James M. Bjork
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Impulsivity-Related Predictors of Adolescent Substance Use Initiation Open
Background and Aims: Neurodevelopmental models regard impulsivity as a central risk factor for adolescent substance use and subsequent adverse health outcomes. However, prior research has been constrained by cross-sectional designs, relati…
Attitudinal Predictors of No-Show to Substance Use Disorder Treatment Intake in Veterans Open
Background: Substance use disorder (SUD) exacts a devastating psychosocial and medicolegal toll in Veterans. Despite the availability of quality SUD care provided by the Veterans Health Administration, many Veterans with SUD who initially …
View article: Machine Learning Applications Related to Suicide in Military and Veterans: A Scoping Literature Review
Machine Learning Applications Related to Suicide in Military and Veterans: A Scoping Literature Review Open
Suicide remains one of the main preventable causes of death among active service members and veterans. Early detection and prediction are crucial in suicide prevention. Machine learning techniques have yielded promising results in this are…
View article: Unintended bias in the pursuit of collinearity solutions in fMRI analysis
Unintended bias in the pursuit of collinearity solutions in fMRI analysis Open
In task functional magnetic resonance imaging (fMRI), collinearity between task regressors in time series models may impact power. When collinearity is identified after data collection, researchers often modify the model in an effort to re…
View article: Unintended bias in the pursuit of collinearity solutions in fMRI analysis
Unintended bias in the pursuit of collinearity solutions in fMRI analysis Open
In task functional magnetic resonance imaging (fMRI), collinearity between task regressors in time series models may impact power. When collinearity is identified after data collection, researchers often modify the model in an effort to re…
Transcending Self Therapy Virtual Reality Expansion: Effect on Engagement, Completion and Temporal Usage Patterns Open
Transcending Self Therapy (TST) is an integrative cognitive behavioral therapy for substance use disorders (SUDs) that was adapted into an immersive virtual reality (VR) platform (TST-VR) featuring psychoeducation modules, mindfulness exer…
Task-based effective connectivity finds alterations in frontoparietal network in Duchenne muscular dystrophy Open
Duchenne muscular dystrophy is a monogenic X-linked genetic disorder that is caused due to the absence of dystrophin. In addition to the skeletal and cardiac manifestations, challenges in executive function are pervasive and persistent, af…
Phase 1b/2a safety study of lemborexant as an adjunctive treatment for insomnia to buprenorphine-naloxone for opioid use disorder: A randomized controlled trial Open
Findings support the initial safety and tolerability of lemborexant as an adjunctive treatment for insomnia in humans receiving buprenorphine for OUD. Future longitudinal work is warranted with larger samples.
Neurocognitive function and medical care utilization in Veterans treated for substance use disorder Open
Background Veterans with substance use disorder (SUD) are at high risk for cognitive problems due to neurotoxic effects of chronic drug and alcohol use coupled in many cases with histories of traumatic brain injury (TBI). These problems ma…
Insomnia symptoms and neurofunctional correlates among adults receiving buprenorphine for opioid use disorder Open
Objectives Insomnia symptoms are negatively related to opioid use disorder (OUD) treatment outcomes, possibly reflecting the influence of sleep on neurofunctional domains implicated in addiction. Moreover, the intersection between OUD reco…
Transcending Self Therapy-Virtual Reality (TST-VR) and Substance Use Disorder (SUD) Treatment Completion in Veterans Open
Transcending Self Therapy (TST) is an integrative Cognitive Behavioral Therapy (CBT) for substance use disorders (SUD). Virtual reality (VR)-based enhancement of treatment for mental health disorders holds potential as an innovative and im…
View article: Parameter Space and Potential for Biomarker Development in 25 Years of fMRI Drug Cue Reactivity
Parameter Space and Potential for Biomarker Development in 25 Years of fMRI Drug Cue Reactivity Open
Importance In the last 25 years, functional magnetic resonance imaging drug cue reactivity (FDCR) studies have characterized some core aspects in the neurobiology of drug addiction. However, no FDCR-derived biomarkers have been approved fo…
Decision-Making and Management of Self-Care in Persons with Traumatic Spinal Cord Injuries: A Preliminary Study Open
Patients and physicians understand the importance of self-care following spinal cord injury (SCI), yet many individuals with SCI do not adhere to recommended self-care activities despite logistical supports. Neurobehavioral determinants of…
Virtual Hybrid Versus In-Person Administration of Transcending Self Therapy for Veterans with Substance Use Disorders Open
Objectives: Veterans with substance use disorder (SUD) can show high severity and are at high risk of relapse due to trauma histories and other comorbid conditions. However, evidence-based SUD therapies may not be available to many veteran…
Initial Validation of a Behavioral Phenotyping Model for Substance Use Disorder Open
Standard nosological systems, such as DSM-5 or ICD-10, are relied upon as the diagnostic basis when developing treatments for individuals with substance use disorder (SUD). Unfortunately, the vast heterogeneity of individuals within a give…
Relation of Aerobic Activity to Cognition and Well-being in Chronic Mild Traumatic Brain Injury: A LIMBIC-CENC Study Open
Introduction Because chronic difficulties with cognition and well-being are common after mild traumatic brain injury (mTBI) and aerobic physical activity and exercise (PAE) is a potential treatment and mitigation strategy, we sought to det…
Development and clinical feasibility study of a brief version of an addiction‐focused phenotyping battery in females receiving buprenorphine for opioid use disorder Open
Introduction We aimed to streamline the NIDA Phenotyping Assessment Battery (PhAB), a package of self‐report scales and neurobehavioral tasks used in substance use disorder (SUD) clinical trials, for clinical administration ease. Tailoring…
View article: Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection
Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection Open
Importance SARS-CoV-2 infection is associated with persistent, relapsing, or new symptoms or other health effects occurring after acute infection, termed postacute sequelae of SARS-CoV-2 infection (PASC), also known as long COVID . Charact…
Chronic Cocaine Use and White Matter Coherence: A Diffusion Tensor Imaging Study Open
These data align with previously reported declines in white matter coherence in chronic cocaine users. However, it is less clear whether comorbid alcohol consumption results in an additive deleterious effect on white matter microstructure.
View article: Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder
Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder Open
ClinicalTrials.gov Identifier: NCT03170362.