H. Turki
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The Role of HPV Vaccine in Preventing Cervical Cancer Open
Cervical cancer continues to be a significant health challenge worldwide, especially in resource-poor settings which account for over 90% of the deaths. Persistent infection with high-risk human papilloma virus (HPV) types, particularly HP…
Histopathological Evaluation of the Protective Effect of Nano-Curcumin on Adrenaline-Induced Myocardial Infarction in Rats Open
Myocardial infarction (MI), also referred to heart attacks, as are the leading cause of cardiovascular death in the majority of nations worldwide. MI is caused by blockage of one or more coronary arteries that supply blood to the heart. Th…
View article: Investigating the Expression of LL-37 Antimicrobial Peptide in Autoimmune Bullous Disorders: Implications for Pemphigus
Investigating the Expression of LL-37 Antimicrobial Peptide in Autoimmune Bullous Disorders: Implications for Pemphigus Open
Objective: This study aimed to investigate the expression of the antimicrobial peptide cathelicidin LL-37 and discuss its role as a critical factor in developing pemphigus. Methods: The expression of LL-37 mRNA was assessed in individuals …
View article: P-215 ROLE OF EXPOSURE TO ENVIRONMENTAL AND OCCUPATIONAL FACTORS IN THE OCCURRENCE OF PEMPHIGUS: A CASE-CONTROL STUDY IN TUNISIA
P-215 ROLE OF EXPOSURE TO ENVIRONMENTAL AND OCCUPATIONAL FACTORS IN THE OCCURRENCE OF PEMPHIGUS: A CASE-CONTROL STUDY IN TUNISIA Open
Introduction The pemphigus is a multifactorial dermatosis. While many etiological hypotheses have been suggested for its occurrence, the exact etiology remains to be determined.Our study aimed to identify the role of environmental and occu…
View article: Corrigendum: Current phenotypic and genetic spectrum of syndromic deafness in Tunisia: paving the way for precision auditory health
Corrigendum: Current phenotypic and genetic spectrum of syndromic deafness in Tunisia: paving the way for precision auditory health Open
[This corrects the article DOI: 10.3389/fgene.2024.1384094.].
View article: Current phenotypic and genetic spectrum of syndromic deafness in Tunisia: paving the way for precision auditory health
Current phenotypic and genetic spectrum of syndromic deafness in Tunisia: paving the way for precision auditory health Open
Hearing impairment (HI) is a prevalent neurosensory condition globally, impacting 5% of the population, with over 50% of congenital cases attributed to genetic etiologies. In Tunisia, HI underdiagnosis prevails, primarily due to limited ac…
View article: Congenital liquified subcutaneous fat necrosis in a newborn: an unusual case
Congenital liquified subcutaneous fat necrosis in a newborn: an unusual case Open
Subcutaneous fat necrosis of the newborn is a self-limited disorder of the panniculus that arises in the first six weeks of life. Some differential diagnoses may be difficult such as bacterial cellulitis or erysipelas. The prognosis is usu…
View article: Direct medical cost related to the management of pemphigus: A pilot Tunisian study
Direct medical cost related to the management of pemphigus: A pilot Tunisian study Open
Background: Pemphigus is a therapeutically challenging disease with high morbidity and economic burden. First-line prescription of rituximab remains limited in Tunisia due to its high cost. Systemic steroids remain the standard of care but…
View article: Follicular Basaloid Hamartoma and Associated Cutaneous Tumors: Clinical, Histopathological and Dermoscopic Aspects.
Follicular Basaloid Hamartoma and Associated Cutaneous Tumors: Clinical, Histopathological and Dermoscopic Aspects. Open
Several case reports have documented dermoscopic features of a solitary basaloid follicular hamartoma. However, further studies are required to specify any reproducible features.
View article: A longstanding tumor with toe deformity
A longstanding tumor with toe deformity Open
The authors declare no conflicts of interest. Data sharing is not applicable to this article as no new data were created or analyzed in this study.
View article: The Generalized Pustular Psoriasis Physician Global Assessment (GPPGA) score: online assessment and validation study of a specific measure of GPP disease activity
The Generalized Pustular Psoriasis Physician Global Assessment (GPPGA) score: online assessment and validation study of a specific measure of GPP disease activity Open
Generalized pustular psoriasis (GPP), a rare and potentially life-threatening neutrophilic skin disease, is characterized by recurrent flares of pustulation on nonacral skin with associated erythema, crusting and scaling. There are no agre…
View article: Unusual malar rash with ulceration: What can we expect?
