James Lamb
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View article: Enhancing cyberattack resiliency through the radiotherapy backup and recovery dashboard tool
Enhancing cyberattack resiliency through the radiotherapy backup and recovery dashboard tool Open
Purpose Radiation Oncology departments impacted by recent cyberattacks were unable to access data backups or their Record and Verify (R&V) system and therefore faced challenges to resume patient treatments in a timely manner. We present a …
View article: High energy cosmic ray detections with the standalone radio trigger system at the Owens Valley Radio Observatory Long Wavelength Array
High energy cosmic ray detections with the standalone radio trigger system at the Owens Valley Radio Observatory Long Wavelength Array Open
View article: Measuring the Magnetic Field of a Coronal Mass Ejection from the Low to Middle Corona
Measuring the Magnetic Field of a Coronal Mass Ejection from the Low to Middle Corona Open
A major challenge in understanding the initiation and evolution of coronal mass ejections (CMEs) is measuring the magnetic field of the magnetic flux ropes (MFRs) that drive CMEs. Recent developments in radio imaging spectroscopy have pave…
View article: MR-Guided Radiation Therapy for Prostate and Pancreas Cancer Treatment: A Dosimetric Study Across Two Major MR-Linac Platforms
MR-Guided Radiation Therapy for Prostate and Pancreas Cancer Treatment: A Dosimetric Study Across Two Major MR-Linac Platforms Open
Background/Objectives: MR-guided radiation therapy (MRgRT) has rapidly evolved into an important treatment modality, with the Elekta Unity and ViewRay MRIdian systems being two major MR-linac platforms. Despite the shared concept of MRgRT,…
View article: Accessory secondary plaque in brachytherapy for uveal melanoma
Accessory secondary plaque in brachytherapy for uveal melanoma Open
An accessory brachytherapy plaque is a practical solution to manage unexpected deficiencies in plaque coverage of the primary melanoma which avoids treatment delay and minimizes time for potential tumor growth. It may also avoid suboptimal…
View article: A clustering‐based approach to address correlated features in predicting genitourinary toxicity from MRI‐guided prostate SBRT
A clustering‐based approach to address correlated features in predicting genitourinary toxicity from MRI‐guided prostate SBRT Open
Background It is common in outcome analysis to work with a large set of candidate prognostic features. However, such high‐dimensional input and relatively small sample size leads to risk of overfitting, low generalizability, and correlatio…
View article: Open‐source deep‐learning models for segmentation of normal structures for prostatic and gynecological high‐dose‐rate brachytherapy: Comparison of architectures
Open‐source deep‐learning models for segmentation of normal structures for prostatic and gynecological high‐dose‐rate brachytherapy: Comparison of architectures Open
Background The use of deep learning‐based auto‐contouring algorithms in various treatment planning services is increasingly common. There is a notable deficit of commercially or publicly available models trained on large or diverse dataset…
View article: A generalized software framework for consolidation of radiotherapy planning and delivery data from diverse data sources
A generalized software framework for consolidation of radiotherapy planning and delivery data from diverse data sources Open
Aggregating large-scale radiotherapy planning and delivery data is crucial for advancing radiation oncology research and improving clinical practice, yet challenges persist due to the diversity of treatment planning systems (TPS), record a…
View article: Magnetic Resonance Imaging Versus Computed Tomography Guidance for Stereotactic Body Radiotherapy in Prostate Cancer: 2-year Outcomes from the MIRAGE Randomized Clinical Trial
Magnetic Resonance Imaging Versus Computed Tomography Guidance for Stereotactic Body Radiotherapy in Prostate Cancer: 2-year Outcomes from the MIRAGE Randomized Clinical Trial Open
It has been shown that magnetic resonance imaging (MRI) guidance versus computed tomography (CT) guidance for aggressive margin-reduction (AMR) for stereotactic body radiotherapy (SBRT) in prostate cancer reduces acute toxicity, but the lo…
