D. Klein
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View article: Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition
Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition Open
Outer membrane proteins (OMPs) produced by Gram-negative bacteria contain a cylindrical amphipathic β-sheet (“β-barrel”) that functions as a membrane spanning domain. The assembly (folding and membrane insertion) of OMPs is mediated by the…
View article: Active Learning in STEM Education with Regard to the Development of Inquiry Skills
Active Learning in STEM Education with Regard to the Development of Inquiry Skills Open
Active learning, represented by inquiry-based science education (IBSE) strategies, is considered essential for students to develop skills and knowledge to prepare for the challenges of the 21st century world. The success of IBSE, and the r…
View article: Severe Gastric Mucosal Necrosis Due to Giant Paraesophageal Hernia
Severe Gastric Mucosal Necrosis Due to Giant Paraesophageal Hernia Open
View article: Python vs. the pandemic: a case study in high-stakes software development
Python vs. the pandemic: a case study in high-stakes software development Open
When it became clear in early 2020 that COVID-19 was going to be a major public health threat, politicians and public health officials turned to academic disease modelers like us for urgent guidance. Academic software development is typica…
View article: Aprendendo sobre a Nutrição Balanceada com o Jogo Meal Match
Aprendendo sobre a Nutrição Balanceada com o Jogo Meal Match Open
O artigo tem como finalidade apresentar o desenvolvimento e a utilização do jogo Meal Match, um jogo casual desenvolvido para o uso em dispositivos móveis, como recurso no auxílio à conscientização e mobilização para uma nutrição saudável,…
View article: Evaluating maternal psychopathology biases in reports of child temperament: An investigation of measurement invariance
Evaluating maternal psychopathology biases in reports of child temperament: An investigation of measurement invariance Open
Parent, especially mothers’, reports of child temperament are frequently used in research and clinical practice, but there are concerns that maternal characteristics, including a history of psychopathology, may bias reports on these measur…
View article: Multiple domains of risk factors for first onset of depression in adolescent girls
Multiple domains of risk factors for first onset of depression in adolescent girls Open
Background: First onsets of depression are especially common in adolescent females and often develop into chronic/recurrent illness. Surprisingly few studies have comprehensively evaluated multiple domains of etiologically-informative risk…
View article: Computer Aided Internal Optimisation (CAIO) method for fibre trajectory optimisation: A deep dive to enhance applicability
Computer Aided Internal Optimisation (CAIO) method for fibre trajectory optimisation: A deep dive to enhance applicability Open
The computer aided internal optimisation (CAIO) method produces an optimised fibre layout for parts made from fibre-reinforced plastics (FRP), starting from an initial shell geometry and a given load case. Its main principle is iterative r…
View article: Profiles of Psychosocial and Clinical Functioning in Adolescence and Risk for Later Depression
Profiles of Psychosocial and Clinical Functioning in Adolescence and Risk for Later Depression Open
Background: Most studies examining predictors of onset of depression focus on variable centered regression methods that focus on effects of multiple predictors. In contrast, person-centered approaches develop profiles of factors and these …