James W. Maas
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View article: Adaptor protein-3 produces synaptic vesicles that release phasic dopamine
Adaptor protein-3 produces synaptic vesicles that release phasic dopamine Open
The burst firing of midbrain dopamine neurons releases a phasic dopamine signal that mediates reinforcement learning. At many synapses, however, high firing rates deplete synaptic vesicles (SVs), resulting in synaptic depression that limit…
View article: Adaptor Protein-3 Produces Synaptic Vesicles that Release Phasic Dopamine
Adaptor Protein-3 Produces Synaptic Vesicles that Release Phasic Dopamine Open
The burst firing of midbrain dopamine neurons releases a phasic dopamine signal that mediates reinforcement learning. At many synapses, however, high firing rates deplete synaptic vesicles (SVs), resulting in synaptic depression that limit…
Endogenous Leucine-Rich Repeat Kinase 2 Slows Synaptic Vesicle Recycling in Striatal Neurons Open
Dominant mutations in leucine-rich repeat kinase 2 (LRRK2) produce the most common inherited form of Parkinson's disease (PD) but the function of LRRK2 remains poorly understood. The presynaptic role of multiple genes linked to PD includin…