Explanipedia

The evolving literature on the ethics of artificial intelligence for healthcare: a PRISMA scoping review Open

Yufei Wang, Heather Wurtz, Lillian Morgado, Catherine E. A. Scipion, Kim Williams , et al. · 2025

This scoping review analyzes the literature on the ethics of artificial intelligence (AI) tools in healthcare to identify trends across populations and shifts in published research between 2020 and 2024. We conducted a PRISMA scoping revie…

Medicaid expansion and diagnosis experiences of people with frontotemporal dementia Open

Catherine E. A. Scipion, Karen E. Nielsen, Heather M. Wurtz, Jalayne J. Arias · 2025

INTRODUCTION Timely and accurate diagnosis of frontotemporal dementia (FTD) is essential for improving patient quality of life and alleviating caregiver burden. However, individuals with FTD often face barriers to care due to limited insur…

Building Trust for Community-Engaged Research: Recommendations From a Qualitative Study Open

Thi Phuong Thao Tran, Jacque-Corey Cormier, Corey Anthony Hopwood, Jordan Foster, Isabel Scheib , et al. · 2025

Background Community engagement is crucial for public health research and detailed, step-by-step best practices for fostering it are needed. This study aimed to identify barriers and facilitators for public health research in three underse…

Alzheimer's disease blood-based biomarker testing: A stakeholder-informed assessment of coverage considerations Open

Patricia A. Deverka, Jalayne J. Arias, Grace A. Lin, Jessica Zwerling, Kathryn A. Phillips · 2025

Background Recently published clinical studies suggest that blood-based biomarker tests (BBMTs) for Alzheimer's disease (AD) provide value, but in the U.S., neither public nor private payers currently cover these tests. Objective To descri…

Barriers to and facilitators of clinician acceptance and use of artificial intelligence in healthcare settings: a scoping review Open

Catherine E. A. Scipion, Margaret A Manchester, Alex D. Federman, Yufei Wang, Jalayne J. Arias · 2025

Objectives This study aimed to systematically map the evidence and identify patterns of barriers and facilitators to clinician artificial intelligence (AI) acceptance and use across the types of AI healthcare application and levels of inco…

Artificial intelligence as a tool for cognitive impairment screening: Patient perspectives about benefits and limitations Open

Heather M. Wurtz, Heather M. Wurtz, Tatyana Valteau, Hugo H. Hanson, Catherine Scipion , et al. · 2025

Introduction This paper presents findings from a qualitative study exploring the perspectives of primary care patients on the use of artificial intelligence (AI) to synthesize data from the electronic medical record (EMR) and audio recordi…

“Atlanta Is Like Wakanda … but With Real Big, Big Issues” Open

Thi Phuong Thao Tran, Jeremiah Menyongai, Jordan Foster, Isabel Scheib, Ashley Kay Allen , et al. · 2025

Background and Objectives: This qualitative study explored perceived community strengths and health issues among 3 underserved and under-studied populations in the Atlanta, Georgia—older adults, Black or African American persons, and refug…

Guidance for clinical management of pathogenic variant carriers at elevated genetic risk for ALS/FTD Open

Michael Benatar, Terry Heiman‐Patterson, Johnathan Cooper‐Knock, Daniel Brickman, Kaitlin B. Casaletto , et al. · 2024

There is a growing understanding of the presymptomatic stages of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) and nascent efforts aiming to prevent these devastating neurodegenerative diseases have emerged. This pr…

How to Advance Legal Education for Future Public Health Professionals. Open

Micah L. Berman, Jalayne J. Arias, Nessia Berner Wong, Jami Crespo, Daniel S. Goldberg , et al. · 2024

Recent scholarship has advocated for schools and programs of public health (SPPHs) to move public health law from the periphery to the core of the public health curriculum, in recognition of law’s role as a fundamental driver of health out…

How to Advance Legal Education for Future Public Health Professionals Open

Micah L. Berman, Jalayne J. Arias, Nessia Berner Wong, Jami Crespo, Daniel S. Goldberg , et al. · 2024

Publisher Correction: The Miami Framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology Open

Michael Benatar, Joanne Wuu, Edward D. Huey, Corey T. McMillan, Ronald C. Petersen , et al. · 2024

The Miami Framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology Open

Michael Benatar, Joanne Wuu, Edward D. Huey, Corey T. McMillan, Ronald C. Petersen , et al. · 2024

Data stewardship in FTLD research: Investigator and research participant views Open

Jalayne J. Arias, Ana Tyler, Laura M. Beskow, Maria C. Carillo, Susan Dickinson , et al. · 2024

INTRODUCTION Federal policies and guidelines have expanded the return of individual results to participants and expectations for data sharing between investigators and through repositories. Here, we report investigators’ and study particip…

JME volume 52 issue 1 Cover and Front matter Open

James G. Hodge, Erica N. White, Jennifer L. Piatt, C. Laude, Amanda Buster , et al. · 2024

Crime, Dementia, and Caregivers: Keeping individuals with dementia out of the criminal justice system Open

Lillian Morgado, Jalayne J. Arias, Ana Tyler · 2023

Background The care and management of justice‐involved persons living with dementia (PLWD) are understudied. Yet emerging data indicate that PLWD may experience symptoms and behaviors which may lead to encounters with the criminal justice …

