Explanipedia

Utilizing Balance Assessment Tools by Physical Therapists for Patients with Balance Disorders Open

Abdulaziz A. Albalwi, Ahmad A. Alharbi, Hamad S. Al Amer, Samia Alamrani, Hani Albalawi , et al. · 2025

Background/Objectives: Physical therapists’ use of various balance assessment tools is essential for accurately identifying deficits and guiding rehabilitation plans. This study aimed to investigate clinical balance assessment practices in…

Identification of Interactive Genetic Loci Linked to Insulin Resistance in Metabolic Syndrome—An Update Open

Imadeldin Elfaki, Rashid Mir, Mohamed E. Elnageeb, Abdullah Hamadi, Zeyad M. Alharbi , et al. · 2025

Metabolic syndrome is a metabolic disorder characterized by hypertension, dyslipidemia, impaired glucose tolerance, and abdominal obesity. Impaired insulin action or insulin resistance initiates metabolic syndrome. The prevalence of insuli…

Molecular Characterization and Impact of the Genetic Variants GSTP1, LncRNA H19, TCF7L2 and HNF1A on the Risk of Coronary Artery Disease With and Without T2DM Comorbidity: A Genomic Biomarker Study Open

Pradeep Kumar Dabla, Rashid Mir, Mohammad Fahad Ullah, Vimal Mehta, Jamsheed Javid , et al. · 2025

The data from the current study have identified certain genetic variants of interest in the given population as risk markers of CAD with and without T2DM comorbidity.

Differential Expression of Serum Proinflammatory Cytokine TNF-α and Genetic Determinants of TNF-α, CYP2C19*17, miR-423 Genes and Their Effect on Coronary Artery Disease Predisposition and Progression Open

Rehab Al-Massabi, Rashid Mir, Jamsheed Javid, Faisel M. Abuduhier, Reema Almotairi , et al. · 2023

Coronary artery disease (CAD) is the leading cause of death and hospitalization worldwide and represents a problem for public health systems everywhere. In Saudi Arabia, the prevalence of CAD is estimated to be 5.5%. Risk factors for CAD i…

Genetic Determinants of Cardiovascular Disease: The Endothelial Nitric Oxide Synthase 3 (eNOS3), Krüppel-Like Factor-14 (KLF-14), Methylenetetrahydrofolate Reductase (MTHFR), MiRNAs27a and Their Association with the Predisposition and Susceptibility to Coronary Artery Disease Open

Rashid Mir, Imadeldin Elfaki, Jamsheed Javid, Jameel Barnawi, Malik A. Altayar , et al. · 2022

Coronary artery disease (CAD) is an important cause of death worldwide. CAD is caused by genetic and other factors including hypertension, hyperlipidemia, obesity, stress, unhealthy diet, physical inactively, smoking and Type 2 diabetes (T…

Clinical Utility of Amplification Refractory Mutation System-Based PCR and Mutation-Specific PCR for Precise and Rapid Genotyping of Angiotensin-Converting Enzyme 1 (ACE1-rs4646996 D>I) and Angiotensin-Converting Enzyme 2 (ACE2-rs4240157T>C) Gene Variations in Coronary Artery Disease and Their Strong Association with Its Disease Susceptibility and Progression Open

Aadil Yousif, Rashid Mir, Jamsheed Javid, Jameel Barnawi, Mohammed M. Jalal , et al. · 2022

Background: Experimental clinical and research studies demonstrated that the renin–angiotensin system (RAS) affects the pathogenesis of atherosclerosis and the prognosis of coronary heart disease (CHD). The results show that ACE2 (angioten…

Reply to Comment: Evaluation of the Association of Omentin 1 rs2274907 A > T and rs2274908 G > A Gene Polymorphisms with Coronary Artery Disease in Indian Population: A Case–Control Study Open

Chandan Kumar Jha, Rashid Mir, Imadeldin Elfaki, Jamsheed Javid, Abdullatif Taha Babakr , et al. · 2020

Coronary artery disease (CAD) is a major cause of death all over the world. CAD is caused by atherosclerosis which is induced by the interaction of genetic factors and environmental factors. Genome-wide association studies have revealed th…

Evaluation of the Association of Omentin 1 rs2274907 A>T and rs2274908 G>A Gene Polymorphisms with Coronary Artery Disease in Indian Population: A Case Control Study Open

Chandan Kumar Jha, Rashid Mir, Imadeldin Elfaki, Jamsheed Javid, Abdullatif Taha Babakr , et al. · 2019

Coronary artery disease (CAD) is a major cause of death all over the world. CAD is caused by atherosclerosis which is induced by the interaction of genetic factors and environmental factors. Traditional environmental risk factors include h…

MicroRNA-146a Gene Polymorphism is Associated with an Increased Susceptibility to Lung Cancer Disease: A Case-control Study Open

