James Bena
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View article: SAT-465 Metabolic and Clinical Characteristics of Patients with Mild Autonomous Cortisol Secretion: A Retrospective Analysis of Adrenal Incidentalomas in a Referral Center
SAT-465 Metabolic and Clinical Characteristics of Patients with Mild Autonomous Cortisol Secretion: A Retrospective Analysis of Adrenal Incidentalomas in a Referral Center Open
Disclosure: M. Eldib: None. N. Fretes Oviedo: None. V. Mendpara: None. J. Bena: None. P.P. Rao: None. R. Correa: None. Introduction: Mild Autonomous Cortisol Secretion (MACS) is characterized by abnormal circadian rhythm secretion of corti…
View article: Macrovascular and microvascular outcomes of metabolic surgery versus GLP-1 receptor agonists in patients with diabetes and obesity
Macrovascular and microvascular outcomes of metabolic surgery versus GLP-1 receptor agonists in patients with diabetes and obesity Open
View article: 0818 Discrepancy Between Clinical Phenotyping and ICSD-3 Criteria Contributes to Misdiagnosis in Central Disorders of Hypersomnolence
0818 Discrepancy Between Clinical Phenotyping and ICSD-3 Criteria Contributes to Misdiagnosis in Central Disorders of Hypersomnolence Open
Introduction Central Disorders of Hypersomnolence (CDH) are classified primarily by polysomnography-multiple sleep latency test (PSG-MSLT). Lack of biomarkers, variable MSLT results in disorders other than narcolepsy type 1 (NT1) and inacc…
View article: 1236 Impact of Medication Use on REM Sleep Without Atonia: Differentiating Medication Effect from Depression Diagnosis
1236 Impact of Medication Use on REM Sleep Without Atonia: Differentiating Medication Effect from Depression Diagnosis Open
Introduction REM Sleep without Atonia (RSWA) is the polysomnographic biomarker of REM Sleep Behavior Disorder (RBD). RSWA is associated with serotonergic (SSRIs/SNRIs) antidepressants (ADs). The effects of other ADs and depression on RSWA …
View article: 1142 Estimating Influence of the Run-In Period on Statistical Power in a Randomized Clinical Trial of OSA and CPAP
1142 Estimating Influence of the Run-In Period on Statistical Power in a Randomized Clinical Trial of OSA and CPAP Open
Introduction A run-in period is sometimes used in randomized clinical trials to exclude non-adherent participants, yet its influence on adherence and statistical power remains underexplored in obstructive sleep apnea (OSA) trials with cont…
View article: 1099 Sleep Apnea-Specific Hypoxic Burden as a Predictor of Incident Heart Failure Compared to Traditional Measures
1099 Sleep Apnea-Specific Hypoxic Burden as a Predictor of Incident Heart Failure Compared to Traditional Measures Open
Introduction Apnea hypopnea index (AHI) is the prevailing measure of obstructive sleep apnea (OSA) presence and severity. Despite numerous consequences, AHI calculation measures only frequency of respiratory events. Measures which characte…
View article: 1121 Post-Discharge Telemedicine Motivational Enhancement in Acute Decompensated Heart Failure and Obstructive Sleep Apnea Randomized Clinical Trial
1121 Post-Discharge Telemedicine Motivational Enhancement in Acute Decompensated Heart Failure and Obstructive Sleep Apnea Randomized Clinical Trial Open
Introduction Adherence to Positive Airway Pressure (PAP) in patients with Acute Decompensated Heart Failure (ADHF) and Obstructive Sleep Apnea (OSA) is associated with improved outcomes. However, follow-up with long-term PAP adherence pose…
View article: 0801 Polysomnographic Characteristics Differentiating the Central Disorders of Hypersomnolence
0801 Polysomnographic Characteristics Differentiating the Central Disorders of Hypersomnolence Open
Introduction Central Disorders of Hypersomnolence (CDH) are classified primarily by polysomnography-multiple sleep latency test (PSG-MSLT). Lack of biomarkers and variable MSLT results in disorders other than narcolepsy type 1 (NT1) contri…
View article: 1120 Impact of Post-Metabolic Surgery Weight Loss on Relationship of Sleep Disordered Breathing and Cardiovascular Events
1120 Impact of Post-Metabolic Surgery Weight Loss on Relationship of Sleep Disordered Breathing and Cardiovascular Events Open
Introduction Obstructive sleep apnea (OSA) and obesity hypoventilation syndrome (OHS) are known risk factors for major adverse cardiovascular events (MACE): coronary artery disease, cerebrovascular events, heart failure, atrial fibrillatio…