Unusual malar rash with ulceration: What can we expect? Open
Considering the clinical polymorphism of the disease, longstanding skin lesions located on the face, resembling erysipelas in an endemic area should always be investigated for CL and thus, atypical presentations should be kept in mind.
View article: An unusual pigmented skin lesion on the nipple‐areola area
An unusual pigmented skin lesion on the nipple‐areola area Open
Considering the rarity and underdiagnoses of this disorder, a pigmented and hyperkeratotic skin lesion located on the trunk, resembling to acanthosis nigricans should always be investigated for terra firma‐forme dermatosis (TFFD) and thus …
View article: Unilateral hyperpigmented lesion of the breast
Unilateral hyperpigmented lesion of the breast Open
Muco‐cutaneous melanosis is a benign entity with no progression. Although, dermoscopic features may help to differentiate melanosis from malignant pigmented diseases, histopathology remains crucial for the confirming of melanosis of the ni…
View article: Trichofolliculoma: A Case Series.
Trichofolliculoma: A Case Series. Open
Trichofolliculoma (TF) is a rare benign adnexal follicular tumor, described as hamartoma with follicular differentiation according to some authors. It typically appears during adulthood on the face or scalp as an isolated nodule with protr…
View article: Bullous Pemphigoid Associated With Dipeptidyl Peptidase-4 Inhibitors: A Case Report and Review of Current Evidence
Bullous Pemphigoid Associated With Dipeptidyl Peptidase-4 Inhibitors: A Case Report and Review of Current Evidence Open
Dipeptidyl peptidase-4 inhibitors (DPP-4i), or gliptins, are a widely used glucose-lowering agents. A growing amount of evidence pointed to a possible role of DPP-4i in the induction of bullous pemphigoid (BP), which is an auto-immune skin…
View article: Whitish patches on the buccal mucosa: Role of dermoscopy
Whitish patches on the buccal mucosa: Role of dermoscopy Open
Morsicatio is caused by chronic self‐inflicted biting of the buccal mucosa that results in clinically whitish plaques. It is frequently confused with other dermatological mucosal disorders. To avoid needless invasive procedures, dermoscopy…
View article: Diagnostic challenge in a series of eleven patients with hyper IgE syndromes
Diagnostic challenge in a series of eleven patients with hyper IgE syndromes Open
Hyper IgE syndromes (HIES) is a heterogeneous group of Inborn Errors of Immunity characterized by eczema, recurrent skin and lung infections associated with eosinophilia and elevated IgE levels. Autosomal dominant HIES caused by loss of fu…
View article: Bilateral second branchial cleft fistulae coexisting with bilateral cleft lip and bilateral supra‐auricular fissures
Bilateral second branchial cleft fistulae coexisting with bilateral cleft lip and bilateral supra‐auricular fissures Open
A 4-month-old girl was referred to the dermatology department for bilateral branchial cleft fistula. She was a preterm baby. There was no history of consanguinity. A physical examination found a bilateral cleft lip (Figure 1), and a bilate…
Supplementary Material for: Clinical Characteristics and Outcomes of Generalized Pustular Psoriasis (GPP) Flares Open
Background: Generalized pustular psoriasis (GPP) is a rare, neutrophilic skin disease that can become life-threatening if flares are untreated. There are limited data describing the characteristics and clinical course of GPP disease flares…
View article: Inverted Follicular Keratosis
Inverted Follicular Keratosis Open
Inverted follicular keratosis (IFK) is a rare benign tumour of the follicular infundibulum characterized by exo-endophytic growing. Generally, the diagnosis of IFK is histopathologically made because clinical differentiation from other les…
View article: Late onset of flesh‐colored papules of the neck
Late onset of flesh‐colored papules of the neck Open
Papular elastorrhexis is a rare, acquired disorder of elastic tissue, occurring in adolescent females, characterized by flesh‐colored monomorphous papules usually located on the trunk and the proximal portion of the extremities. We report …
Clinical Characteristics and Outcomes of Generalized Pustular Psoriasis Flares Open
Background: Generalized pustular psoriasis (GPP) is a rare, neutrophilic skin disease that can become life-threatening if flares are untreated. There are limited data describing the characteristics and clinical course of GPP disease flares…