Jamie V. Shiah
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View article: Transcription Factors and Cancer
Transcription Factors and Cancer Open
Cancer is defined by the presence of uncontrollable cell growth, whereby improper proliferative signaling has overcome regulation by cellular mechanisms. Transcription factors are uniquely situated at the helm of signaling, merging extrace…
View article: Reconstitution reveals friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1
Reconstitution reveals friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1 Open
The endosomal sorting complexes required for transport (ESCRT) system is an ancient and ubiquitous membrane scission machinery that catalyzes the budding and scission of membranes. ESCRT-mediated scission events, exemplified by those invol…