Jakub Mrázek
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View article: Impact of Sex, Gonadectomy, and Repeated Restraint Stress on Gut Microbiome in Mice
Impact of Sex, Gonadectomy, and Repeated Restraint Stress on Gut Microbiome in Mice Open
Recently, the bidirectional connection between the gastrointestinal microbiota and the brain has gained interest in many research studies. Findings have highlighted the potential role of stress and sex hormones in modulating the gut microb…
View article: The Inclusion of <i>Hermetia Illucens</i> Larvae Meal in the Diet of Laying Hens (Hy‐Line Brown) Affects the Caecal Bacterial Composition and Diversity
The Inclusion of <i>Hermetia Illucens</i> Larvae Meal in the Diet of Laying Hens (Hy‐Line Brown) Affects the Caecal Bacterial Composition and Diversity Open
Background The poultry industry is increasingly looking for sustainable feed ingredients which support animal productivity. Insects, such as the larvae of Hermetia illucens , represent a promising alternative protein source that has a posi…
View article: Exploring the associations between preen oil bacterial, chemical and proteomic profiles of passerines
Exploring the associations between preen oil bacterial, chemical and proteomic profiles of passerines Open
View article: Dietary inclusion of Hermetia illucens larvae meal modifies caecal microbiota diversity and composition in barbary partridges (Alectoris barbara)
Dietary inclusion of Hermetia illucens larvae meal modifies caecal microbiota diversity and composition in barbary partridges (Alectoris barbara) Open
In the present study, we examined the influence of the dietary inclusion of black soldier fly (BSF) larvae meal on the diversity and composition of the bacterial community in the caecum of Barbary partridges (Alectoris barbara). A total of…
View article: The effect of the administration form of antibiotic therapy on the gut microbiome in patients with infected diabetic foot ulcers - DFIATIM trial
The effect of the administration form of antibiotic therapy on the gut microbiome in patients with infected diabetic foot ulcers - DFIATIM trial Open
Background Diabetic foot infections (DFIs) contribute to the global disability burden. Beta-lactams are the most commonly used antibiotics for treating DFIs. However, the use of antibiotics may lead to disruption of the healthy balance of …
View article: The inclusion of insect meal from Hermetia illucens larvae in the diet of laying hens (Hy-line Brown) affects the caecal diversity of methanogenic archaea
The inclusion of insect meal from Hermetia illucens larvae in the diet of laying hens (Hy-line Brown) affects the caecal diversity of methanogenic archaea Open
View article: Diabetes and gut microbiome
Diabetes and gut microbiome Open
Diabetes mellitus represents a significant global health problem. The number of people suffering from this metabolic disease is constantly rising and although the incidence is heterogeneous depending on region, country, economic situation,…
View article: Inclusion of Tenebrio molitor larvae meal in the diet of barbary partridge (Alectoris barbara) improves caecal bacterial diversity and composition
Inclusion of Tenebrio molitor larvae meal in the diet of barbary partridge (Alectoris barbara) improves caecal bacterial diversity and composition Open
View article: Long Terminal Repeats of Gammaretroviruses Retain Stable Expression after Integration Retargeting
Long Terminal Repeats of Gammaretroviruses Retain Stable Expression after Integration Retargeting Open
Retroviruses integrate into the genomes of infected host cells to form proviruses, a genetic platform for stable viral gene expression. Epigenetic silencing can, however, hamper proviral transcriptional activity. As gammaretroviruses (γRVs…
View article: Comparison of three primer pairs for molecular sex determination in Eurasian pygmy owls (Glaucidium passerinum)
Comparison of three primer pairs for molecular sex determination in Eurasian pygmy owls (Glaucidium passerinum) Open
View article: Defined Pig Microbiota Mixture as Promising Strategy against Salmonellosis in Gnotobiotic Piglets
Defined Pig Microbiota Mixture as Promising Strategy against Salmonellosis in Gnotobiotic Piglets Open
Probiotics are a potential strategy for salmonellosis control. A defined pig microbiota (DPM) mixture of nine bacterial strains previously exhibited probiotic and anti-Salmonella properties in vitro. Therefore, we evaluated its gut coloniz…
View article: Long Terminal Repeats of Gammaretroviruses Retain Stable Expression After Integration Retargeting or Knock-In into the Restrictive Chromatin of Lamina-Associated Domains
Long Terminal Repeats of Gammaretroviruses Retain Stable Expression After Integration Retargeting or Knock-In into the Restrictive Chromatin of Lamina-Associated Domains Open
Retroviruses integrate their genomes into the genomes of infected host cells and form a genetic platform for stable gene expression. Epigenetic silencing can, however, hamper the expression of integrated provirus. As gammaretroviruses (γRV…
View article: Does PAD and microcirculation status impact the tissue availability of intravenously administered antibiotics in patients with infected diabetic foot? Results of the DFIATIM substudy
Does PAD and microcirculation status impact the tissue availability of intravenously administered antibiotics in patients with infected diabetic foot? Results of the DFIATIM substudy Open
Aims/hypothesis The aim of this substudy (Eudra CT No:2019-001997-27)was to assess ATB availability in patients with infected diabetic foot ulcers(IDFUs)in the context of microcirculation and macrocirculation status. Methods For this subst…
View article: Microbiome composition and presence of cultivable commensal groups of Southern Tamanduas (Tamandua tetradactyla) varies with captive conditions
Microbiome composition and presence of cultivable commensal groups of Southern Tamanduas (Tamandua tetradactyla) varies with captive conditions Open
View article: OrthoRefine: automated enhancement of prior ortholog identification via synteny
OrthoRefine: automated enhancement of prior ortholog identification via synteny Open