View article: 0870 Shift Work Disorder Prevalence and Associated Characteristics Using the Mobile Application SLEEP by Cleveland Clinic™
0870 Shift Work Disorder Prevalence and Associated Characteristics Using the Mobile Application SLEEP by Cleveland Clinic™ Open
Introduction Shift Work Disorder (SWD) arises from recurring work schedules overlapping typical sleep times. SWD is associated with increased risks of medical and psychiatric disorders with estimated prevalence of 2-5%, likely to be undere…
View article: 1096 Age- and Sex-Specific Relationship of Sleep Apnea-Specific Heart Rate Response and Atrial Fibrillation Incidence
1096 Age- and Sex-Specific Relationship of Sleep Apnea-Specific Heart Rate Response and Atrial Fibrillation Incidence Open
Introduction Autonomic dysfunction (AD) is implicated in sleep apnea and atrial fibrillation (AF), however age- and sex-specific interactions are unclear. We hypothesize age- and sex-specific differences in sleep apnea-specific heart rate …
View article: Impact of a multidisciplinary sleep apnea management group clinic on positive airway pressure adherence and patient-reported outcomes: a randomized controlled trial
Impact of a multidisciplinary sleep apnea management group clinic on positive airway pressure adherence and patient-reported outcomes: a randomized controlled trial Open
View article: Rapidly Fatal Metastatic Cholangiocarcinoma Associated With Metabolic Dysfunction–Associated Steatotic Liver Disease and Metabolic Syndrome: A Case Report Highlighting Emerging Risk Factors
Rapidly Fatal Metastatic Cholangiocarcinoma Associated With Metabolic Dysfunction–Associated Steatotic Liver Disease and Metabolic Syndrome: A Case Report Highlighting Emerging Risk Factors Open
Cholangiocarcinoma (CCA), a rare biliary cancer, typically presents with nonspecific symptoms that hinder early diagnosis. Emerging metabolic risk factors are increasingly being recognized as contributors. We present the case of a 54-year-…
View article: Differences in Gastrointestinal Motility in Adults with Type 1 and Type 2 Diabetes Using Wireless Motility Capsule
Differences in Gastrointestinal Motility in Adults with Type 1 and Type 2 Diabetes Using Wireless Motility Capsule Open
View article: Benign Prostatic Hyperplasia Knowledge Deficits Among Male Urology Patients
Benign Prostatic Hyperplasia Knowledge Deficits Among Male Urology Patients Open
There remain significant knowledge gaps about BPH among men seeking urologic care. Education tools for both patients and primary care physicians may help improve health literacy as well as health outcomes for patients with BPH.
View article: Feasibility and staff acceptability of implementing Xpert HIV-1 viral load point-of-care testing: a pilot study in San Francisco
Feasibility and staff acceptability of implementing Xpert HIV-1 viral load point-of-care testing: a pilot study in San Francisco Open
Background Point-of-care HIV viral load testing may enhance patient care and improve HIV health services. We aimed to evaluate the feasibility and acceptability of implementing such testing in a high-volume community sexual health clinic i…
View article: Differences in Gastrointestinal Motility in Adults with Type 1 and Type 2 Diabetes Using Wireless Motility Capsule
Differences in Gastrointestinal Motility in Adults with Type 1 and Type 2 Diabetes Using Wireless Motility Capsule Open
PURPOSE: Gastrointestinal motility disorders are common in diabetes, though their prevalence and distribution are unclear. The Wireless Motility Capsule (WMC) assesses transit times and pressures of the entire gastrointestinal tract in a s…
View article: Initial symptoms in individuals with Alzheimer’s or mixed Alzheimer’s‐Lewy body dementia are noted at an older age and are more likely to be amnestic in African Americans than Whites
Initial symptoms in individuals with Alzheimer’s or mixed Alzheimer’s‐Lewy body dementia are noted at an older age and are more likely to be amnestic in African Americans than Whites Open
Background Amnestic initial symptoms are common in Alzheimer’s disease(AD). However initial non‐amnestic (language, executive or visuospatial) symptoms are seen in ∼20% and associated with faster progression. Given racial differences in cl…
View article: Does type of anesthesia during procedural management of suspected renal colic during pregnancy have an impact on preterm birth?
