James Carrick
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View article: Fourteen years later: Reviewing the diagnostic criteria for behavioral‐variant frontotemporal dementia
Fourteen years later: Reviewing the diagnostic criteria for behavioral‐variant frontotemporal dementia Open
INTRODUCTION Diagnosis of behavioral‐variant frontotemporal dementia (bvFTD) requires the presence of at least three of six core features. The contribution of each criterion toward diagnosis, however, remains unclear. We aimed to determine…
View article: Coping With Primary Progressive Aphasia: Factors Predicting Caregiver Psychological Wellbeing and Burden
Coping With Primary Progressive Aphasia: Factors Predicting Caregiver Psychological Wellbeing and Burden Open
Background Impacts of dementia syndromes on caregivers are well established, but research specific to Primary Progressive Aphasia (PPA) populations is scant. In particular, little is known about the impacts of non‐language symptoms (e.g., …
View article: Survival rates in frontotemporal dementia and Alzheimer’s disease
Survival rates in frontotemporal dementia and Alzheimer’s disease Open
Our findings demonstrate distinct survival patterns across FTD and AD subtypes. Demographic and presenting clinical features provide valuable prognostic insights for survival.
View article: A Bayesian analysis of diagnostic timelines across Alzheimer's disease, frontotemporal dementia, and other neurodegenerative conditions
A Bayesian analysis of diagnostic timelines across Alzheimer's disease, frontotemporal dementia, and other neurodegenerative conditions Open
INTRODUCTION Timely diagnosis is crucial for managing neurodegenerative conditions. This study investigated whether time from symptom onset to diagnosis differs by clinical syndrome and sex. METHODS This retrospective, cross‐sectional stud…
View article: Interpreting Addenbrooke's Cognitive Examination‐<scp>III</scp> Scores in Dementia: Performance Distributions and Clinically Meaningful Change
Interpreting Addenbrooke's Cognitive Examination‐<span>III</span> Scores in Dementia: Performance Distributions and Clinically Meaningful Change Open
Background The Addenbrooke's Cognitive Examination‐III (ACE‐III) is a common cognitive screening measure. We provide performance deciles, descriptive performance bands and indices of reliable change between repeat assessments using the ACE…
View article: Discourse in primary progressive aphasia: Longitudinal changes and neural correlates
Discourse in primary progressive aphasia: Longitudinal changes and neural correlates Open
Background Primary progressive aphasia (PPA) is a neurodegenerative brain condition with three variants - nonfluent (nfvPPA), logopenic (lvPPA), semantic (svPPA). At onset, nfvPPA shows atrophy in left inferior frontal gyrus with grammatic…
View article: Cognitive profiles in primary progressive aphasia variants: A cross-cultural Australian and Spanish investigation
Cognitive profiles in primary progressive aphasia variants: A cross-cultural Australian and Spanish investigation Open
These findings revealed an impairment in other cognitive domains beyond language in PPA. However, Spanish patients exhibited more generalized cognitive involvement despite similar demographic and neuroimaging profiles, suggesting that cult…
View article: Differentiating sporadic frontotemporal dementia from late-onset primary psychiatric disorders
Differentiating sporadic frontotemporal dementia from late-onset primary psychiatric disorders Open
Sporadic behavioural variant frontotemporal dementia (bvFTD) is often misdiagnosed as late-onset primary psychiatric disorder (PPD) due to overlapping symptoms and lack of biomarkers. We aimed to identify clinical features that distinguish…
View article: Visuospatial working memory in behavioural variant frontotemporal dementia: a comparative analysis with Alzheimer's disease using the box task
Visuospatial working memory in behavioural variant frontotemporal dementia: a comparative analysis with Alzheimer's disease using the box task Open
Objective This study investigated the visuospatial working memory profiles of behavioural variant frontotemporal dementia (bvFTD) and Alzheimer’s disease (AD) using a novel computerised test of visuospatial working memory: the Box Task. Me…
View article: Electroencephalographic slowing during REM sleep in older adults with subjective cognitive impairment and mild cognitive impairment
Electroencephalographic slowing during REM sleep in older adults with subjective cognitive impairment and mild cognitive impairment Open
Study Objectives In older adults with Alzheimer’s disease, slowing of electroencephalographic (EEG) activity during REM sleep has been observed. Few studies have examined EEG slowing during REM in those with mild cognitive impairment (MCI)…
View article: An attentional and working memory theory of hallucination vulnerability in frontotemporal dementia
An attentional and working memory theory of hallucination vulnerability in frontotemporal dementia Open
The rate and prevalence of hallucinations in behavioural variant frontotemporal dementia is well established. The mechanisms for underlying vulnerability however are the least well described in FTD compared with other neuropsychiatric cond…