View article: Preferential Occurrence of Fast Radio Bursts in Massive Star-Forming Galaxies
Preferential Occurrence of Fast Radio Bursts in Massive Star-Forming Galaxies Open
Fast Radio Bursts (FRBs) are millisecond-duration events detected from beyond the Milky Way. FRB emission characteristics favor highly magnetized neutron stars, or magnetars, as the sources, as evidenced by FRB-like bursts from a galactic …
View article: Clinical physicists’ perceptions of weekly chart checks and the potential role for automated image review assessed by structured interviews
Clinical physicists’ perceptions of weekly chart checks and the potential role for automated image review assessed by structured interviews Open
Background This study utilizes interviews of clinical medical physicists to investigate self‐reported shortcomings of the current weekly chart check workflow and opportunities for improvement. Methods Nineteen medical physicists were recru…
View article: Automated detection of vertebral body misalignments in orthogonal kV and MV guided radiotherapy: application to a comprehensive retrospective dataset
Automated detection of vertebral body misalignments in orthogonal kV and MV guided radiotherapy: application to a comprehensive retrospective dataset Open
Objective . In image-guided radiotherapy (IGRT), off-by-one vertebral body misalignments are rare but potentially catastrophic. In this study, a novel detection method for such misalignments in IGRT was investigated using densely-connected…
View article: (016) Sexual Health Toxicity Following MRI-Guided versus CT-guided Prostate SBRT
(016) Sexual Health Toxicity Following MRI-Guided versus CT-guided Prostate SBRT Open
Introduction Sexual health toxicities remain an under-reported but important health outcome for patients undergoing radiotherapy for localized prostate cancer. With the increasing adoption of higher daily doses of radiation over shorter ti…
View article: One Year Radiographic Response Following Prostrate SBRT: An Exploratory Analysis of a Phase III Randomized Trial
One Year Radiographic Response Following Prostrate SBRT: An Exploratory Analysis of a Phase III Randomized Trial Open
View article: MRI-Guided Radiation Therapy for Prostate Cancer: The Next Frontier in Ultrahypofractionation
MRI-Guided Radiation Therapy for Prostate Cancer: The Next Frontier in Ultrahypofractionation Open
Technological advances in MRI-guided radiation therapy (MRIgRT) have improved real-time visualization of the prostate and its surrounding structures over CT-guided radiation therapy. Seminal studies have demonstrated safe dose escalation a…
View article: Proof‐of‐concept study of artificial intelligence‐assisted review of CBCT image guidance
Proof‐of‐concept study of artificial intelligence‐assisted review of CBCT image guidance Open
Purpose Automation and computer assistance can support quality assurance tasks in radiotherapy. Retrospective image review requires significant human resources, and automation of image review remains a noteworthy missing element in previou…
View article: Air All in the Wrong Places: A Case of Pneumorrhachis Secondary to Chronic Vomiting
Air All in the Wrong Places: A Case of Pneumorrhachis Secondary to Chronic Vomiting Open
Pneumorrhachis (PR) is a rare phenomenon in which air is present in the spinal canal. PR can be stratified into different categories based on etiology, with spontaneous PR being the least common. In this report, we describe the case of a 3…
View article: Magnetic Resonance Imaging–Guided vs Computed Tomography–Guided Stereotactic Body Radiotherapy for Prostate Cancer
Magnetic Resonance Imaging–Guided vs Computed Tomography–Guided Stereotactic Body Radiotherapy for Prostate Cancer Open
Importance Magnetic resonance imaging (MRI) guidance offers multiple theoretical advantages in the context of stereotactic body radiotherapy (SBRT) for prostate cancer. However, to our knowledge, these advantages have yet to be demonstrate…
View article: Feasibility of a deep-learning based anatomical region labeling tool for Cone-Beam Computed Tomography scans in radiotherapy
Feasibility of a deep-learning based anatomical region labeling tool for Cone-Beam Computed Tomography scans in radiotherapy Open
The high classification accuracy demonstrated by ARL suggests that it may be employed as a pre-processing step for site-specific, CBCT-based radiotherapy tools.
