James T. Cassidy
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View article: Enhancing emergency front‐of‐neck airway training: a mixed methods study on the impact of external noise and startle stressors
Enhancing emergency front‐of‐neck airway training: a mixed methods study on the impact of external noise and startle stressors Open
Summary Introduction Our aim was to investigate whether emergency front‐of‐neck airway training utilising low‐fidelity manikins in a ‘tea‐trolley’ format could be improved by the incorporation of stress inoculation training. This would be …
View article: Data from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Data from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Open
Purpose: This randomized, double-blind, placebo-controlled, phase IIb study evaluated adding sorafenib to first-line modified FOLFOX6 (mFOLFOX6) for metastatic colorectal cancer (mCRC).Experimental Design: Patients were rando…
View article: Supplementary Table A3 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Supplementary Table A3 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Open
Study drug dosing
View article: Supplementary Table A1 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Supplementary Table A1 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Open
Progression-free survival (Kaplan-Meier Method) by PIK3CA and NRAS status
View article: Supplementary Table A1 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Supplementary Table A1 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Open
Progression-free survival (Kaplan-Meier Method) by PIK3CA and NRAS status
View article: Supplementary Appendix from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Supplementary Appendix from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Open
Supplementary Appendix
View article: Supplementary Table A3 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Supplementary Table A3 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Open
Study drug dosing
View article: Supplementary Appendix from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Supplementary Appendix from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Open
Supplementary Appendix
View article: Data from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Data from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Open
Purpose: This randomized, double-blind, placebo-controlled, phase IIb study evaluated adding sorafenib to first-line modified FOLFOX6 (mFOLFOX6) for metastatic colorectal cancer (mCRC).Experimental Design: Patients were rando…
View article: Supplementary Table A2 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Supplementary Table A2 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Open
Overall survival (Kaplan-Meier Method) by PIK3CA and NRAS status
View article: Supplementary Table A2 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Supplementary Table A2 from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial Open
Overall survival (Kaplan-Meier Method) by PIK3CA and NRAS status
View article: Data from Mechanistic and Predictive Profiling of 5-Fluorouracil Resistance in Human Cancer Cells
Data from Mechanistic and Predictive Profiling of 5-Fluorouracil Resistance in Human Cancer Cells Open
Gene expression was analyzed in five pairs of 5-fluorouracil (5-FU) resistant and parental cancer cell lines on DNA microarrays. In unsupervised analysis, a prediction rule was built from the expression profiles of 29 genes, and 5-FU sensi…
View article: Supplementary Table from Mechanistic and Predictive Profiling of 5-Fluorouracil Resistance in Human Cancer Cells
Supplementary Table from Mechanistic and Predictive Profiling of 5-Fluorouracil Resistance in Human Cancer Cells Open
Supplementary Table from Mechanistic and Predictive Profiling of 5-Fluorouracil Resistance in Human Cancer Cells
View article: Data from Mechanistic and Predictive Profiling of 5-Fluorouracil Resistance in Human Cancer Cells
Data from Mechanistic and Predictive Profiling of 5-Fluorouracil Resistance in Human Cancer Cells Open
Gene expression was analyzed in five pairs of 5-fluorouracil (5-FU) resistant and parental cancer cell lines on DNA microarrays. In unsupervised analysis, a prediction rule was built from the expression profiles of 29 genes, and 5-FU sensi…
View article: Supplementary Table from Mechanistic and Predictive Profiling of 5-Fluorouracil Resistance in Human Cancer Cells
Supplementary Table from Mechanistic and Predictive Profiling of 5-Fluorouracil Resistance in Human Cancer Cells Open
Supplementary Table from Mechanistic and Predictive Profiling of 5-Fluorouracil Resistance in Human Cancer Cells
View article: Head and neck positioning for out-of-theatre intubation during the COVID-19 pandemic
Head and neck positioning for out-of-theatre intubation during the COVID-19 pandemic Open
The COVID-19 pandemic has brought with it a large number of challenges for healthcare professionals including intubation safety in out-of-theatre environments. An important aspect of this topic is the optimisation of a patient’s head and n…
View article: The 'Short Course Oncology Treatment' (SCOT) trial
The 'Short Course Oncology Treatment' (SCOT) trial Open
6 months of oxaliplatin-containing chemotherapy is usually given as adjuvant treatment for stage 3 colorectal cancer. We investigated whether 3 months of oxaliplatin-containing chemotherapy would be non-inferior to the usual 6 months of tr…
View article: A pilot study of subjective well-being in colorectal cancer patients and their caregivers
A pilot study of subjective well-being in colorectal cancer patients and their caregivers Open
Caregivers are as anxious or depressed as patients, and report similar levels of life satisfaction but lower daily mood. A focus on SWB could provide a valid assessment of treatment benefit. Given the interesting results of this pilot stud…