James G. Wrightson
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View article: Defining and Characterizing Visits To Emergency Departments For Musculoskeletal Conditions: A Retrospective Analysis Using Two Publicly Available Databases
Defining and Characterizing Visits To Emergency Departments For Musculoskeletal Conditions: A Retrospective Analysis Using Two Publicly Available Databases Open
Background The number of people with musculoskeletal conditions who visit the ED is estimated to range from 3-25% of all ED visits, challenging health service planning. The aim of this study was to examine how using different ICD code list…
View article: GPT for RCTs? Using AI to determine adherence to clinical trial reporting guidelines
GPT for RCTs? Using AI to determine adherence to clinical trial reporting guidelines Open
Objectives Adherence to established reporting guidelines can improve clinical trial reporting standards, but attempts to improve adherence have produced mixed results. This exploratory study aimed to determine how accurate a large language…
View article: What factors are important to the success of resubmitted grant applications in biomedical and health research? A retrospective study of over 20 000 applications to the Canadian Institutes of Health Research
What factors are important to the success of resubmitted grant applications in biomedical and health research? A retrospective study of over 20 000 applications to the Canadian Institutes of Health Research Open
In this retrospective study, we investigated the outcomes (funded/not funded) and factors related to the funding of resubmitted applications to the Canadian Institutes of Health Research (CIHR) Open Operating Grants Competition and Project…
View article: Biomedical research grant resubmission: rates and factors related to success – a scoping review
Biomedical research grant resubmission: rates and factors related to success – a scoping review Open
Objectives Most first-time biomedical research grant applications are not funded. In the challenging research funding climate, resubmitting a grant application is a necessary task for scientists. Identifying which factors influence their d…
View article: “Best Paper” awards lack transparency, inclusivity, and support for Open Science
“Best Paper” awards lack transparency, inclusivity, and support for Open Science Open
Awards can propel academic careers. They also reflect the culture and values of the scientific community. But do awards incentivize greater transparency, inclusivity, and openness in science? Our cross-disciplinary survey of 222 awards for…
View article: What Factors are Important to the Success of Resubmitted Grant Applications in Health Research? A Retrospective Study of Over 20,000 Applications to the Canadian Institutes of Health Research
What Factors are Important to the Success of Resubmitted Grant Applications in Health Research? A Retrospective Study of Over 20,000 Applications to the Canadian Institutes of Health Research Open
Background In this retrospective study, we investigated the outcomes (funded/not funded) and factors related to the funding of resubmitted applications to the Canadian Institutes of Health Research (CIHR) Open Operating Grants Competition …
View article: Fatigue in children using motor imagery and P300 brain-computer interfaces
Fatigue in children using motor imagery and P300 brain-computer interfaces Open
Background Brain-computer interface (BCI) technology offers children with quadriplegic cerebral palsy unique opportunities for communication, environmental exploration, learning, and game play. Research in adults demonstrates a negative im…
View article: GPT for RCTs?: Using AI to determine adherence to reporting guidelines
GPT for RCTs?: Using AI to determine adherence to reporting guidelines Open
Background Adherence to established reporting guidelines can improve clinical trial reporting standards, but attempts to improve adherence have produced mixed results. This exploratory study aimed to determine how accurate a Large Language…
View article: Best Paper awards lack transparency, inclusivity, and support for Open Science
Best Paper awards lack transparency, inclusivity, and support for Open Science Open
Awards can propel academic careers. They also reflect the culture and values of the scientific community. But, do awards incentivise greater transparency, diversity, and openness in science? Our cross-disciplinary survey of 222 awards for …
View article: Fatigue in Children Using Motor Imagery and P300 Brain-Computer Interfaces
Fatigue in Children Using Motor Imagery and P300 Brain-Computer Interfaces Open
Background Brain-computer interface (BCI) technology offers children with quadriplegic cerebral palsy unique opportunities for communication, environmental exploration, learning, and game play. Research in adults demonstrates a negative im…
View article: Differences in neurometabolites and transcranial magnetic stimulation motor maps in children with attention-deficit/hyperactivity disorder
Differences in neurometabolites and transcranial magnetic stimulation motor maps in children with attention-deficit/hyperactivity disorder Open
