Nicholas J. Bacon
YOU?
Author Swipe
View article: Development and Testing of an Owner‐Reported Outcome Measure of Clinical Signs and Quality of Life in Dogs Treated With Chemotherapy
Development and Testing of an Owner‐Reported Outcome Measure of Clinical Signs and Quality of Life in Dogs Treated With Chemotherapy Open
Cancer is a leading cause of mortality in older dogs. Despite the prevalence of chemotherapy in canine oncology, a good understanding of owners' observations of side effects and clinical signs in real time is still lacking. Owners' percept…
View article: Use of porcine small intestinal submucosa for reconstruction of a soft palate defect following marginal resection of a melanoma in a dog
Use of porcine small intestinal submucosa for reconstruction of a soft palate defect following marginal resection of a melanoma in a dog Open
A 12‐year‐old castrated male golden retriever was referred for evaluation of a palatal mass. Computed tomography identified a 2.7 × 2.0 × 1.5 cm soft tissue mass extending from the caudal aspect of the hard palate to the rostral soft palat…
View article: Axillary lymph node removal for staging cancer; description of a lateral approach and application in 44 tumor‐bearing dogs
Axillary lymph node removal for staging cancer; description of a lateral approach and application in 44 tumor‐bearing dogs Open
Objective To describe a lateral approach for axillary lymph node (ALN) extirpation and evaluate complications in dogs with local malignant tumors. Study design Retrospective study. Animals A total of 44 dogs diagnosed with local malignanci…
View article: The Immune Contexture in Canine Anal Sac Adenocarcinoma: Immunohistochemical Quantification of Tumor-Infiltrating Lymphocytes and Tumor-Associated Macrophages with Image Analysis
The Immune Contexture in Canine Anal Sac Adenocarcinoma: Immunohistochemical Quantification of Tumor-Infiltrating Lymphocytes and Tumor-Associated Macrophages with Image Analysis Open
Canine anal sac gland adenocarcinomas (ASACs) are locally aggressive and highly metastatic to regional lymph nodes. Tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) can be effective prognostic and predictive ma…
View article: Keeping Pathologists in the Loop and an Adaptive F1-Score Threshold Method for Mitosis Detection in Canine Perivascular Wall Tumours
Keeping Pathologists in the Loop and an Adaptive F1-Score Threshold Method for Mitosis Detection in Canine Perivascular Wall Tumours Open
Performing a mitosis count (MC) is the diagnostic task of histologically grading canine Soft Tissue Sarcoma (cSTS). However, mitosis count is subject to inter- and intra-observer variability. Deep learning models can offer a standardisatio…
View article: Intrahepatic splenosis as a differential diagnosis for hepatic neoplasia in a dog
Intrahepatic splenosis as a differential diagnosis for hepatic neoplasia in a dog Open
Intrahepatic splenosis is the heterotopic autotransplantation of splenic tissue secondary to splenic trauma or splenectomy. A 12‐year‐old Cairn terrier was referred due to lethargy, collapse and abdominal discomfort. Abdominal ultrasound a…
View article: Relationship between magnetic resonance imaging findings and histological grade in spinal peripheral nerve sheath tumors in dogs
Relationship between magnetic resonance imaging findings and histological grade in spinal peripheral nerve sheath tumors in dogs Open
Background Peripheral nerve sheath tumors (PNSTs) are a group of neoplasms originating from Schwann cells or pluripotent cell of the neural crest. Therapeutic options and prognosis are influenced by their degree of malignancy and location.…
View article: Atomic Resolution SE Imaging in a 30-200 keV Aberration-corrected UHV STEM
Atomic Resolution SE Imaging in a 30-200 keV Aberration-corrected UHV STEM Open
Journal Article Atomic Resolution SE Imaging in a 30-200 keV Aberration-corrected UHV STEM Get access M T Hotz, M T Hotz Nion R&D, 11511 NE 118th St, Kirkland, WA, USA Search for other works by this author on: Oxford Academic Google Schola…
View article: Detection of Necrosis in Digitised Whole-Slide Images for Better Grading of Canine Soft-Tissue Sarcomas Using Machine-Learning
Detection of Necrosis in Digitised Whole-Slide Images for Better Grading of Canine Soft-Tissue Sarcomas Using Machine-Learning Open
The definitive diagnosis of canine soft-tissue sarcomas (STSs) is based on histological assessment of formalin-fixed tissues. Assessment of parameters, such as degree of differentiation, necrosis score and mitotic score, give rise to a fin…
View article: Intraoperative cell salvaging: ex vivo evaluation of two swab-washing methods
Intraoperative cell salvaging: ex vivo evaluation of two swab-washing methods Open
OBJECTIVE To compare erythrocyte recovery by a cell salvage device between swab-washing by manual agitation or filtration. SAMPLE 12 recently expired units of canine packed RBCs. PROCEDURE The packed RBC units underwent quality analysis be…
View article: Comparison of efficacy in red blood cell recovery from swab washing using two different techniques - ex vivo study
Comparison of efficacy in red blood cell recovery from swab washing using two different techniques - ex vivo study Open
Clinical abstract presented at BSAVA Congress 2022. See full text for abstract and see clinical abstract sessions for a recording of the presentation. Abstracts are presented as supplied and have not been edited.