Forgotten and without Protections: Older Adults in Prison Settings Open

Jalayne J. Arias, Lillian Morgado, Stephanie Grace Prost · 2023

The number of older adults incarcerated in prisons is growing significantly, and there is a great need for legal authority, processes, and resources to mitigate individual and social burdens of elder neglect and abuse within these settings…

Out-of-Pocket Expenses for Long-Term Care by Dementia Status and Residential Setting among US Older Adults Open

Jing Li, Hannah Bancroft, Krista L. Harrison, Julia Van Deusen Fox, Ana Tyler , et al. · 2023

Crime, Incarceration, and Dementia: An Aging Criminal System Open

Jalayne J. Arias, Lillian Morgado, Ana Tyler · 2023

Dementia within the criminal system, from arrest through incarceration, has been largely ignored. While the health system has begun grappling with the chronic conditions that will accompany an aging society, the criminal system has yet to …

The Advisory Group on Risk Evidence Education for Dementia: Multidisciplinary and Open to All Open

Allyson Rosen, Jalayne J. Arias, J. Wesson Ashford, Deborah Blacker, Jasmeer P. Chhatwal , et al. · 2022

The brain changes of Alzheimer’s disease and other degenerative dementias begin long before cognitive dysfunction develops, and in people with subtle cognitive complaints, clinicians often struggle to predict who will develop dementia. The…

Geriatricians’ Perspectives on the Multiple Dimensions of Utility of Genetic Testing for Alzheimer’s Disease: A Qualitative Study Open

Jalayne J. Arias, Grace A. Lin, Ana Tyler, Michael P. Douglas, Kathryn A. Phillips · 2022

Background: Research advancements in Alzheimer’s disease (AD) raise opportunities for genetic testing to improve diagnostic and risk assessment. Despite emerging developments, it is unclear how geriatricians perceive the potential clinical…

Standardized outcome measures of mental health in research with older adults who are incarcerated Open

Stephanie Grace Prost, Cynthia Golembeski, Vyjeyanthi S. Periyakoil, Jalayne J. Arias, Andrea K. Knittel , et al. · 2022

Purpose The targeted use of standardized outcome measures (SOMs) of mental health in research with older adults who are incarcerated promotes a common language that enables interdisciplinary dialogue, contributes to the identification of d…

Preventing amyotrophic lateral sclerosis: insights from pre-symptomatic neurodegenerative diseases Open

Michael Benatar, Joanne Wuu, Caroline McHutchison, Ronald B. Postuma, Bradley F. Boeve , et al. · 2021

Significant progress has been made in understanding the pre-symptomatic phase of amyotrophic lateral sclerosis. While much is still unknown, advances in other neurodegenerative diseases offer valuable insights. Indeed, it is increasingly c…

Developing an Economic and Policy Research Agenda for Blood Biomarkers of Neurodegenerative Diseases Open

Jalayne J. Arias, Kathryn A. Phillips, Jason Karlawish · 2021

In the past 2 decades, researchers have discovered biomarkers for the pathologic causes of neurodegeneration, such as β-amyloid (Aβ) and tau associated with Alzheimer disease and dopamine identified through DaTscan imaging to confirm Parki…

Private payer coverage policies for ApoE-e4 genetic testing Open

Jalayne J. Arias, Ana Tyler, Michael P. Douglas, Kathryn A. Phillips · 2021

A Qualitative Analysis of Ethical Perspectives on Recruitment and Consent for Human Intracranial Electrophysiology Studies Open

Joncarmen V. Mergenthaler, Winston Chiong, Daniel Dohan, Josh Feler, Cailin R. Lechner , et al. · 2021

Intracranial electrophysiological research methods, including those applying electrodes on the cortical surface or in deep structures, have become increasingly important in human neuroscience. They also pose novel ethical concerns, as huma…

The formation of the advisory group on risk evaluation education for dementia Open

Allyson Rosen, Jessica Alber, Omar Al‐Janabi, Jalayne J. Arias, Shoshana H. Bardach , et al. · 2020

Background When and how to communicate effectively the results of genetic and biomarker based prediction, detection, and quantification of the brain substrates of dementia involve important ethical and legal issues critical for precision m…

A Matter of Intent: A Social Obligation to Improve Criminal Procedures for Individuals with Dementia Open

Jalayne J. Arias, Lauren Sydney Flicker · 2020

The relationship between dementia and criminal behavior perplexes legal and health care systems. Dementia is a progressive clinical syndrome defined by impairment in at least two cognitive domains that interferes with one's activities of d…

O2‐06‐02: FINANCIAL, LEGAL, AND SOCIAL DECISION‐MAKING IN EARLY‐ONSET ALZHEIMER'S DISEASE Open

Jalayne J. Arias, Krystal Karunungan, Kiran Chaudhary, Julie Pham, Taylor J. Mellinger , et al. · 2019

Individuals with early-onset Alzheimer's disease (EOAD, age-of-onset < 65 years old) are likely to experience unique challenges with financial, legal, and social decision-making following their diagnosis. Yet, there are limited data charac…

Alzheimer's disease biomarkers: another tool for FAA pilot screening? Open

Matthew W. Lawrence, Jalayne J. Arias · 2019

Research advancements to improve the accuracy of diagnosing Alzheimer's disease (AD) have altered clinicians and researchers’ understanding of the disease process. The discovery of amyloid and tau biomarkers as measures of disease patholog…

The Last Hope: How Starting Over Could Save Private Long-Term Care Insurance Open

Jalayne J. Arias · 2019

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