Kevin R. Ward
YOU?
Author Swipe
View article: Therapeutic Potentials of the Seaweed-Derived Compounds for Alzheimer’s Disease
Therapeutic Potentials of the Seaweed-Derived Compounds for Alzheimer’s Disease Open
Cognitive decline associated with healthy ageing and pathological conditions is driven by multifactorial processes, including oxidative stress, mitochondrial dysfunction and chronic neuroinflammation. Alzheimer’s Disease (AD), a progressiv…
View article: Future neutron capabilities at the National Physical Laboratory
Future neutron capabilities at the National Physical Laboratory Open
The National Physical Laboratory has provided industry and academia with fluence, energy, and dose standard neutron fields for characterising neutron detecting instruments since the 1960’s. Sectors such as civil nuclear power, defence, rad…
View article: Acute Care of Patients with Moderate Respiratory Distress: Recommendations from an American College of Emergency Physicians Expert Panel
Acute Care of Patients with Moderate Respiratory Distress: Recommendations from an American College of Emergency Physicians Expert Panel Open
Introduction: Patients with respiratory distress are frequently encountered in the emergency department (ED). Efforts to assess, initiate treatments, and stabilize these patients require a systematic and rapid response. Emergency physician…
View article: Factors associated with concussion during combatives activities in a military training environment
Factors associated with concussion during combatives activities in a military training environment Open
Females, higher BSI and BESS total scores at baseline, and participants with a history of headaches had greater odds of sustaining a combatives-related concussion during the follow-up period. Conversely, participants in high contact varsit…
View article: Fermentation of Microalgae as a Platform for Naturally Encapsulated Oil Powders: Characterization of a High-Oleic Algal Powder Ingredient
Fermentation of Microalgae as a Platform for Naturally Encapsulated Oil Powders: Characterization of a High-Oleic Algal Powder Ingredient Open
Powdered oil ingredients are widely used across food, nutrition, and personal care industries, but they are typically produced through encapsulation technologies that involve multiple additives and stabilizers. These systems can compromise…
View article: Improved outcomes with robotic-assisted laparoscopic paraesophageal hernia repairs compared with laparoscopic and transthoracic approaches: A single high-volume institution experience
Improved outcomes with robotic-assisted laparoscopic paraesophageal hernia repairs compared with laparoscopic and transthoracic approaches: A single high-volume institution experience Open
Robotic paraesophageal hernia repairs had generally lower 2-year recurrence and reoperation than lap and shorter hospital stays and fewer immediate complications than transthoracic.
View article: Charcot-Marie-Tooth disease type 1E: Clinical Natural History and Molecular Impact of<i>PMP22</i>Variants
Charcot-Marie-Tooth disease type 1E: Clinical Natural History and Molecular Impact of<i>PMP22</i>Variants Open
Charcot-Marie-Tooth disease type 1E (CMT1E) is a rare, autosomal dominant peripheral neuropathy caused by missense variants, deletions, and truncations within the peripheral myelin protein-22 ( PMP22 ) gene. CMT1E phenotypes vary depending…
View article: Endoscopic trans-gastric drainage of a peri-splenic abscess after laparoscopic appendectomy for perforated appendicitis: a case report
Endoscopic trans-gastric drainage of a peri-splenic abscess after laparoscopic appendectomy for perforated appendicitis: a case report Open
View article: Development and Production of High-Oleic Palm Oil Alternative by Fermentation of Microalgae
Development and Production of High-Oleic Palm Oil Alternative by Fermentation of Microalgae Open
The development of high-oleic palm oil alternatives through microbial fermentation offers a sustainable solution to the environmental challenges associated with traditional palm oil cultivation. In this study, a Prototheca moriformis micro…
View article: Extended endocrine therapy use and decision making after breast cancer diagnosis
Extended endocrine therapy use and decision making after breast cancer diagnosis Open
Background Adjuvant endocrine therapy is recommended to extend beyond 5 years for stage II breast cancer, with less consensus for extension in stage I. We aimed to understand use of and decision making about extended endocrine therapy. Met…