Jamsheed Javid, Rashid Mir, Faisel M. Abuduhier · 2019

Potential Impact of COMT-rs4680 G > A Gene Polymorphism in Coronary Artery Disease Open

Rashid Mir, Musadiq A. Bhat, Jamsheed Javid, Chandan Kumar Jha, Alpana Saxena , et al. · 2018

Purpose: Catechol-O-methyltransferase (COMT) plays a central role in DNA repair and estrogen-induced carcinogenesis. The nonsynonymous single nucleotide polymorphism (SNP) in exon 4 G > A or Val108 > 158Met or rs4680 G > A influences COMT …

Optimization of allele specific PCR (AS-PCR) for the early detection of FLT3 (D835Y) mutation in Acute Myeloid Leukemia patients at Tabuk, Saudi Arabia. Open

FM Abu-Duhier, Rashid Mir, Jamsheed Javid, Fawzia. Sharaf., Nabil. Burrow. · 2017

20Jan 2017 Optimization of allele specific PCR (AS-PCR) for the early detection of FLT3 (D835Y) mutation in Acute Myeloid Leukemia patients at Tabuk, Saudi Arabia. Abu-Duhier FM , Rashid Mir , Jamsheed Javid , Fawzia Sharaf and Nabil Burro…

Detection of HER2 polymorphism and expression using circulating DNA and RNA as a tool in lung adenocarcinoma patients: a case control study Open

Rashid Mir, Jamsheed Javid, Prasant Yadav, Anant Mohan, Prakash Chandra Ray , et al. · 2016

Our work provides evidence that circulating DNA and RNA may be a potential prognostic tool in Lung adenocarcinoma patients. Promoter polymorphism of HER2 (-3444C/T) gene had significant impact on higher HER2 mRNA expression could be a pred…

The C609T (Pro187Ser) Null Polymorphism of the NQO1 Gene Contributes Significantly to Breast Cancer Susceptibility in North Indian Populations: a Case Control Study Open

Prasant Yadav, Rashid Mir, Kajal Nandi, Jamsheed Javid, Mirza Masroor , et al. · 2016

The present study shows a strong association between NQO1 C609T polymorphism with the breast cancer risk in the north Indian breast cancer patients so that possible use as a risk factor should be further explored.

Clinical implications of cytosine deletion of exon 5 of P53 gene in non small cell lung cancer patients Open

Rashid Mir, Rashid Mir, Jamsheed Javid, Imtiyaz Ahamad, Shazia Farooq , et al. · 2016

Aim: Lung cancer is considered to be the most common cancer in the world. In humans, about 50% or more cancers have a mutated tumor suppressor p53 gene thereby resulting in accumulation of p53 protein and losing its function to activate th…

Clinical Significance of the NQO1 C609T Polymorphism in Non Small Cell Lung Adenocarcinoma Patients Open

Rashid Mir, Amit Jain, Jamsheed Javid, Rashid Mir, Y Prashant , et al. · 2015

The present study revealed that NQO1 CT, TT and CT+TT genotypes may be associated with clinical outcome and risk of developing NSCLC in the Indian population.

Clinical Implication of EGF A61G Polymorphism in the Risk of Non Small Cell Lung Adenocarcinoma Patients: A Case Control Study Open

Rashid Mir, Jain Amit, Jamsheed Javid, Rashid Mir, Y Prasant , et al. · 2015

The present study revealed that the EGF A61G genotype may be a novel independent prognostic marker to identify patients at higher risk of occurrence and an unfavourable clinical outcome.

Cell Free EGFR mRNA Expression and Implications for Survival and Metastasis in Non-Small Cell Lung Cancer Cases Open

Rashid Mir, Rashid Mir, Jamsheed Javid, Y Prasant, A Imtiyaz , et al. · 2015

Higher cell free EGFR mRNA expression may play an important role in causing distant metastases and reducing overall survival of NSCLC patients in the Indian population.

BAX G(-248)A Gene Polymorphism and Its Association with Risk of Non-Small Cell Lung Cancer—A Case Control Study Open

Jamsheed Javid, Rashid Mir, Pramod Kumar Julka, Prakash Chandra Ray, Alpana Saxena · 2015

Pro-apoptotic Bcl-2 protein BAX is an important member of mitochondrial dependent apoptosis regulation and ultimately plays a pivotal role in malignancies. A promoter G(-248)A polymorphism in the TP53 binding region of BAX results in diffe…

Polymorphism T81C in H-RAS Oncogene Is Associated With Disease Progression in Imatinib (TKI) Treated Chronic Myeloid Leukemia Patients Open

Rashid Mir, Imtiyaz Ah, Jamsheed Javid, Mariyam Zuberi, Sameer Ahmad Guru , et al. · 2015

H-RAS T81C polymorphism was found to be associated with CML risk and prognosis of CML. These results suggest that C heterozygosis may be considered a potential risk factor for CML development in the North Indian population.

Jamsheed Javid YOU? Author Swipe