View article: Anti-contactin associated protein like 2 autoimmune encephalitis: A case report and review of the literature
Anti-contactin associated protein like 2 autoimmune encephalitis: A case report and review of the literature Open
Autoimmune encephalitis is an insidious neurological disease that can present with an array of neuropsychiatric symptoms. Further classification of autoimmune encephalitis is determined by the presence of unique antibodies such as anti-con…
View article: Dosimetric evaluation of respiratory gating on a 0.35‐T magnetic resonance–guided radiotherapy linac
Dosimetric evaluation of respiratory gating on a 0.35‐T magnetic resonance–guided radiotherapy linac Open
Purpose The commercial 0.35‐T magnetic resonance imaging (MRI)‐guided radiotherapy vendor ViewRay recently introduced upgraded real‐time imaging frame rates based on compressed sensing techniques. Furthermore, additional motion tracking al…
View article: Barriers and facilitators to clinical implementation of radiotherapy treatment planning automation: A survey study of medical dosimetrists
Barriers and facilitators to clinical implementation of radiotherapy treatment planning automation: A survey study of medical dosimetrists Open
Purpose Little is known about the scale of clinical implementation of automated treatment planning techniques in the United States. In this work, we examine the barriers and facilitators to adoption of commercially available automated plan…
View article: Offline generator for digitally reconstructed radiographs of a commercial stereoscopic radiotherapy image‐guidance system
Offline generator for digitally reconstructed radiographs of a commercial stereoscopic radiotherapy image‐guidance system Open
Purpose Image‐guided radiotherapy (IGRT) research sometimes involves simulated changes to patient positioning using retrospectively collected clinical data. For example, researchers may simulate patient misalignments to develop error detec…
View article: Machine‐assisted interpolation algorithm for semi‐automated segmentation of highly deformable organs
Machine‐assisted interpolation algorithm for semi‐automated segmentation of highly deformable organs Open
Purpose Accurate and robust auto‐segmentation of highly deformable organs (HDOs), for example, stomach or bowel, remains an outstanding problem due to these organs’ frequent and large anatomical variations. Yet, time‐consuming manual segme…
View article: Time-Driven Activity-Based Costing of CT-Guided vs MR-Guided Prostate SBRT
Time-Driven Activity-Based Costing of CT-Guided vs MR-Guided Prostate SBRT Open
This study provides an approximate comparison of the direct resources required for a radiation oncology provider to deliver prostate SBRT with CTgRT vs MRgRT. We await findings from the currently accruing phase III MIRAGE trial, which is c…
View article: Clinical outcomes of stereotactic magnetic resonance image‐guided adaptive radiotherapy for primary and metastatic tumors in the abdomen and pelvis
Clinical outcomes of stereotactic magnetic resonance image‐guided adaptive radiotherapy for primary and metastatic tumors in the abdomen and pelvis Open
Purpose Stereotactic body radiotherapy (SBRT) delivers ablative doses with excellent local control. However, implementing SBRT for abdominal and pelvic tumors has been limited by the risk for treatment‐related gastrointestinal toxicity. MR…
View article: Clinical assessment of geometric distortion for a 0.35T MR‐guided radiotherapy system
Clinical assessment of geometric distortion for a 0.35T MR‐guided radiotherapy system Open
Purpose To estimate the overall spatial distortion on clinical patient images for a 0.35 T MR‐guided radiotherapy system. Methods Ten patients with head‐and‐neck cancer underwent CT and MR simulations with identical immobilization. The MR …
View article: Magnetic resonance imaging-guided stereotactic body radiotherapy for prostate cancer (mirage): a phase iii randomized trial
Magnetic resonance imaging-guided stereotactic body radiotherapy for prostate cancer (mirage): a phase iii randomized trial Open
View article: Dosimetric Quality of Online Adapted Pancreatic Cancer Treatment Plans on an MRI-Guided Radiation Therapy System
Dosimetric Quality of Online Adapted Pancreatic Cancer Treatment Plans on an MRI-Guided Radiation Therapy System Open
View article: The Timeliness Initiative: Continuous Process Improvement for Prompt Initiation of Radiation Therapy Treatment
The Timeliness Initiative: Continuous Process Improvement for Prompt Initiation of Radiation Therapy Treatment Open