Jan Åhlén
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View article: Psychosomatic complaints at age 15-16 and later educational achievement in upper secondary school
Psychosomatic complaints at age 15-16 and later educational achievement in upper secondary school Open
Background Psychosomatic complaints are common among adolescents, and the reporting has increased in recent decades. Yet, knowledge on the potential consequences of such complaints is scarce. Given the importance of educational success for…
View article: Educational attainment and symptoms of anxiety and depression in young adulthood
Educational attainment and symptoms of anxiety and depression in young adulthood Open
Background Young adulthood is a life phase when mental health problems are common. Although education is known to exert an influence on health, increased knowledge about the links between educational attainment and mental health problems i…
View article: Self-reported strengths and difficulties among Swedish adolescents: presence, continuity and change
Self-reported strengths and difficulties among Swedish adolescents: presence, continuity and change Open
Background The Strengths and Difficulties Questionnaire (SDQ) is a screening instrument for emotional and behavioural problems. Swedish reference values based on large-scale national data are lacking for mid- and late adolescents. Also, th…
View article: The role of neoadjuvant imatinib in gastrointestinal stromal tumor patients: 20 years of experience from a tertial referral center
The role of neoadjuvant imatinib in gastrointestinal stromal tumor patients: 20 years of experience from a tertial referral center Open
Surgery is the cornerstone of gastrointestinal stromal tumor (GIST) treatment, and adjuvant therapy with imatinib has improved survival for high‐risk tumors. The use of imatinib preoperatively has been increasing, but efficacy and impact o…
View article: The EU effect and the export of environmental standards to the U.S.
The EU effect and the export of environmental standards to the U.S. Open
In the past twenty years, decisions on global environmental regulations have increasingly originated in Brussels instead of Washington. Many European Union (EU) environmental laws are having effects well beyond the borders of the EU. This …
View article: miR-125a-5p regulation increases phosphorylation of FAK that contributes to imatinib resistance in gastrointestinal stromal tumors
miR-125a-5p regulation increases phosphorylation of FAK that contributes to imatinib resistance in gastrointestinal stromal tumors Open
The use of imatinib mesylate has greatly improved the clinical outcome for gastrointestinal stromal tumor (GIST) patients. However, imatinib resistance is still a major clinical challenge, and the molecular mechanisms are not fully underst…
View article: Wide Surgical Margin Improves the Outcome for Patients with Gastrointestinal Stromal Tumors (GISTs)
Wide Surgical Margin Improves the Outcome for Patients with Gastrointestinal Stromal Tumors (GISTs) Open
Background Surgical resection is still the main treatment for gastrointestinal stromal tumor (GIST), and R0 excision, regardless of surgical margins, is considered sufficient. Methods A cohort of 79 consecutive GIST cases treated at the Ka…