James Loughman
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View article: MyopiaX-1 Safety and Efficacy of a Novel Approach to Slow Juvenile Myopia Progression: A Multicenter, Randomized, Controlled Trial
MyopiaX-1 Safety and Efficacy of a Novel Approach to Slow Juvenile Myopia Progression: A Multicenter, Randomized, Controlled Trial Open
View article: IMI—Interventions for Controlling Myopia Onset and Progression 2025
IMI—Interventions for Controlling Myopia Onset and Progression 2025 Open
Myopia is recognized as a significant public health problem, particularly in East and Southeast Asia. This has led to the development and evaluation of a range of interventions to slow its progression and delay its onset. Since the publica…
View article: IMI—Instrumentation for Myopia Management
IMI—Instrumentation for Myopia Management Open
The rising prevalence of myopia has underscored the importance of early diagnosis and effective management strategies to control its progression and to prevent complications. Advancements in instrumentation enable clinicians to provide ind…
View article: Clinical Nomogram for Determining Expected Choroidal Thickness in Children With Myopia
Clinical Nomogram for Determining Expected Choroidal Thickness in Children With Myopia Open
View article: Optimising non‐cycloplegic screening strategies for early detection of pre‐myopia and myopia in young children
Optimising non‐cycloplegic screening strategies for early detection of pre‐myopia and myopia in young children Open
Purpose Early detection of myopia is essential to delay its onset and progression. Pre‐myopia, defined by an inadequate hyperopic reserve, increases myopia risk in childhood. However, effective screening methods remain limited. This study …
View article: Refractive Error and Axial Length (REAL) Study: Feasibility of a population study in the United States
Refractive Error and Axial Length (REAL) Study: Feasibility of a population study in the United States Open
SIGNIFICANCE: Myopia is the most common eye disease and a leading cause of blindness. A contemporary, large, and ethnically and geographically diverse study of ocular biometry and refractive error in children in the United States is needed…
View article: Erratum to: Raman Spectroscopic Analysis of Human Blood Serum of Glaucoma Patients Supplemented With Macular Pigment Carotenoids
Erratum to: Raman Spectroscopic Analysis of Human Blood Serum of Glaucoma Patients Supplemented With Macular Pigment Carotenoids Open
View article: TALK 1 Macular pigment optical volume is influenced by dietary intake and breastfeeding duration in Irish children
TALK 1 Macular pigment optical volume is influenced by dietary intake and breastfeeding duration in Irish children Open
View article: Patterns of Myopia Progression in European Adults
Patterns of Myopia Progression in European Adults Open
View article: Two‐year changes of macular choroidal thickness in response to 0.01% atropine eye drops: Results from the myopia outcome study of atropine in children ( <scp>MOSAIC</scp> ) clinical trial
Two‐year changes of macular choroidal thickness in response to 0.01% atropine eye drops: Results from the myopia outcome study of atropine in children ( <span>MOSAIC</span> ) clinical trial Open
Purpose To investigate 2‐year changes in macular choroidal thickness (ChT) in children receiving 0.01% atropine eyedrops and its relationship with spherical equivalent refraction (SER) progression and axial length (AL) elongation. Methods …
View article: 2024 <scp>UK</scp> and Ireland modified Delphi consensus on myopia management in children and young people
2024 <span>UK</span> and Ireland modified Delphi consensus on myopia management in children and young people Open
Introduction This work aimed to establish the largest UK and Ireland consensus on myopia management in children and young people (CYP). Methods A modified Delphi consensus was conducted with a panel of 34 optometrists and ophthalmologists …
View article: Correction: The long and short of it: a comprehensive assessment of axial length estimation in myopic eyes from ocular and demographic variables
Correction: The long and short of it: a comprehensive assessment of axial length estimation in myopic eyes from ocular and demographic variables Open
View article: Raman spectroscopic analysis of human blood serum of glaucoma patients supplemented with macular pigment carotenoids
Raman spectroscopic analysis of human blood serum of glaucoma patients supplemented with macular pigment carotenoids Open
As all major dietary carotenoids are contained in blood, it is a suitable substrate to evaluate their content, in vivo. Following 18‐month supplementation of open‐angle glaucoma patients with macula‐pigment carotenoids (Lutein, Zeaxanthin …
View article: The long and short of it: a comprehensive assessment of axial length estimation in myopic eyes from ocular and demographic variables
The long and short of it: a comprehensive assessment of axial length estimation in myopic eyes from ocular and demographic variables Open
View article: Myopia progression patterns among paediatric patients in a clinical setting
Myopia progression patterns among paediatric patients in a clinical setting Open
Purpose This retrospective analysis of electronic medical record (EMR) data investigated the natural history of myopic progression in children from optometric practices in Ireland. Methods The analysis was of myopic patients aged 7–17 with…
View article: Short‐term effects of cyclopentolate and tropicamide eye drops on macular choroidal thickness in myopic children
Short‐term effects of cyclopentolate and tropicamide eye drops on macular choroidal thickness in myopic children Open
Background To investigate the short‐term effects of cyclopentolate and tropicamide eyedrops on choroidal thickness (ChT) in myopic children using placebo or low‐dose atropine eyedrops. Methods The analysis included 242 myopic individuals (…