View article: Evaluation efficacy of a novel cell salvage device with canine blood and following swab washing - ex vivo study
Evaluation efficacy of a novel cell salvage device with canine blood and following swab washing - ex vivo study Open
Clinical abstract presented at BSAVA Congress 2022. See full text for abstract and see clinical abstract sessions for a recording of the presentation. Abstracts are presented as supplied and have not been edited.
View article: Deep Learning for Necrosis Detection Using Canine Perivascular Wall Tumour Whole Slide Images
Deep Learning for Necrosis Detection Using Canine Perivascular Wall Tumour Whole Slide Images Open
Necrosis seen in histopathology Whole Slide Images is a major criterion that contributes towards scoring tumour grade which then determines treatment options. However conventional manual assessment suffers from inter-operator reproducibili…
View article: Toxicity of zoledronic acid after intravenous administration: A retrospective study of 95 dogs
Toxicity of zoledronic acid after intravenous administration: A retrospective study of 95 dogs Open
Background There is a paucity of veterinary literature on the safety or outcome of zoledronic acid (ZA) use in dogs for either bone pain or hypercalcemia. Hypothesis/Objectives The primary aim was to report the adverse events in dogs recei…
View article: Session 7: Oncology
Session 7: Oncology Open
Oral presentations given during the BSAVA Abstract sessions 24-26 May 2021. Does homeopathy extend survival time in dogs with osteosarcoma: preliminary findings; Retrospective analysis of the metastatic behaviour of anal sac adenocarcinoma…
View article: Mapping lymph nodes: the whys and the wherefores
Mapping lymph nodes: the whys and the wherefores Open
Preview this chapter: Mapping lymph nodes: the whys and the wherefores, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/10.22233/9781910443774/9781910443774.16.7-1.gif
View article: The toxicity profile of zoledronic acid in dogs — a single centre retrospective study
The toxicity profile of zoledronic acid in dogs — a single centre retrospective study Open
Preview this chapter: The toxicity profile of zoledronic acid in dogs — a single centre retrospective study, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/10.22233/9781910443774/9781910443774.64.2-1.gif
View article: Difficult mast cell tumours and dirty margins
Difficult mast cell tumours and dirty margins Open
Preview this chapter: Difficult mast cell tumours and dirty margins, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/10.22233/9781910443774/9781910443774.13.3-1.gif
View article: Oral tumours: advanced
Oral tumours: advanced Open
Preview this chapter: Oral tumours: advanced, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/10.22233/9781910443774/9781910443774.16.6-1.gif
View article: Oral tumours: basic
Oral tumours: basic Open
Preview this chapter: Oral tumours: basic, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/10.22233/9781910443774/9781910443774.16.5-1.gif
View article: Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation
Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation Open
Gene expression profiling has revealed molecular heterogeneity of diffuse large B cell lymphoma (DLBCL) in both humans and dogs. Two DLBCL subtypes based on cell of origin are generally recognized, germinal center B (GCB)-like and activate…
View article: Intranasal proliferative fibro-osseous dysplasia in a domestic longhair cat
Intranasal proliferative fibro-osseous dysplasia in a domestic longhair cat Open
Case summary A 13-year-old female domestic longhair cat was presented for further investigation of chronic sneezing combined with a right-sided nasal discharge. A CT scan of the head revealed a locally invasive, aggressive right nasal mass…
View article: Outcomes of eight cats with oral neoplasia treated with radical mandibulectomy
Outcomes of eight cats with oral neoplasia treated with radical mandibulectomy Open
Objective To report outcomes after radical mandibulectomy in cats. Study design Multi‐institutional retrospective study. Animals Eight cats were included. Methods Medical records were searched for cats with confirmed oral neoplasia treated…
View article: Advances in STEM and EELS: New Operation Modes, Detectors and Software
Advances in STEM and EELS: New Operation Modes, Detectors and Software Open
Advances in the capabilities of scanning transmission electron microscopes (STEMs) and electron energy loss spectrometers (EELS) over the last 2 decades have been remarkable.Modern-day monochromated, aberration corrected STEMs (MAC-STEMs) …
View article: Hemipelvectomy in a rabbit: surgical technique and outcome
Hemipelvectomy in a rabbit: surgical technique and outcome Open
Preview this chapter: Hemipelvectomy in a rabbit: surgical technique and outcome, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/10.22233/9781910443699/9781910443699.85.29-1.gif
View article: Ultra-High Energy Resolution EELS
Ultra-High Energy Resolution EELS Open
The High Energy Resolution Monochromated EELS-STEM (HERMES) system developed by Nion combines a ground-potential monochromator, a bright cold-field-emission (CFE) gun, an advanced aberration corrector, and a new EEL spectrometer.The system…
View article: The use of complementary and alternative therapies in dogs and cats with cancer in the UK
The use of complementary and alternative therapies in dogs and cats with cancer in the UK Open
Preview this chapter: The use of complementary and alternative therapies in dogs and cats with cancer in the UK, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/10.22233/9781910443439/9781910443439.70.5-1.gif