Stephen J. Palmer
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View article: Getting Physical: Providing a Physical Basis for Economic Growth Analyses to Fill the Information Gaps in Contemporary Economics for Policy Development for a Sustainable Global Economy
Getting Physical: Providing a Physical Basis for Economic Growth Analyses to Fill the Information Gaps in Contemporary Economics for Policy Development for a Sustainable Global Economy Open
View article: Data from A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells
Data from A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells Open
The actin cytoskeleton is a potentially vulnerable property of cancer cells, yet chemotherapeutic targeting attempts have been hampered by unacceptable toxicity. In this study, we have shown that it is possible to disrupt specific actin fi…
View article: Supplementary Figures 1 - 7, Table 1 from A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells
Supplementary Figures 1 - 7, Table 1 from A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells Open
PDF file - 1137K, Supplementary Figure 1: Tropomyosin siRNA knockdown is isoform specific and does not result in any compensation. Supplementary Figure 2: TR100 nullifies the impact of Tm5NM1 on actin filament depolymerization kinetics. Su…
View article: Supplementary Methods from A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells
Supplementary Methods from A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells Open
PDF file - 129K, Supplementary Experimental Methods: Animal studies: Detailed methods outlining the in vivo TR100 animal studies. Tropomyosin compound modeling: Detailed method outlining the in silico modeling of Tm5NM1.
View article: Supplementary Figures 1 - 7, Table 1 from A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells
Supplementary Figures 1 - 7, Table 1 from A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells Open
PDF file - 1137K, Supplementary Figure 1: Tropomyosin siRNA knockdown is isoform specific and does not result in any compensation. Supplementary Figure 2: TR100 nullifies the impact of Tm5NM1 on actin filament depolymerization kinetics. Su…
View article: Supplementary Methods from A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells
Supplementary Methods from A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells Open
PDF file - 129K, Supplementary Experimental Methods: Animal studies: Detailed methods outlining the in vivo TR100 animal studies. Tropomyosin compound modeling: Detailed method outlining the in silico modeling of Tm5NM1.
View article: Data from A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells
Data from A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells Open
The actin cytoskeleton is a potentially vulnerable property of cancer cells, yet chemotherapeutic targeting attempts have been hampered by unacceptable toxicity. In this study, we have shown that it is possible to disrupt specific actin fi…
View article: A Review of Recent Trends in Quantum Thermodynamics and a System’s Behavioural Analysis of the Universe Originating as a Quantum Energy System
A Review of Recent Trends in Quantum Thermodynamics and a System’s Behavioural Analysis of the Universe Originating as a Quantum Energy System Open
This paper combines a review of recent advances in quantum thermodynamics, including work on objective collapse (Zurek’s quantum Darwinism) and quantum gravity (Verlinde’s quantum gravity explanation), with a redefinition of entropy genera…
View article: Hyperpolarized <sup>129</sup>Xe MRI in the Imaging of Chronic Lung Allograft Dysfunction
Hyperpolarized <sup>129</sup>Xe MRI in the Imaging of Chronic Lung Allograft Dysfunction Open
Conclusions: This initial study indicates that 129 Xe MRI can be applied to chronic rejection and detects functional defects in both ventilation and RBC transfer in CLAD patients. 129Xe MRI may have a role in early detection of CLAD and sh…
View article: Syntaxins 6 and 8 facilitate tau into secretory pathways
Syntaxins 6 and 8 facilitate tau into secretory pathways Open
Tau pathology initiates in defined brain regions and is known to spread along neuronal connections as symptoms progress in Alzheimer's disease (AD) and other tauopathies. This spread requires the release of tau from donor cells, but the un…
View article: COVID-19 vaccine attitudes among healthcare workers in New York City: Preliminary findings from the Antibody Response Monitoring for Occupational Resilience (ARMOR) study
COVID-19 vaccine attitudes among healthcare workers in New York City: Preliminary findings from the Antibody Response Monitoring for Occupational Resilience (ARMOR) study Open
View article: RNA-Seq analysis of Gtf2ird1 knockout epidermal tissue provides potential insights into molecular mechanisms underpinning Williams-Beuren syndrome
RNA-Seq analysis of Gtf2ird1 knockout epidermal tissue provides potential insights into molecular mechanisms underpinning Williams-Beuren syndrome Open
Gtf2ird1 inactivation results in widespread gene dysregulation, some of which may be due to the secondary consequences of gene regulatory network disruptions involving several transcription factors and signalling molecules. Genes involved …