View article: 21 Optimizing AI-physician collaboration for enhanced diagnostic accuracy: A case study on acute respiratory distress syndrome detection using chest X-ray imaging
21 Optimizing AI-physician collaboration for enhanced diagnostic accuracy: A case study on acute respiratory distress syndrome detection using chest X-ray imaging Open
Objectives/Goals: The objective of this study is to explore strategies for AI-physician collaboration in diagnosing acute respiratory distress syndrome (ARDS) using chest X-rays. By comparing the diagnostic accuracy of different AI deploym…
View article: The Intersection of the Upper Gastrointestinal Microbiome and Oesophageal Cancer: A Review of Pathways and Therapeutic Insights
The Intersection of the Upper Gastrointestinal Microbiome and Oesophageal Cancer: A Review of Pathways and Therapeutic Insights Open
The upper gastrointestinal microbiome, a complex ecosystem of microorganisms that have historically been difficult to identify, may play a pivotal role in the development of oesophageal cancer and postoperative outcomes. Dysbiosis, charact…
View article: The Genetic Information and Family Testing (GIFT) study: trial design and protocol
The Genetic Information and Family Testing (GIFT) study: trial design and protocol Open
View article: Development and Production of High-Oleic Palm Oil Alternative by Fermentation of Microalgae
Development and Production of High-Oleic Palm Oil Alternative by Fermentation of Microalgae Open
The development of high-oleic palm oil alternatives through microbial fermentation offers a sustainable solution to the environmental challenges associated with traditional palm oil cultivation. In this study, Prototheca moriformis microal…
View article: Disease Progression in Charcot‐Marie‐Tooth Disease Type <scp>4B</scp> (<scp>CMT4B</scp>) Associated With Mutations in Myotubularin‐Related Proteins 2 and 13
Disease Progression in Charcot‐Marie‐Tooth Disease Type <span>4B</span> (<span>CMT4B</span>) Associated With Mutations in Myotubularin‐Related Proteins 2 and 13 Open
Background and Aims In 2019, we conducted a cross‐sectional study, collecting information on 50 patients with CMT4B, an ultrarare CMT subtype, to better define the clinical phenotype. We now aimed at investigating disease progression in 26…
View article: Epiploic Appendagitis in a Young Adult Female: A Rare Cause of Acute Abdominal Pain
Epiploic Appendagitis in a Young Adult Female: A Rare Cause of Acute Abdominal Pain Open
Epiploic appendagitis (EA) is an uncommon and frequently misdiagnosed cause of acute abdominal pain, typically affecting middle-aged males. This case report presents an atypical occurrence in a 32-year-old Hispanic female who presented wit…
View article: Development and Large-Scale Production of High-Oleic Acid Oil by Fermentation of Microalgae
Development and Large-Scale Production of High-Oleic Acid Oil by Fermentation of Microalgae Open
Our classical strain improvement began with an isolate showing 28% palmitic and 60% oleic acids. UV and chemical mutagenesis enhanced our strain’s productivity, carbon yield, and oleic acid content. The iterative methodology we used involv…
View article: Use of a continuous single lead electrocardiogram analytic to predict patient deterioration requiring rapid response team activation
Use of a continuous single lead electrocardiogram analytic to predict patient deterioration requiring rapid response team activation Open
Identifying the onset of patient deterioration is challenging despite the potential to respond to patients earlier with better vital sign monitoring and rapid response team (RRT) activation. In this study an ECG based software as a medical…
View article: Multiple bilateral paratubal cysts and recurrent bilateral fallopian tube torsion in a premenarchal female: A case report
Multiple bilateral paratubal cysts and recurrent bilateral fallopian tube torsion in a premenarchal female: A case report Open
Introduction: Paratubal cysts are rare cystic structures that are usually asymptomatic; rarely, they may cause torsion of the adnexa. Case presentation: We report the case of a 13-year-old premenarchal female who presented with left lower …
View article: Surgical Site Infection Bundle for Babies – Preliminary Data
Surgical Site Infection Bundle for Babies – Preliminary Data Open
Introduction & Background : Perioperative care bundles reduce surgical site infections (SSIs) in adults but are not used regularly in infant surgery. Infections in babies after surgery are less common but carry significant morbidity in a f…
View article: Use of a Continuous Single Lead Electrocardiogram Analytic to Predict Patient Deterioration Requiring Rapid Response Team Activation
