Jamie Willows
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View article: Use of Terlipressin in AKI Associated with Hepatorenal Syndrome: CON
Use of Terlipressin in AKI Associated with Hepatorenal Syndrome: CON Open
1Renal Services, Sunderland Royal Hospital, Sunderland, England 2Department of Medicine, University of Ottawa and the Ottawa Hospital, Ottawa, Canada aAddress for correspondence Swapnil Hiremath 1967 Riverside Drive Ottawa, ON, Canada K1H7…
View article: Remove the “Strict” From “Restriction”: A #NephJC Editorial on SODIUM-HF
Remove the “Strict” From “Restriction”: A #NephJC Editorial on SODIUM-HF Open
#NephJC is a recurring twitter-based journal club. #NephJC editorials highlight the discussed article and summarize key points from the NephJC TweetChat. #NephJC is a recurring twitter-based journal club. #NephJC editorials highlight the d…
View article: Plasma Exchange in Patients With ANCA-Associated Vasculitis: A #NephJC Editorial on a comPLEX Question
Plasma Exchange in Patients With ANCA-Associated Vasculitis: A #NephJC Editorial on a comPLEX Question Open
#NephJC is a recurring twitter-based journal club. #NephJC editorials highlight the discussed article and summarize key points from the NephJC TweetChat.Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a devastatin…
View article: CONFIRMing Hepatorenal Syndrome Management: #NephJC Editorial
CONFIRMing Hepatorenal Syndrome Management: #NephJC Editorial Open
#NephJC is a recurring twitter-based journal club. #NephJC Editorials highlight the discussed article and summarize key points from the NephJC TweetChat. #NephJC is a recurring twitter-based journal club. #NephJC Editorials highlight the d…
View article: The role of complement in kidney disease
The role of complement in kidney disease Open
While the complement cascade is an important component of the innate immune system, uncontrolled activation can cause severe disease. This concept is illustrated by the prototypical complement-mediated renal disease atypical haemolytic ura…
View article: Acute interstitial nephritis due to sodium-glucose co-transporter 2 inhibitor empagliflozin
Acute interstitial nephritis due to sodium-glucose co-transporter 2 inhibitor empagliflozin Open
Biopsy-proven acute interstitial nephritis (AIN) secondary to sodium-glucose co-transporter 2 (SGLT2) inhibitors has not been described previously. Here, we report on the management of a patient with severe acute kidney injury that develop…
View article: Case Report: Investigation and molecular genetic diagnosis of familial hypomagnesaemia
Case Report: Investigation and molecular genetic diagnosis of familial hypomagnesaemia Open
Genetic mutations causing familial hypomagnesaemia syndromes are well-recognised. Affected patients can present with severe symptoms of hypomagnesaemia, such as seizures or cardiac arrhythmia. We report an affected child, from a consanguin…
View article: The challenges of diagnosis and management of Gitelman syndrome
The challenges of diagnosis and management of Gitelman syndrome Open
Gitelman syndrome is an inherited tubulopathy characterized by renal salt wasting from the distal convoluted tubule. Defects in the sodium chloride cotransporter (encoded by SLC12A3 ) underlie this autosomal recessive condition. This artic…
View article: Acquired C1-inhibitor deficiency presenting with nephrotic syndrome
Acquired C1-inhibitor deficiency presenting with nephrotic syndrome Open
Acquired C1-inhibitor (C1-INH) deficiency is a rare and potentially life-threatening disorder, which presents with recurrent attacks of non-pitting oedema to the face, airway, limbs or gastrointestinal tract. It is often associated with un…
View article: Case Report: Investigation and molecular genetic diagnosis of familial hypomagnesaemia: a case report
Case Report: Investigation and molecular genetic diagnosis of familial hypomagnesaemia: a case report Open
Genetic mutations causing familial hypomagnesaemia syndromes are well-recognised. Affected patients can present with severe symptoms of hypomagnesaemia, such as seizures or cardiac arrhythmia. We report an affected child, from a consanguin…
View article: Supplementary Material for: Changing Protein Permeability with Nephron Loss: Evidence for a Human Remnant Nephron Effect
Supplementary Material for: Changing Protein Permeability with Nephron Loss: Evidence for a Human Remnant Nephron Effect Open
Background: If loss of functioning nephrons predisposes to glomerular barotrauma (a “remnant nephron” effect), then glomerular permeability should increase as glomerular filtration rate (GFR) falls, as is observed in animal models of nephr…
View article: CYP24A1 mutations and hypervitaminosis D
CYP24A1 mutations and hypervitaminosis D Open
Editor – We read with interest the case report entitled 'Risks of the 'Sunshine pill' – a case of hypervitaminosis D'.[1][1] We wish to congratulate the authors on reporting this remarkable case, and hoped to make some additional contribut…