Jakub Honěk
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View article: Eicosanoids in Coronary Sinus Correlate with NT-proBNP in Heart Failure with Reduced Ejection Fraction Indicated to Resynchronization Therapy: Insights from Eicosanoids in Human Heart Failure Study
Eicosanoids in Coronary Sinus Correlate with NT-proBNP in Heart Failure with Reduced Ejection Fraction Indicated to Resynchronization Therapy: Insights from Eicosanoids in Human Heart Failure Study Open
Introduction The diagnostic potential of eicosanoids, metabolites of arachidonic acid with cardio-renal activity, in chronic heart failure with reduced ejection fraction (HFrEF) remains unclear. The aim was to investigate levels of eicosan…
View article: Endovenous laser ablation of saphenous veins – favorable clinical results confirmtheoretical advantages of the 1940nm diode laser
Endovenous laser ablation of saphenous veins – favorable clinical results confirmtheoretical advantages of the 1940nm diode laser Open
Introduction: Endovenous laser ablation (EVLA) is a recognized alternative to surgical treatment of varicose veins, although an optimal laser generator and its settings still remain a matter of debate. The aim of our study was to correlate…
View article: Left ventricular reverse remodelling and its predictors in non‐ischaemic cardiomyopathy
Left ventricular reverse remodelling and its predictors in non‐ischaemic cardiomyopathy Open
Adverse remodelling following an initial insult is the hallmark of heart failure (HF) development and progression. It is manifested as changes in size, shape, and function of the myocardium. While cardiac remodelling may be compensatory in…
View article: Endovenous laser ablation of saphenous vein – mid-term results confirm permanent closure and possibility to treat more lesions in one procedure
Endovenous laser ablation of saphenous vein – mid-term results confirm permanent closure and possibility to treat more lesions in one procedure Open
Introduction: Endovenous Laser Ablation (EVLA) is a common alternative to surgical treatment of varicose veins. The aim of our study was to demonstrate that laser occlusion is durable, that we can treat all patients in a one day setting, e…
View article: Carotid artery plaque composition and distribution: near-infrared spectroscopy and intravascular ultrasound analysis
Carotid artery plaque composition and distribution: near-infrared spectroscopy and intravascular ultrasound analysis Open
Most atherosclerotic plaques (APs) form in typical predilection areas of low endothelial shear stress (ESS). On the contrary, previous data hinted that plaques rupture in their proximal parts where accelerated blood flow causes high ESS. I…
View article: Nonpharmacological Treatment of Atrial Fibrillation: What Is the Role of Device Therapy?
Nonpharmacological Treatment of Atrial Fibrillation: What Is the Role of Device Therapy? Open
Atrial fibrillation is the most common arrhythmia in the adult population, and its incidence and prevalence are still rising. Cardiac devices are widely used in clinical practice in the management of various rhythm disturbances and heart f…
View article: MicroRNA-331 and microRNA-151-3p as biomarkers in patients with ST-segment elevation myocardial infarction
MicroRNA-331 and microRNA-151-3p as biomarkers in patients with ST-segment elevation myocardial infarction Open
We sought to analyse plasma levels of peripheral blood microRNAs (miRs) as biomarkers of ST-segment-elevation myocardial infarction (STEMI) due to type-1 myocardial infarction as a model situation of vulnerable plaque (VP) rupture. Samples…
View article: High-grade patent foramen ovale is a risk factor of unprovoked decompression sickness in recreational divers
High-grade patent foramen ovale is a risk factor of unprovoked decompression sickness in recreational divers Open
View article: Catheter-based endovenous laser ablation of saphenous veins in the treatment of symptomatic venous reflux: Early results
Catheter-based endovenous laser ablation of saphenous veins in the treatment of symptomatic venous reflux: Early results Open
Úvod: Katetrizační endovenózní laserová ablace (EVLA) je běžně užívaná alternativa chirurgické léčby varixů dolních končetin a postupně se stává metodou volby. V této observační studii jsme si kladli za cíl prokázat, zda je tato metoda bez…
View article: History and current use of mild therapeutic hypothermia after cardiac arrest
History and current use of mild therapeutic hypothermia after cardiac arrest Open
In spite of many years of development and implementation of pre-hospital advanced life support programmes, the survival rate of out-of-hospital cardiac arrest (OHCA) used to be very poor. Neurologic injury from cerebral hypoxia is the most…
View article: The role of near-infrared spectroscopy in the detection of vulnerable atherosclerotic plaques
The role of near-infrared spectroscopy in the detection of vulnerable atherosclerotic plaques Open
Coronary artery disease is the leading cause of mortality worldwide. Most acute coronary syndromes are caused by a rupture of a vulnerable atherosclerotic plaque which can be characterized by a lipid-rich necrotic core with an overlying th…
View article: First-in-man near-infrared spectroscopy proof of lipid-core embolization during carotid artery stenting
First-in-man near-infrared spectroscopy proof of lipid-core embolization during carotid artery stenting Open
Intravascular near-infrared spectroscopy (NIRS), which has been used in over 5,000 patients to identify the lipid-core plaques (LCP) that cause coronary events, may also assist in the characterization of the carotid atherosclerotic lesions…
View article: Intravascular Near-Infrared Spectroscopy: A Possible Tool for Optimizing the Management of Carotid Artery Disease
Intravascular Near-Infrared Spectroscopy: A Possible Tool for Optimizing the Management of Carotid Artery Disease Open
Stroke is the second most common cause of morbidity and mortality in the Western nations. It is estimated that approximately one-fifth of all strokes or transient ischemic attacks are caused by carotid artery disease. Thus, treatment of ca…