Background: Although much is known about cognitive dysfunction in attention-deficit/hyperactivity disorder (ADHD), few studies have examined the pathophysiology of disordered motor circuitry. We explored differences in neurometabolite leve…
View article: Active versus resting neuro‐navigated robotic transcranial magnetic stimulation motor mapping
Active versus resting neuro‐navigated robotic transcranial magnetic stimulation motor mapping Open
Transcranial magnetic stimulation (TMS) motor mapping is a safe, non‐invasive method that can be used to study corticomotor organization. Motor maps are typically acquired at rest, and comparisons to maps obtained during muscle activation …
View article: Robotic mapping of motor cortex in children with perinatal stroke and hemiparesis
Robotic mapping of motor cortex in children with perinatal stroke and hemiparesis Open
Brain stimulation combined with intensive therapy may improve hand function in children with perinatal stroke‐induced unilateral cerebral palsy (UCP). However, response to therapy varies and underlying neuroplasticity mechanisms remain unc…
View article: Fatigue in perinatal stroke is associated with resting-state functional connectivity
Fatigue in perinatal stroke is associated with resting-state functional connectivity Open
Fatigue is prevalent in youth with perinatal stroke, but the causes are unclear. Predictive coding models of adult post-stroke fatigue suggest that fatigue may arise from dysfunction in predictive processing networks. To date, the associat…
View article: “I feel like my body is broken”: Exploring the experiences of people living with long COVID
“I feel like my body is broken”: Exploring the experiences of people living with long COVID Open
Background Long COVID, an illness affecting a subset of individuals after COVID-19, is distressing and poorly understood. Exploring the experiences of people with long COVID could help inform current conceptualizations of the illness, guid…
View article: Chronic Fatigue and Postexertional Malaise in People Living With Long COVID: An Observational Study
Chronic Fatigue and Postexertional Malaise in People Living With Long COVID: An Observational Study Open
Objective People living with long COVID describe a high symptom burden, and a more detailed assessment is needed to inform rehabilitation recommendations. The objectives were to use validated questionnaires to measure the severity of fatig…
View article: Effect of the subjective intensity of fatigue and interoception on perceptual regulation and performance during sustained physical activity
Effect of the subjective intensity of fatigue and interoception on perceptual regulation and performance during sustained physical activity Open
Background The subjective experience of fatigue impairs an individual’s ability to sustain physical endurance performance. However, precise understanding of the specific role perceived fatigue plays in the central regulation of performance…
View article: Physical Activity in Adults With Fatigue After Cancer Treatment
Physical Activity in Adults With Fatigue After Cancer Treatment Open
Physical activity is recommended for the management of cancer-related fatigue (CRF), yet the evidence is primarily based on interventions delivered during cancer treatment, with no eligibility criterion for fatigue. There is a need to exam…
View article: Effects of Transcranial Direct Current Stimulation and High-Definition Transcranial Direct Current Stimulation Enhanced Motor Learning on Robotic Transcranial Magnetic Stimulation Motor Maps in Children
Effects of Transcranial Direct Current Stimulation and High-Definition Transcranial Direct Current Stimulation Enhanced Motor Learning on Robotic Transcranial Magnetic Stimulation Motor Maps in Children Open
Introduction: Conventional transcranial direct current stimulation (tDCS) and high-definition tDCS (HD-tDCS) may improve motor learning in children. Mechanisms are not understood. Neuronavigated robotic transcranial magnetic stimulation (T…
View article: Prolonged cognitive activity increases perception of fatigue but does not influence perception of effort, affective valence, or performance during subsequent isometric endurance exercise.
Prolonged cognitive activity increases perception of fatigue but does not influence perception of effort, affective valence, or performance during subsequent isometric endurance exercise. Open
Performance of a cognitively demanding task has previously been reported to impair subsequent physical endurance performance, an effect attributed to sensory processes influencing the perceived effort required to maintain performance. Howe…
View article: Chronic fatigue and post-exertional malaise in people living with long COVID
Chronic fatigue and post-exertional malaise in people living with long COVID Open
Purpose People living with long COVID describe a high symptom burden, and a more detailed assessment of chronic fatigue and post-exertional malaise (PEM) may inform the development of rehabilitation recommendations. The aims of this study …