Use of a Continuous Single Lead Electrocardiogram Analytic to Predict Patient Deterioration Requiring Rapid Response Team Activation Open
Identifying the onset of patient deterioration is challenging despite the potential to respond to patients earlier with better vital sign monitoring and rapid response team (RRT) activation. In this study an ECG based software as a medical…
View article: Transitioning From Points-Based Grading to a Modified Pass/Fail Grading Approach in a Simulated Patient Program
Transitioning From Points-Based Grading to a Modified Pass/Fail Grading Approach in a Simulated Patient Program Open
Our program was able to successfully move to a pass/fail approach for communication assessments of SP activities while maintaining points-based grading for clinical assessments in our P1 curriculum with minimal impact on student performanc…
View article: A Practical Approach to Disease Risk Prediction: Focus on High-Risk Patients via Highest-k Loss
A Practical Approach to Disease Risk Prediction: Focus on High-Risk Patients via Highest-k Loss Open
Disease risk prediction models play an important role in preventing disease developments in modern healthcare. However, the lack of focus on high-risk patients has hindered the large-scale practical application of these models, especially …
View article: Blood failure: traumatic hemorrhage and the interconnections between oxygen debt, endotheliopathy, and coagulopathy
Blood failure: traumatic hemorrhage and the interconnections between oxygen debt, endotheliopathy, and coagulopathy Open
This review explores the concept of “blood failure” in traumatic injury, which arises from the interplay of oxygen debt, the endotheliopathy of trauma (EoT), and acute traumatic coagulopathy (ATC). Traumatic hemorrhage leads to the accumul…
View article: Percutaneous left ventricular assist devices in refractory cardiac arrest: The role of chest compressions
Percutaneous left ventricular assist devices in refractory cardiac arrest: The role of chest compressions Open
The addition of mechanical chest compressions to percutaneous left ventricular assist device support during cardiac arrest may generate higher percutaneous left ventricular assist device and carotid artery flow prior to return of spontaneo…
View article: Prediction of episode of hemodynamic instability using an electrocardiogram based analytic: a retrospective cohort study
Prediction of episode of hemodynamic instability using an electrocardiogram based analytic: a retrospective cohort study Open
View article: Transcranial Color-Coded Sonography With Angle Correction As a Screening Tool for Raised Intracranial Pressure
Transcranial Color-Coded Sonography With Angle Correction As a Screening Tool for Raised Intracranial Pressure Open
OBJECTIVES: Transcranial Doppler (TCD) has been evaluated as a noninvasive intracranial pressure (ICP) assessment tool. Correction for insonation angle, a potential source of error, with transcranial color-coded sonography (TCCS) has not p…
View article: Effect of percutaneous ventricular assisted device on post-cardiac arrest myocardial dysfunction in swine model with prolonged cardiac arrest
Effect of percutaneous ventricular assisted device on post-cardiac arrest myocardial dysfunction in swine model with prolonged cardiac arrest Open
Background Percutaneous left ventricular assist device (pLVAD) can provide hemodynamic support during and after cardiac arrest, but it remains unclear if pLVAD reduces post-cardiac arrest myocardial dysfunction. Methods This is an analysis…
View article: Prediction of Episode of Hemodynamic Instability Using an Electrocardiogram Based Analytic: A Retrospective Cohort Study
Prediction of Episode of Hemodynamic Instability Using an Electrocardiogram Based Analytic: A Retrospective Cohort Study Open
Background Predicting the onset of hemodynamic instability before it occurs remains a sought-after goal in acute and critical care medicine. Technologies that allow for this may assist clinicians in preventing episodes of hemodynamic insta…
View article: Prediction of Episode of Hemodynamic Instability Using an Electrocardiogram Based Analytic: A Retrospective Cohort Study
Prediction of Episode of Hemodynamic Instability Using an Electrocardiogram Based Analytic: A Retrospective Cohort Study Open
Background Predicting the onset of hemodynamic instability before it occurs remains a sought-after goal in acute and critical care medicine. Technologies that allow for this may assist clinicians in preventing episodes of hemodynamic insta…