David Grant
YOU?
Author Swipe
View article: Thermo-Fluid Modeling Framework for Supercomputer Digital Twins: Part 1, Demonstration at Exascale
Thermo-Fluid Modeling Framework for Supercomputer Digital Twins: Part 1, Demonstration at Exascale Open
A thermo-fluid modeling framework is being developed for ExaDigiT—an open-source framework for developing comprehensive digital twins of liquid-cooled supercomputers. The work is being conducted in two parts, and discussion is divided into…
View article: A Digital Twin Framework for Liquid-cooled Supercomputers as Demonstrated at Exascale
A Digital Twin Framework for Liquid-cooled Supercomputers as Demonstrated at Exascale Open
We present ExaDigiT, an open-source framework for developing comprehensive digital twins of liquid-cooled supercomputers. It integrates three main modules: (1) a resource allocator and power simulator, (2) a transient thermo-fluidic coolin…
View article: Evaluation of efficacy, outcomes and safety of infant haemodialysis and ultrafiltration in clinical use: I-KID a stepped wedge cluster RCT
Evaluation of efficacy, outcomes and safety of infant haemodialysis and ultrafiltration in clinical use: I-KID a stepped wedge cluster RCT Open
Background Critically unwell babies in intensive care units may develop acute renal failure. Options for renal replacement therapy are limited by their small size and available technology. Objectives To determine the clinical efficacy, out…
View article: Predictive value of the National Early Warning Score 2 for hospitalised patients with viral respiratory illness is improved by the addition of inspired oxygen fraction as a weighted variable
Predictive value of the National Early Warning Score 2 for hospitalised patients with viral respiratory illness is improved by the addition of inspired oxygen fraction as a weighted variable Open
Objectives The National Early Warning Score 2 (NEWS2) is validated for predicting acute deterioration, however, the binary grading of inspired oxygen fraction (FiO 2 ) may limit performance. We evaluated the incorporation of FiO 2 as a wei…
View article: Pulmonary Cystic Echinococcosis in a Child Presenting in the United Kingdom with Fever and Chest Pain: A Brief Report and Discussion on Management
Pulmonary Cystic Echinococcosis in a Child Presenting in the United Kingdom with Fever and Chest Pain: A Brief Report and Discussion on Management Open
Cystic echinococcosis is a zoonosis caused by the larvae of Echinococcus granulosus . Pulmonary disease may be asymptomatic until the cyst ruptures or becomes secondarily infected. We report a case of pulmonary cystic echinococcosis presen…
View article: The Infant KIdney Dialysis and Utrafiltration (I-KID) Study: A Stepped-Wedge Cluster-Randomized Study in Infants, Comparing Peritoneal Dialysis, Continuous Venovenous Hemofiltration, and Newcastle Infant Dialysis Ultrafiltration System, a Novel Infant Hemodialysis Device
The Infant KIdney Dialysis and Utrafiltration (I-KID) Study: A Stepped-Wedge Cluster-Randomized Study in Infants, Comparing Peritoneal Dialysis, Continuous Venovenous Hemofiltration, and Newcastle Infant Dialysis Ultrafiltration System, a Novel Infant Hemodialysis Device Open
Objectives: Renal replacement therapy (RRT) options are limited for small babies because of lack of available technology. We investigated the precision of ultrafiltration, biochemical clearances, clinical efficacy, outcomes, and safety pro…
View article: Deep2Lead: A distributed deep learning application for small molecule lead optimization
Deep2Lead: A distributed deep learning application for small molecule lead optimization Open
Lead optimization is a key step in drug discovery to produce potent and selective compounds. Historically, in silico screening and structure-based small molecule designing facilitated the processes. Although the recent application of deep …
View article: Deep2Lead: A distributed deep learning application for small molecule\n lead optimization
Deep2Lead: A distributed deep learning application for small molecule\n lead optimization Open
Lead optimization is a key step in drug discovery to produce potent and\nselective compounds. Historically, in silico screening and structure-based\nsmall molecule designing facilitated the processes. Although the recent\napplication of de…
View article: They don’t really care about us: the stories of previously Incarcerated black men in Scarborough and their experiences with displaced anger through a critical race theory perspective
They don’t really care about us: the stories of previously Incarcerated black men in Scarborough and their experiences with displaced anger through a critical race theory perspective Open
This narrative qualitative research study investigates aspects of the life journey of Black male adults in the urban context, Scarborough, Ontario through a Critical Race Theory (CRT) Perspective. Four Black male adults who lived in Scarbo…
The ROX index has greater predictive validity than NEWS2 for deterioration in Covid-19 Open
NEWS2 may under-perform in Covid-19 due to intrinsic limitations of the design and the unique pathophysiology of the disease. A simple index utilising respiratory parameters can outperform NEWS2 in predicting the occurrence of adverse even…
View article: Manifesto for healthcare simulation practice
Manifesto for healthcare simulation practice Open
A pandemic has sent the world into chaos. It has not only upended our lives; hundreds of thousands of lives have already been tragically lost. The global crisis has been disruptive, even a threat, to healthcare simulation, affecting all as…
View article: Simulation and Active Learning Decreases Training Time of an Emergency Triage Assessment and Treatment Course in Pilot Study in Malawi
Simulation and Active Learning Decreases Training Time of an Emergency Triage Assessment and Treatment Course in Pilot Study in Malawi Open
Objectives The aim of the Emergency Triage Assessment and Treatment (ETAT) plus trauma course is to improve the quality of care provided to infants and children younger than 5 years. The curriculum was revised and shortened from 5 to 2.5 d…
View article: Canadian Association of General Surgeons position statement: recommendations for surgeons with blood-borne communicable diseases
Canadian Association of General Surgeons position statement: recommendations for surgeons with blood-borne communicable diseases Open
The potential for transmission of hematogenously transmitted pathogens during exposure-prone procedures is a clinically important concern to both patients and surgeons. There is inconsistency among regulatory bodies in Canada regarding the…