Polygoni Cuspidati Rhizoma et Radix Decoction—In Vitro Study
Oral Wound Healing Potential of Polygoni Cuspidati Rhizoma et Radix Decoction—In Vitro Study Open
Polygoni Cuspidati Rhizoma et Radix (syn. rhizomes of Reynoutria japonica Houtt.) is a pharmacopoeial raw material in Europe and China. In traditional medicine, one of the applications for Reynoutria japonica rhizomes is wound healing. In …
View article: Effect of the Lateral Bone Augmentation Procedure in Correcting Peri-Implant Bone Dehiscence Defects: A 7-Years Retrospective Study
Effect of the Lateral Bone Augmentation Procedure in Correcting Peri-Implant Bone Dehiscence Defects: A 7-Years Retrospective Study Open
Guided bone regeneration (GBR) is a well-documented and widely-used dental surgical procedure for the treatment of various types of alveolar bone defects. The aim of the study was to evaluate the long-term effectiveness of the GBR procedur…
View article: Bone tissue 3D bioprinting in regenerative dentistry through the perspective of the diamond concept of healing: A narrative review
Bone tissue 3D bioprinting in regenerative dentistry through the perspective of the diamond concept of healing: A narrative review Open
Three-dimensional bioprinting technology appears to be a promising solution for the treatment and reconstruction of a wide range of maxillofacial bone defects. In this review, the authors discuss different bioprinting solutions and options…
View article: Soft-Tissue Augmentation around Dental Implants with a Connective Tissue Graft (CTG) and Xenogeneic Collagen Matrix (CMX)—5-Year Follow-Up
Soft-Tissue Augmentation around Dental Implants with a Connective Tissue Graft (CTG) and Xenogeneic Collagen Matrix (CMX)—5-Year Follow-Up Open
Proper horizontal and vertical thickness of the gingival connective tissue has been proven to be one of the success criteria in dental implant and reconstructive surgery. When thin tissue is found, gingiva augmentation methods can be used …
View article: An Experimental Anodized Titanium Surface for Transgingival Dental Implant Elements—Preliminary Report
An Experimental Anodized Titanium Surface for Transgingival Dental Implant Elements—Preliminary Report Open
The characteristics such as microtopography, physical and chemical properties influence the behavior of an implant in a soft tissue. Anodization—as a potent method of titanium alloy surface modification—of the transgingival abutment or hea…
View article: The Appliance of A-PRF and CGF in the Treatment of Impacted Mandibular Third Molar Extraction Sockets—Narrative Review
The Appliance of A-PRF and CGF in the Treatment of Impacted Mandibular Third Molar Extraction Sockets—Narrative Review Open
Tooth extractions, especially of impacted lower third molars, are among the most common procedures performed in dental practices. The continuity of the patient’s oral mucosa, which is interrupted during them, can manifest itself in general…
View article: Role of implant loading time in the prevention of marginal bone loss after implant-supported restorations: A targeted review
Role of implant loading time in the prevention of marginal bone loss after implant-supported restorations: A targeted review Open
The implant-supported restoration of missing teeth is a recognized method of treatment that ensures a functional, esthetic and durable effect, along with patient satisfaction. However, the preferable time of dental implant loading is under…
View article: Fractal Dimension and Texture Analysis in the Assessment of Experimental Laser-Induced Periodic Surface Structures (LIPSS) Dental Implant Surface—In Vitro Study Preliminary Report
Fractal Dimension and Texture Analysis in the Assessment of Experimental Laser-Induced Periodic Surface Structures (LIPSS) Dental Implant Surface—In Vitro Study Preliminary Report Open
Laser-induced periodic surface structures (LIPSS) are the sub-wavelength periodic nanostructures generated by the femtosecond laser. Implant topography and its nanostructural changes can be important for biomedical applications. In order t…
View article: Aesthetic Outcomes of Early Occlusal Loaded SLA Dental Implants with Hydroxyl Ion Modified Surface—A 12 Months Prospective Study
Aesthetic Outcomes of Early Occlusal Loaded SLA Dental Implants with Hydroxyl Ion Modified Surface—A 12 Months Prospective Study Open
Background: Many efforts have been made recently to arrange a newer, more hydrophilic and more osteoconductive implant surface. One of the possible options in this matter is modification with hydroxyl ion. Materials and Methods: Forty impl…
View article: Reynoutria Rhizomes as a Natural Source of SARS-CoV-2 Mpro Inhibitors–Molecular Docking and In Vitro Study
Reynoutria Rhizomes as a Natural Source of SARS-CoV-2 Mpro Inhibitors–Molecular Docking and In Vitro Study Open
More than a year has passed since the world began to fight the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the Coronavirus disease 2019 (COVID-19) pandemic, and still it spreads around the world, muta…
View article: Monitoring of Changes in Masticatory Muscle Stiffness after Gum Chewing Using Shear Wave Elastography
Monitoring of Changes in Masticatory Muscle Stiffness after Gum Chewing Using Shear Wave Elastography Open
This study aimed to investigate if intensive exercise affects the stiffness of the masticatory muscles measured with shear-wave elastography. The study included a cohort of healthy adults (n = 40) aged 40 ± 11 years. In each individual, th…
View article: Dentists can provide reliable shear wave elastography measurements of the stiffness of masseter muscles: A possible scenario for a faster diagnostic process
Dentists can provide reliable shear wave elastography measurements of the stiffness of masseter muscles: A possible scenario for a faster diagnostic process Open
The diagnostic accuracy of measuring masseter muscle stiffness was acceptable among dentists after the training. For this reason, the patient can be diagnosed by a single TMD specialist. This can shorten the diagnostic process and reduce t…
