Jan Apelqvist
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View article: The unique multidisciplinarity of diabetes‐related foot disease
The unique multidisciplinarity of diabetes‐related foot disease Open
Few diseases globally require treatment from so many different disciplines as diabetes‐related foot disease. At least 25 different professionals may be involved: casting technicians, dermatologists, diabetes (educator) nurses, diabetologis…
View article: Practical guidelines on the prevention and management of diabetes‐related foot disease (IWGDF 2023 update)
Practical guidelines on the prevention and management of diabetes‐related foot disease (IWGDF 2023 update) Open
Diabetes‐related foot disease results in a major global burden for patients and the healthcare system. The International Working Group on the Diabetic Foot (IWGDF) has been producing evidence‐based guidelines on the prevention and manageme…
View article: Definitions and criteria for diabetes‐related foot disease (IWGDF 2023 update)
Definitions and criteria for diabetes‐related foot disease (IWGDF 2023 update) Open
Multiple disciplines are involved in the management of diabetes‐related foot disease and a common vocabulary is essential for clear communication. Based on the systematic reviews of the literature that form the basis of the International W…
View article: Standards for the development and methodology of the 2023 IWGDF guidelines
Standards for the development and methodology of the 2023 IWGDF guidelines Open
Aims Diabetes‐related foot disease is a major source of patient burden and societal costs. Investing in evidence‐based international guidelines on diabetes‐related foot disease is important to reduce this burden and costs, provided the gui…
View article: Re-Ulceration Is Common in Persons with Diabetes and Healed Foot Ulcer After Participant-Driven Education in Group: A Randomized Controlled Trial
Re-Ulceration Is Common in Persons with Diabetes and Healed Foot Ulcer After Participant-Driven Education in Group: A Randomized Controlled Trial Open
Objective: To compare the number of ulcer-free days during 24 months in persons with diabetes and a healed foot ulcer below the ankle provided with adjusted therapeutic shoes who were given standard information and participated in particip…
View article: Gestational diabetes: changed health beliefs in migrant women from five Asian countries living in Sweden: a prospective qualitative study
Gestational diabetes: changed health beliefs in migrant women from five Asian countries living in Sweden: a prospective qualitative study Open
Aim: The aim of this study was to explore the temporal development of beliefs about health, illness and health care in migrant women with gestational diabetes (GD) born in Asia residing in Sweden, and the influence on health-related behavi…
View article: Evaluation of <scp>LL</scp>‐37 in healing of <scp>hard‐to‐heal</scp> venous leg ulcers: A multicentric prospective randomized <scp>placebo‐controlled</scp> clinical trial
Evaluation of <span>LL</span>‐37 in healing of <span>hard‐to‐heal</span> venous leg ulcers: A multicentric prospective randomized <span>placebo‐controlled</span> clinical trial Open
Many patients with venous leg ulcers do not reach complete healing with compression treatment alone, which is current standard care. This clinical trial HEAL LL‐37 was a phase IIb double‐blind, randomized, placebo‐controlled study, with th…
View article: Contrast-Associated Acute Kidney Injury in Patients with and without Diabetes Mellitus Undergoing Computed Tomography Angiography and Local Thrombolysis for Acute Lower Limb Ischemia
Contrast-Associated Acute Kidney Injury in Patients with and without Diabetes Mellitus Undergoing Computed Tomography Angiography and Local Thrombolysis for Acute Lower Limb Ischemia Open
Purpose Repetitive iodinated contrast media exposure may be harmful for the kidneys. The aim of the present study was to evaluate if patients with diabetes mellitus (DM) undergoing CT angiography (CTA) and local continuous thrombolysis for…
View article: Migrant Middle Eastern women with gestational diabetes seven years after delivery – positive long-term development of beliefs about health and illness shown in follow-up interviews
Migrant Middle Eastern women with gestational diabetes seven years after delivery – positive long-term development of beliefs about health and illness shown in follow-up interviews Open
Aim: No previous studies have been found focusing on the long-term development of beliefs about health, illness and healthcare in migrant women with gestational diabetes mellitus (GDM). The aim of this study was to explore this and the inf…
View article: Healing below the ankle is possible in patients with diabetes mellitus and a forefoot gangrene
Healing below the ankle is possible in patients with diabetes mellitus and a forefoot gangrene Open
Background: Forefoot gangrene in patients with diabetes is a severe form of foot ulcers with risk of progress and major amputation. No large cohort studies have examined clinical characteristics and outcome of forefoot gangrene in patients…
View article: Elderly individuals with diabetes and foot ulcer have a probability for healing despite extensive comorbidity and dependency
Elderly individuals with diabetes and foot ulcer have a probability for healing despite extensive comorbidity and dependency Open
Healing without major amputation was achieved in 84% of surviving patients ≥75 years, despite extensive comorbidity and dependency.
