Jamel Ali
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View article: Transcriptomic analyses of normal human pancreata reveal the presence of cancer subtypes that correlate with acinar ductal metaplasia and donor ancestry
Transcriptomic analyses of normal human pancreata reveal the presence of cancer subtypes that correlate with acinar ductal metaplasia and donor ancestry Open
Molecular subtypes exist in pancreatic ductal adenocarcinoma (PDAC), however comparable subtypes are not known to exist in normal pancreas. A large, racially diverse cohort of normal, human pancreatic acinar cells were obtained from islet …
View article: Control of Gliding Motility and <i>C. lytica</i> Biofilm Iridescence via Substrate Mechanics
Control of Gliding Motility and <i>C. lytica</i> Biofilm Iridescence via Substrate Mechanics Open
Structural coloration in biological systems arises from the interaction of light with micro‐ and nanoscale structures, producing vivid, pigment‐free optical effects. While this phenomenon is well‐documented in butterflies and birds, recent…
View article: Recent Advances in Rare Earth Element Recovery: Liquid–Liquid Extraction and Magnetophoretic Separation
Recent Advances in Rare Earth Element Recovery: Liquid–Liquid Extraction and Magnetophoretic Separation Open
The unique physicochemical properties of rare earth elements (REEs) make them imperative for the production and improvement of advanced technology, renewable energy, and national defense applications. As these fields rapidly develop, there…
View article: Magnetophoresis of Weakly Magnetic Nanoparticle Suspension Around a Wire
Magnetophoresis of Weakly Magnetic Nanoparticle Suspension Around a Wire Open
We present a combined experimental and numerical study into the magnetophoresis behavior of weakly magnetic nanoparticle suspensions in the vicinity of a wire under a non-uniform magnetic field and negligible inertia. The experiments were …
View article: Magnetophoresis of paramagnetic nanoparticles in suspensions under magnetic field gradients
Magnetophoresis of paramagnetic nanoparticles in suspensions under magnetic field gradients Open
We systematically investigate the magnetophoresis of weakly paramagnetic manganese oxide nanoparticles under nonuniform magnetic fields using a combination of experiments and multiphysics numerical simulations. Experiments were conducted i…
View article: Dynamics of Transition Metal Ion Transport in High-Gradient Magnetic Fields
Dynamics of Transition Metal Ion Transport in High-Gradient Magnetic Fields Open
Magnetic separation has emerged as an eco-friendly and sustainable technique with applications in water purification, chemical separation, biochemical, medical, and mining. In this study, we present, a combined experimental and theoretical…
View article: Implantation of Islets Co-Seeded with Tregs in a Novel Biomaterial Reverses Diabetes in the NOD Mouse Model
Implantation of Islets Co-Seeded with Tregs in a Novel Biomaterial Reverses Diabetes in the NOD Mouse Model Open
Background: Type 1 diabetes (T1D) results in autoreactive T cells chronically destroying pancreatic islets. This often results in irreplaceable loss of insulin-producing beta cells. To reverse course, a combinatorial strategy of employing …
View article: Viscoelasticity of Hyaluronic Acid Hydrogels Regulates Human Pluripotent Stem Cell‐derived Spinal Cord Organoid Patterning and Vascularization
Viscoelasticity of Hyaluronic Acid Hydrogels Regulates Human Pluripotent Stem Cell‐derived Spinal Cord Organoid Patterning and Vascularization Open
Recently, it has been recognized that natural extracellular matrix (ECM) and tissues are viscoelastic, while only elastic properties have been investigated in the past. How the viscoelastic matrix regulates stem cell patterning is critical…
View article: Control of colloidal cohesive states in active chiral fluids
Control of colloidal cohesive states in active chiral fluids Open
Ensembles of suspended spinning particles in liquids form a distinct category of active matter systems known as chiral fluids. Recent experimental instances of dense chiral fluids have comprised of spinning colloidal magnets powered by an …
View article: Multiscale Fabrication and Rheological Characterization of Plant-Based Food Gels
Multiscale Fabrication and Rheological Characterization of Plant-Based Food Gels Open
Three-dimensional (3D) printing is an emerging additive manufacturing technology that uses computer-designed digital model files and various raw materials to construct objects through layer-by-layer addition. An important application of ad…
View article: Florida-California Cancer Research, Education and Engagement (CaRE <sup>2</sup> ) Health Equity Center: Structure, Innovations, and Initial Outcomes
Florida-California Cancer Research, Education and Engagement (CaRE <sup>2</sup> ) Health Equity Center: Structure, Innovations, and Initial Outcomes Open
Introduction The Florida-California Cancer Research, Education, and Engagement (CaRE 2 ) Health Equity Center is a triad partnership committed to increasing institutional capacity for cancer disparity research, the diversity of the cancer …
View article: Iron-enriched <i>Aspergillus oryzae</i> as an alternative to iron sulphate to limit iron accumulation, growth and motility of the enteric pathogen <i>S.</i> Typhimurium
Iron-enriched <i>Aspergillus oryzae</i> as an alternative to iron sulphate to limit iron accumulation, growth and motility of the enteric pathogen <i>S.</i> Typhimurium Open
