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View article: Impact of tissue storage time on immunodetection of c-Fos and GAD67 in the rat brain
Impact of tissue storage time on immunodetection of c-Fos and GAD67 in the rat brain Open
These findings underscore that whereas intact brains can be safely stored for prolonged periods at 4°C without compromising antigenicity, brain slices are highly susceptible to storage-induced deterioration - insights important for plannin…
View article: Long‐Term Visual Gist Abstraction Independent of Post‐Encoding Sleep
Long‐Term Visual Gist Abstraction Independent of Post‐Encoding Sleep Open
Current theories of memory processing postulate a slow transformation from episodic to abstract, gist‐like memories. We previously demonstrated that sleep shortly after learning improves gist abstraction in healthy volunteers across a one‐…
View article: The influence of peripheral glucose on sleep brain oscillations
The influence of peripheral glucose on sleep brain oscillations Open
Study Objectives Previous research indicates a coupling of sleep-associated brain activity to peripheral glucose levels, such that ripple activity, a sign of increased hippocampal memory processing, is followed within 10 min by a dip in pe…
View article: Rearing Behavior as Indicator of Spatial Novelty and Memory in Developing Rats
Rearing Behavior as Indicator of Spatial Novelty and Memory in Developing Rats Open
Among the various forms of exploration, rearing—where rodents stand on their hind legs—reflects the animal's processing of spatial information and response to environmental novelty. Here, we investigated the developmental trajectory of rea…
View article: Regulation of peripheral glucose levels during human sleep
Regulation of peripheral glucose levels during human sleep Open
Studies in rats indicate that oscillatory signatures of memory processing during sleep, specifically hippocampal sharp wave-ripples, also regulate peripheral glucose concentration. Here, we examined whether there is a similar link between …
View article: The effect of fasting on human memory consolidation
The effect of fasting on human memory consolidation Open
The consolidation of long-term memory is thought to critically rely on sleep. However, first evidence from a study in Drosophila suggests that hunger, as another brain state, can benefit memory consolidation as well. Here, we report two hu…
View article: Spatiotemporal patterns of theta-band activity during rapid-eye movement sleep: a magnetoencephalography analysis
Spatiotemporal patterns of theta-band activity during rapid-eye movement sleep: a magnetoencephalography analysis Open
Theta oscillations (4-8 Hz) in frontal cortical regions are present to different degrees across states of consciousness. In sleep, theta is prominent in periods of rapid eye-movement (REM) sleep. Theta has been linked to processes of memor…
View article: Long-term memory formation for voices during sleep in three-month-old infants
Long-term memory formation for voices during sleep in three-month-old infants Open
The ability to form long-term memories begins in early infancy. However, little is known about the specific mechanisms that guide memory formation during this developmental stage. We demonstrate the emergence of a long-term memory for a no…
View article: Slow-wave sleep drives sleep-dependent renormalization of synaptic AMPA receptor levels in the hypothalamus
Slow-wave sleep drives sleep-dependent renormalization of synaptic AMPA receptor levels in the hypothalamus Open
According to the synaptic homeostasis hypothesis (SHY), sleep serves to renormalize synaptic connections that have been potentiated during the prior wake phase due to ongoing encoding of information. SHY focuses on glutamatergic synaptic s…
View article: Comparing targeted memory reactivation during slow wave sleep and sleep stage 2
Comparing targeted memory reactivation during slow wave sleep and sleep stage 2 Open
Sleep facilitates declarative memory consolidation, which is assumed to rely on the reactivation of newly encoded memories orchestrated by the temporal interplay of slow oscillations (SO), fast spindles and ripples. SO as well as the numbe…
View article: Sleep shapes the associative structure underlying pattern completion in multielement event memory
Sleep shapes the associative structure underlying pattern completion in multielement event memory Open
Sleep supports the consolidation of episodic memory. It is, however, a matter of ongoing debate how this effect is established, because, so far, it has been demonstrated almost exclusively for simple associations, which lack the complex as…
View article: Odor cueing of declarative memories during sleep enhances coordinated spindles and slow oscillations
Odor cueing of declarative memories during sleep enhances coordinated spindles and slow oscillations Open
Long-term memories are formed by repeated reactivation of newly encoded information during sleep. This process can be enhanced by using memory-associated reminder cues like sounds and odors. While auditory cueing has been researched extens…
View article: The influence of intentions on dream content
The influence of intentions on dream content Open
Study Objectives The “Zeigarnik effect” refers to the phenomenon where future intentions are remembered effectively only as long as they are not executed. This study investigates whether these intentions, which remain active during sleep, …
View article: Development of slow oscillation–spindle coupling from infancy to toddlerhood
Development of slow oscillation–spindle coupling from infancy to toddlerhood Open
Sleep has been demonstrated to support memory formation from early life on. The precise temporal coupling of slow oscillations (SOs) with spindles has been suggested as a mechanism facilitating this consolidation process in thalamocortical…
View article: Optimizing the methodology of human sleep and memory research
Optimizing the methodology of human sleep and memory research Open
Contains fulltext : 315028.pdf (Publisher’s version ) (Open Access)
View article: Targeted memory reactivation is not more effective during slow wave sleep than sleep stage 2
Targeted memory reactivation is not more effective during slow wave sleep than sleep stage 2 Open
Sleep facilitates memory consolidation, which is assumed to rely on the reactivation of newly encoded memories orchestrated by the temporal interplay of slow oscillations (SO), fast spindles and ripples. SO as well as the number of spindle…
View article: Sleep consolidates stimulus–response learning
Sleep consolidates stimulus–response learning Open
Performing a motor response to a sensory stimulus creates a memory trace whose behavioral correlates are classically investigated in terms of repetition priming effects. Such stimulus–response learning entails two types of associations tha…
View article: Human REM sleep recalibrates neural activity in support of memory formation
Human REM sleep recalibrates neural activity in support of memory formation Open
The proposed mechanisms of sleep-dependent memory consolidation involve the overnight regulation of neural activity at both synaptic and whole-network levels. Now, there is a lack of in vivo data in humans elucidating if, and how, sleep an…
View article: Optimizing Methodology of Sleep and Memory Research in Humans
Optimizing Methodology of Sleep and Memory Research in Humans Open
Understanding the complex relationship between sleep and memory is a major challenge in neuroscience. Many studies on memory consolidation in humans suggest that sleep triggers offline memory processes, resulting in less forgetting of decl…