View article: Guidelines on use of interventions to enhance healing of chronic foot ulcers in diabetes (IWGDF 2019 update)
Guidelines on use of interventions to enhance healing of chronic foot ulcers in diabetes (IWGDF 2019 update) Open
The International Working Group on the Diabetic Foot (IWGDF) has published evidence‐based guidelines on the prevention and management of diabetic foot disease since 1999. In conjunction with advice from internal and external reviewers and …
View article: Effectiveness of bedside investigations to diagnose peripheral artery disease among people with diabetes mellitus: A systematic review
Effectiveness of bedside investigations to diagnose peripheral artery disease among people with diabetes mellitus: A systematic review Open
The accurate identification of peripheral artery disease (PAD) in patients with diabetes and foot ulceration is important, in order to inform timely management and to plan intervention including revascularisation. A variety of non‐invasive…
View article: Practical Guidelines on the prevention and management of diabetic foot disease (IWGDF 2019 update)
Practical Guidelines on the prevention and management of diabetic foot disease (IWGDF 2019 update) Open
Diabetic foot disease results in a major global burden for patients and the health care system. The International Working Group on the Diabetic Foot (IWGDF) has been producing evidence‐based guidelines on the prevention and management of d…
View article: Effectiveness of interventions to enhance healing of chronic foot ulcers in diabetes: a systematic review
Effectiveness of interventions to enhance healing of chronic foot ulcers in diabetes: a systematic review Open
The management of diabetic foot ulcers (DFU) remains a challenge, and there is continuing uncertainty concerning optimal approaches to wound healing. The International Working Group of the Diabetic Foot (IWGDF) working group on wound heali…
View article: Performance of prognostic markers in the prediction of wound healing or amputation among patients with foot ulcers in diabetes: A systematic review
Performance of prognostic markers in the prediction of wound healing or amputation among patients with foot ulcers in diabetes: A systematic review Open
Clinical outcomes of patients with diabetes, foot ulceration, and peripheral artery disease (PAD) are difficult to predict. The prediction of important clinical outcomes, such as wound healing and major amputation, would be a valuable tool…
View article: Effectiveness of revascularisation of the ulcerated foot in patients with diabetes and peripheral artery disease: A systematic review
Effectiveness of revascularisation of the ulcerated foot in patients with diabetes and peripheral artery disease: A systematic review Open
In patients with diabetes, foot ulceration and peripheral artery disease (PAD), it is often difficult to determine whether, when and how to revascularise the affected lower extremity. The presence of PAD is a major risk factor for non‐heal…
View article: Guidelines on diagnosis, prognosis, and management of peripheral artery disease in patients with foot ulcers and diabetes (IWGDF 2019 update)
Guidelines on diagnosis, prognosis, and management of peripheral artery disease in patients with foot ulcers and diabetes (IWGDF 2019 update) Open
The International Working Group on the Diabetic Foot (IWGDF) has published evidence‐based guidelines on the prevention and management of diabetic foot disease since 1999. This guideline is on the diagnosis, prognosis, and management of per…
View article: Definitions and criteria for diabetic foot disease
Definitions and criteria for diabetic foot disease Open
Multiple disciplines are involved in the management of diabetic foot disease, and a common vocabulary is essential for clear communication. Based on the systematic reviews of the literature that form the basis of the International Working …
View article: Standards for the development and methodology of the 2019 International Working Group on the Diabetic Foot guidelines
Standards for the development and methodology of the 2019 International Working Group on the Diabetic Foot guidelines Open
Diabetic foot disease is a source of major patient suffering and societal costs. Investing in evidence‐based international guidelines on diabetic foot disease is likely among the most cost‐effective forms of health care expenditure, provid…
View article: Optimal wound closure of diabetic foot ulcers with early initiation of TLC-NOSF treatment: post-hoc analysis of Explorer
Optimal wound closure of diabetic foot ulcers with early initiation of TLC-NOSF treatment: post-hoc analysis of Explorer Open
Objective: In March 2018, the Explorer study, an international, double-blind, randomised controlled trial (RCT), established that adding a TLC-NOSF (UrgoStart Contact, Laboratoires Urgo, France) dressing to good local standard of care (SoC…
View article: Strong association between vibration perception thresholds at low frequencies (4 and 8 Hz), neuropathic symptoms and diabetic foot ulcers
Strong association between vibration perception thresholds at low frequencies (4 and 8 Hz), neuropathic symptoms and diabetic foot ulcers Open
Vibration perception thresholds at low frequencies seem to be a better indicator of the risk of developing diabetic foot ulcers, gait or balance problems or weakness of the foot. The 125 Hz frequency, however, seemed to be impaired earlier…