Background Identifying orthologs continues to be an early and imperative step in genome analysis but remains a challenging problem. While synteny (conservation of gene order) has previously been used independently and in combination with o…
View article: Effects of Leishmania major infection on the gut microbiome of resistant and susceptible mice
Effects of Leishmania major infection on the gut microbiome of resistant and susceptible mice Open
View article: Thiothrix and Sulfurovum genera dominate bacterial mats in Slovak cold sulfur springs
Thiothrix and Sulfurovum genera dominate bacterial mats in Slovak cold sulfur springs Open
Microbiota of sulfur-rich environments has been extensively studied due to the biotechnological potential of sulfur bacteria, or as a model of ancient life. Cold terrestrial sulfur springs are less studied compared to sulfur-oxidizing micr…
View article: The effect of different levels of Hermetia illucens oil inclusion on caecal microbiota of Japanese quails (Coturnix japonica, Gould, 1837)
The effect of different levels of Hermetia illucens oil inclusion on caecal microbiota of Japanese quails (Coturnix japonica, Gould, 1837) Open
In this study, we investigated the effect of the dietary inclusion of Hermetia illucens larvae oil on the diversity and structure of the bacterial community of the caecal content of Japanese quails ( Coturnix japonica ). A total of 40 quai…
View article: Profiling of adrenal corticosteroids in blood and local tissues of mice during chronic stress
Profiling of adrenal corticosteroids in blood and local tissues of mice during chronic stress Open
Stress increases plasma concentrations of corticosteroids, however, their tissue levels are unclear. Using a repeated social defeat paradigm, we examined the impact of chronic stress on tissue levels of corticosterone (CORT), progesterone …
View article: The influence of antibiotic treatment on the behavior and gut microbiome of adult rats neonatally insulted with lipopolysaccharide
The influence of antibiotic treatment on the behavior and gut microbiome of adult rats neonatally insulted with lipopolysaccharide Open
View article: Antibiotic-induced dysbiosis does not potentiate the effect of lipopolysaccharide insult in male Wistar rats
Antibiotic-induced dysbiosis does not potentiate the effect of lipopolysaccharide insult in male Wistar rats Open
The present study investigated whether neonatal exposure to the proinflammatory endotoxin lipopolysaccharide (LPS) followed by antibiotic (ATB)-induced dysbiosis in early adulthood could induce schizophrenia-like behavioral changes in adul…
View article: Metabolic profiling of silymarin constituents in urine and feces of healthy volunteers: A 90-day study
Metabolic profiling of silymarin constituents in urine and feces of healthy volunteers: A 90-day study Open
This study examined the metabolism of flavonolignans and taxifolin in 33 healthy adult male volunteers, who received 200 mg of silymarin orally twice daily for three months. First-morning urine and feces collected on days 10 and 90 were an…
View article: Host Species Affects Bacterial Evenness, but Not Diversity: Comparison of Fecal Bacteria of Cows and Goats Offered the Same Diet
Host Species Affects Bacterial Evenness, but Not Diversity: Comparison of Fecal Bacteria of Cows and Goats Offered the Same Diet Open
The aim of this study was to compare the diversity and composition of fecal bacteria in goats and cows offered the same diet and to evaluate the influence of animal species on the gut microbiome. A total of 17 female goats (Blond Adamellan…
View article: Dysbiosis of skin microbiome and gut microbiome in melanoma progression
Dysbiosis of skin microbiome and gut microbiome in melanoma progression Open
View article: Additional file 22 of Dysbiosis of skin microbiome and gut microbiome in melanoma progression
Additional file 22 of Dysbiosis of skin microbiome and gut microbiome in melanoma progression Open
Additional file 22. Pairwise comparison ofalpha diversity of cutaneous bacterial communities of animal models (white,crossbred, MeLiM piglets) in different skin samples (healthy skin, melanoma surfaceand melanoma tissue), at different stat…
View article: Additional file 27 of Dysbiosis of skin microbiome and gut microbiome in melanoma progression
Additional file 27 of Dysbiosis of skin microbiome and gut microbiome in melanoma progression Open
Additional file 27. Predicted functional KEGGpathways at levels 1, 2 and 3 in the faecal microbiota of different animalmodels (white, crossbred, MeLiM piglets) at different disease stat (control,melanoma regression and melanoma regression)
View article: Additional file 24 of Dysbiosis of skin microbiome and gut microbiome in melanoma progression
Additional file 24 of Dysbiosis of skin microbiome and gut microbiome in melanoma progression Open
Additional file 24. The relative abundances ofthe bacterial community in skin microbiota of several cutaneous samples fromdifferent animal models at different ages at phylum and genus levels.
View article: Additional file 26 of Dysbiosis of skin microbiome and gut microbiome in melanoma progression
Additional file 26 of Dysbiosis of skin microbiome and gut microbiome in melanoma progression Open
Additional file 26. Predicted functional KEGGpathways at levels 1, 2 and 3 in the skin microbiome of several cutaneoussamples (healthy skin, melanoma surface and melanoma tissue) from differentanimal models (white, crossbred, MeLiM piglets…
View article: Additional file 25 of Dysbiosis of skin microbiome and gut microbiome in melanoma progression
Additional file 25 of Dysbiosis of skin microbiome and gut microbiome in melanoma progression Open
Additional file 25. The relative abundances ofthe bacterial community in the faecal microbiota of different animal models atdifferent ages at phylum and genus levels.
View article: Additional file 23 of Dysbiosis of skin microbiome and gut microbiome in melanoma progression
Additional file 23 of Dysbiosis of skin microbiome and gut microbiome in melanoma progression Open
Additional file 23. Pairwise comparison ofalpha diversity of faecal microbiota of animal models (white, crossbred, MeLiMpiglets) at different stat (control, melanoma regression and melanomaregression) at different ages (8, 10, 12 weeks) me…