View article: Myopia outcome study of atropine in children: Two‐year result of daily 0.01% atropine in a European population
Myopia outcome study of atropine in children: Two‐year result of daily 0.01% atropine in a European population Open
Purpose The Myopia Outcome Study of Atropine in Children (MOSAIC) is an investigator‐led, double‐masked, randomized controlled trial investigating the efficacy and safety of 0.01% atropine eye drops for managing myopia progression in a pre…
View article: Efficacy and Safety of 0.01% and 0.02% Atropine for the Treatment of Pediatric Myopia Progression Over 3 Years
Efficacy and Safety of 0.01% and 0.02% Atropine for the Treatment of Pediatric Myopia Progression Over 3 Years Open
Importance The global prevalence of myopia is predicted to approach 50% by 2050, increasing the risk of visual impairment later in life. No pharmacologic therapy is approved for treating childhood myopia progression. Objective To assess th…
View article: Prescribing patterns of myopia control contact lenses among optometrists in Ireland
Prescribing patterns of myopia control contact lenses among optometrists in Ireland Open
Purpose This retrospective analysis of electronic medical record (EMR) data investigated the prescribing patterns of soft myopia control contact lens (MCCL) treatments since their introduction in Ireland in 2017. Methods Anonymised EMR dat…
View article: Raman Spectroscopy of Carotenoid Compounds for Clinical Applications—A Review
Raman Spectroscopy of Carotenoid Compounds for Clinical Applications—A Review Open
Carotenoid compounds are ubiquitous in nature, providing the characteristic colouring of many algae, bacteria, fruits and vegetables. They are a critical component of the human diet and play a key role in human nutrition, health and diseas…
View article: Low‐concentration atropine eyedrops for myopia control in a multi‐racial cohort of Australian children: A randomised clinical trial
Low‐concentration atropine eyedrops for myopia control in a multi‐racial cohort of Australian children: A randomised clinical trial Open
Background To test the hypothesis that 0.01% atropine eyedrops are a safe and effective myopia‐control approach in Australian children. Methods Children (6–16 years; 49% Europeans, 18% East Asian, 22% South Asian, and 12% other/mixed ances…
View article: Regional variations and temporal trends of childhood myopia prevalence in Africa: A systematic review and meta‐analysis
Regional variations and temporal trends of childhood myopia prevalence in Africa: A systematic review and meta‐analysis Open
Purpose To provide contemporary and future estimates of childhood myopia prevalence in Africa. Methods A systematic online literature search was conducted for articles on childhood (≤18 years) myopia (spherical equivalent [SE] ≤ −0.50D; hi…
View article: Quantitative Raman Analysis of Carotenoid Protein Complexes in Aqueous Solution
Quantitative Raman Analysis of Carotenoid Protein Complexes in Aqueous Solution Open
Carotenoids are naturally abundant, fat-soluble pigmented compounds with dietary, antioxidant and vision protection advantages. The dietary carotenoids, Beta Carotene, Lutein, and Zeaxanthin, complexed with in bovine serum albumin (BSA) in…
View article: Will treating progressive myopia overwhelm the eye care workforce? A workforce modelling study
Will treating progressive myopia overwhelm the eye care workforce? A workforce modelling study Open
Purpose Treatments for myopia progression are now available, but implementing these into clinical practice will place a burden on the eye care workforce. This study estimated the full‐time equivalent (FTE) workforce required to implement m…
View article: Big Data Analysis of Vision Screening Standards Used to Evaluate Fitness to Drive
Big Data Analysis of Vision Screening Standards Used to Evaluate Fitness to Drive Open
Visual acuity (VA) assessment is the most commonly performed vision screening method for drivers. The standards and repeat assessment intervals used, however, are arbitrary, lack an evidence base and are highly variable across different co…
View article: Big Data Analysis of Vision Screening Standards Used to Evaluate Fitness to Drive
Big Data Analysis of Vision Screening Standards Used to Evaluate Fitness to Drive Open
Visual acuity (VA) assessment is the most commonly performed vision screening method for drivers. The standards and repeat assessment intervals used, however, are arbitrary, lack an evidence base and are highly variable across different co…
View article: Using electronic medical record data to establish and monitor the distribution of refractive errors,
Using electronic medical record data to establish and monitor the distribution of refractive errors, Open
View article: The Refractive Error and Vision Impairment Estimation with Spectacle Data Study
The Refractive Error and Vision Impairment Estimation with Spectacle Data Study Open
The distribution of refractive error and hence the risk of vision impairment resulting from refractive error within a population can be determined using spectacle lens sales data. Pooling this type of data from multiple industry sources co…
View article: Macular Pigment Response to Lutein, Zeaxanthin, and Meso-zeaxanthin Supplementation in Open-Angle Glaucoma
Macular Pigment Response to Lutein, Zeaxanthin, and Meso-zeaxanthin Supplementation in Open-Angle Glaucoma Open
View article: The Refractive Error and Vision Impairment Estimation With Spectacle data (REVIEWS) study
The Refractive Error and Vision Impairment Estimation With Spectacle data (REVIEWS) study Open
Objective To investigate whether spectacle lens sales data can be used to estimate the population distribution of refractive error amongst ametropes and hence estimate the current and future risk of vision impairment. Design Cross Sectiona…