Does type of anesthesia during procedural management of suspected renal colic during pregnancy have an impact on preterm birth? Open
Introduction: Anesthesia choice during the procedural management of suspected renal colic during pregnancy may vary based on available resources and patient or provider preferences, as there are no specific recommendations. Our objective w…
View article: 12603 The Effect Of Telemedicine On Glycemic Control In Patients With Type 2 Diabetes
12603 The Effect Of Telemedicine On Glycemic Control In Patients With Type 2 Diabetes Open
Disclosure: D. Salih Bacha: None. K. Alkwatli: None. H. Xiao: None. J. Bena: None. P.P. Rao: None. Introduction: The COVID-19 pandemic accelerated the adoption of telemedicine, expanding access to healthcare services for patients and provi…
View article: 5040 Leveraging Continuous Glucose Monitoring Data as an Additional Source for Glucagon Prescription Behavior
5040 Leveraging Continuous Glucose Monitoring Data as an Additional Source for Glucagon Prescription Behavior Open
Disclosure: J. Ambalavanan: None. J. Rusticelli: None. D. Isaacs: Consulting Fee; Self; Medtronic Diabetes, Lilly USA, LLC, Novo Nordisk, Insulet Corporation, Abbott Laboratories, Dexcom. H. Xiao: None. J. Bena: None. Z. Jin: None. C. Babi…
View article: Real world challenges and barriers for positive airway therapy use in acute ischemic stroke patients
Real world challenges and barriers for positive airway therapy use in acute ischemic stroke patients Open
Purpose Untreated obstructive sleep apnea (OSA) in patients with acute ischemic stroke (AIS) is associated with increased morbidity and mortality. However, diagnosing and treating OSA in AIS is challenging. We aimed to determine the feasib…
View article: Clinical Outcomes in Patients With Hypocontractile Bladders Undergoing Holmium Laser Enucleation of the Prostate
Clinical Outcomes in Patients With Hypocontractile Bladders Undergoing Holmium Laser Enucleation of the Prostate Open
HoLEP can be an effective surgical option for BPH patients with hypocontractile bladders, including those who are catheter-dependent, with minimal differences in post-operative voiding parameters compared to those with normal bladder funct…
View article: Radiofrequency ablation versus microwave ablation for colorectal liver metastases: long-term results of a retrospective cohort surgical experience
Radiofrequency ablation versus microwave ablation for colorectal liver metastases: long-term results of a retrospective cohort surgical experience Open
This large study confirms our initial observation that local tumor control rate is better after MWA vs. RFA.
View article: The Long-Term Effect of Weight Loss on the Prevention of Progression to Cirrhosis among Patients with Obesity and MASH-Related F3 Liver Fibrosis
The Long-Term Effect of Weight Loss on the Prevention of Progression to Cirrhosis among Patients with Obesity and MASH-Related F3 Liver Fibrosis Open
This multi-center retrospective study examined the effect of weight loss on the prevention of progression to cirrhosis in a sample exclusively composed of patients with obesity and MASH-related F3 liver fibrosis. Adult patients with obesit…
View article: Changes in Emergency Department Utilization in Vulnerable Populations After COVID-19 Shelter-in-Place Orders
Changes in Emergency Department Utilization in Vulnerable Populations After COVID-19 Shelter-in-Place Orders Open
View article: Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia‐inducible factor‐1α in normoxia
Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia‐inducible factor‐1α in normoxia Open
Hypoxia‐inducible factor (HIF)‐1α is continuously synthesized and degraded in normoxia. During hypoxia, HIF1α stabilization restricts cellular/mitochondrial oxygen utilization. Cellular stressors can stabilize HIF1α even during normoxia. H…
View article: Not Entirely in Vein: Predictors of Progressive Chronic Venous Insufficiency and Mediators of Successful Endovenous Laser Ablation
Not Entirely in Vein: Predictors of Progressive Chronic Venous Insufficiency and Mediators of Successful Endovenous Laser Ablation Open
View article: An Obesity-Centric Approach with and Without Anti-Obesity Medications Compared to the Usual-Care Approach to Management of Patients with Obesity and Type 2 Diabetes in an Employer Setting: A Pragmatic Randomized Controlled Trial (EMPOWER-T2D)
An Obesity-Centric Approach with and Without Anti-Obesity Medications Compared to the Usual-Care Approach to Management of Patients with Obesity and Type 2 Diabetes in an Employer Setting: A Pragmatic Randomized Controlled Trial (EMPOWER-T2D) Open
View article: Issue Information
Issue Information Open