Excess unabsorbed iron in the gastrointestinal tract may select for enteric pathogens and increase the incidence and severity of infectious disease. Aspergillus oryzae ( Ao ) is a filamentous fungus that has the ability to accumulate and s…
View article: Passive and Active Microrheology for Biomedical Systems
Passive and Active Microrheology for Biomedical Systems Open
Microrheology encompasses a range of methods to measure the mechanical properties of soft materials. By characterizing the motion of embedded microscopic particles, microrheology extends the probing length scale and frequency range of conv…
View article: Iron deficient diets modify the gut microbiome and reduce the severity of enteric infection in a mouse model of S. Typhimurium-induced enterocolitis
Iron deficient diets modify the gut microbiome and reduce the severity of enteric infection in a mouse model of S. Typhimurium-induced enterocolitis Open
Enteric infections are widespread in infants and children living in low-resource settings. Iron availability in the gastrointestinal tract may modify the gut microbiome and impact the incidence and severity of enteropathy. This study was d…
View article: Propulsion of magnetically actuated achiral planar microswimmers in Newtonian and non-Newtonian fluids
Propulsion of magnetically actuated achiral planar microswimmers in Newtonian and non-Newtonian fluids Open
Magnetic achiral planar microswimmers can be massively fabricated at low cost and are envisioned to be useful for in vivo biomedical applications. To understand locomotion in representative in vivo environments, we investigated the swimmin…
View article: Symmetry breaking propulsion of magnetic microspheres in nonlinearly viscoelastic fluids
Symmetry breaking propulsion of magnetic microspheres in nonlinearly viscoelastic fluids Open
Microscale propulsion impacts a diverse array of fields ranging from biology and ecology to health applications, such as infection, fertility, drug delivery, and microsurgery. However, propulsion in such viscous drag-dominated fluid enviro…
View article: Effective antitumor activity of 5T4‐specific CAR‐T cells against ovarian cancer cells in vitro and xenotransplanted tumors in vivo
Effective antitumor activity of 5T4‐specific CAR‐T cells against ovarian cancer cells in vitro and xenotransplanted tumors in vivo Open
Ovarian cancer is considered to be the most lethal gynecologic malignancy, and despite the development of conventional therapies and new therapeutic approaches, the patient's survival time remains short because of tumor recurrence and meta…
View article: Insulator Based Dielectrophoresis: Micro, Nano, and Molecular Scale Biological Applications
Insulator Based Dielectrophoresis: Micro, Nano, and Molecular Scale Biological Applications Open
Insulator based dielectrophoresis (iDEP) is becoming increasingly important in emerging biomolecular applications, including particle purification, fractionation, and separation. Compared to conventional electrode-based dielectrophoresis (…
View article: µ-PIV Measurements of Flows Generated by Photolithography-Fabricated Achiral Microswimmers
µ-PIV Measurements of Flows Generated by Photolithography-Fabricated Achiral Microswimmers Open
Robotic micro/nanoswimmers can potentially be used as tools for medical applications, such as drug delivery and noninvasive surgery. Recently, achiral microswimmers have gained significant attention because of their simple structures, whic…
View article: Biotemplated flagellar nanoswimmers
Biotemplated flagellar nanoswimmers Open
In this article, a porous hollow biotemplated nanoscale helix that can serve as a low Reynolds number robotic swimmer is reported. The nanorobot utilizes repolymerized bacterial flagella from Salmonella typhimurium as a nanotemplate for bi…
View article: Bacteria-inspired nanorobots with flagellar polymorphic transformations and bundling
Bacteria-inspired nanorobots with flagellar polymorphic transformations and bundling Open
Wirelessly controlled nanoscale robots have the potential to be used for both in vitro and in vivo biomedical applications. So far, the vast majority of reported micro- and nanoscale swimmers have taken the approach of mimicking the rotary…
View article: On-Surface Locomotion of Particle Based Microrobots Using Magnetically Induced Oscillation
On-Surface Locomotion of Particle Based Microrobots Using Magnetically Induced Oscillation Open
The low Reynolds number condition presents a fundamental constraint on designing locomotive mechanisms for microscale robots. We report on the use of an oscillating magnetic field to induce on-surface translational motion of particle based…
View article: Fabrication and magnetic control of alginate-based rolling microrobots
Fabrication and magnetic control of alginate-based rolling microrobots Open
Advances in microrobotics for biological applications are often limited due to their complex manufacturing processes, which often utilize cytotoxic materials, as well as limitations in the ability to manipulate these small devices wireless…
View article: Fabrication and magnetic control of alginate-based cellular micro robots
Fabrication and magnetic control of alginate-based cellular micro robots Open
Event Abstract Back to Event Fabrication and magnetic control of alginate-based cellular micro robots Jamel Ali1, Yigong Liu1, Hoyeon Kim1, U Kei Cheang1, Wei Sun1 and Min Jun Kim1 1 Drexel University, Department of Mechanical Engineering …