View article: Phenolic Compounds of Reynoutria sp. as Modulators of Oral Cavity Lactoperoxidase System
Phenolic Compounds of Reynoutria sp. as Modulators of Oral Cavity Lactoperoxidase System Open
Lactoperoxidase (LPO) together with its (pseudo)halogenation cycle substrates, H2O2 and thiocyanate ions oxidized to hypothiocyanite ions, form one of the main systems involved in antimicrobial defense within the oral cavity. In bacterial …
View article: Early Loading of Titanium Dental Implants with Hydroxyl Ion Modified Surface: A 12-Month Prospective Clinical Trial
Early Loading of Titanium Dental Implants with Hydroxyl Ion Modified Surface: A 12-Month Prospective Clinical Trial Open
(1) Background: implant surface topology and active hydrophilic ions could have some benefit on implant osteointegration and stability; (2) methods: 40 adult patients, suffering from a single missing tooth in the aesthetic zone, were enrol…
View article: Short (6 mm) and Regular Dental Implants in the Posterior Maxilla–7-Years Follow-up Study
Short (6 mm) and Regular Dental Implants in the Posterior Maxilla–7-Years Follow-up Study Open
Short 6 mm dental implants are considered as an alternative to the maxillary sinus elevation and bone augmentation procedure where there is a reduced alveolar ridge height. The aim of this study was to compare the implant survival rate bet…
View article: Proanthocyanidins and Flavan-3-ols in the Prevention and Treatment of Periodontitis—Immunomodulatory Effects, Animal and Clinical Studies
Proanthocyanidins and Flavan-3-ols in the Prevention and Treatment of Periodontitis—Immunomodulatory Effects, Animal and Clinical Studies Open
This paper continues the systematic review on proanthocyanidins and flavan-3-ols in the prevention and treatment of periodontal disease and covers the immunomodulatory effects, and animal- and clinical studies, while the other part discuss…
View article: Proanthocyanidins and Flavan-3-Ols in the Prevention and Treatment of Periodontitis—Antibacterial Effects
Proanthocyanidins and Flavan-3-Ols in the Prevention and Treatment of Periodontitis—Antibacterial Effects Open
Flavan-3-ols and their oligomeric forms called proanthocyanidins are polyphenolic compounds occurring in several foodstuffs and in many medicinal herbs. Their consumption is associated with numerous health benefits. They exhibit antioxidan…
View article: Proanthocyanidins and Flavan-3-ols in the Prevention and Treatment of Periodontitis - Immunomodulatory Effects, Animal and Clinical Studies
Proanthocyanidins and Flavan-3-ols in the Prevention and Treatment of Periodontitis - Immunomodulatory Effects, Animal and Clinical Studies Open
This paper continues the review study on antimicrobial properties relevant to the periodontal diseases. Inflammation as a major response of the periodontal tissues attacked by pathogenic microbes can significantly exacerbate the condition.…
View article: Proanthocyanidins and Flavan-3-ols in the Prevention and Treatment of Periodontitis - Antibacterial Effects.
Proanthocyanidins and Flavan-3-ols in the Prevention and Treatment of Periodontitis - Antibacterial Effects. Open
Flavan-3-ols and their oligomeric forms called proanthocyanidins are polyphenolic compounds occurring in several foodstuffs and in many medicinal herbs. Their consumption is associated with numerous health benefits. Their bioactivities inc…
View article: Cytotoxic Effect of Vanicosides A and B from Reynoutria sachalinensis against Melanotic and Amelanotic Melanoma Cell Lines and in silico Evaluation for Inhibition of BRAFV600E and MEK1
Cytotoxic Effect of Vanicosides A and B from Reynoutria sachalinensis against Melanotic and Amelanotic Melanoma Cell Lines and in silico Evaluation for Inhibition of BRAFV600E and MEK1 Open
Vanicosides A and B are the esters of hydroxycinnamic acids with sucrose, occurring in a few plant species from the Polygonaceae family. So far, vanicosides A and B have not been evaluated for anticancer activity against human malignant me…
View article: Evaluation of the three methods of bacterial decontamination on implants with three different surfaces
Evaluation of the three methods of bacterial decontamination on implants with three different surfaces Open
In the following paper, the superiority of combined chemical-mechanical method of decontaminating the surface of the implant on SLA and machined-surface implants was proved. On the contrary, Er:YAG laser irradiation was reported as the bes…
View article: Antimicrobial Efficacy of Different Decontamination Methods as Tested on Dental Implants with Various Types of Surfaces
Antimicrobial Efficacy of Different Decontamination Methods as Tested on Dental Implants with Various Types of Surfaces Open
BACKGROUND Peri-implantitis is an inflammatory reaction affecting both hard and soft tissues surrounding dental implants. This pathological condition is caused by a polymicrobial aggressive biofilm that colonizes the implant and abutment s…
View article: COVID-19 and professional dental practice. The Polish Dental Association Working Group recommendations for procedures in dental office during an increased epidemiological risk
COVID-19 and professional dental practice. The Polish Dental Association Working Group recommendations for procedures in dental office during an increased epidemiological risk Open
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Dominiak M, Różyło-Kalinowska I, Gedrange T, et al. COVID-19 and professional dental practice. The Polish Dental Association Working Group recommendations fo…
View article: Child’s dental age as a biological marker of individual development
Child’s dental age as a biological marker of individual development Open
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Makeev V, Isakova O, Shybinskyy V, Hadzik J, Krupnyk A. Child’s dental age as a biological marker of individual development. Journal of Stomatology. 2020;73(…