Jan E. Conn
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View article: Submicroscopic infections and two malaria vectors are major contributors to residual malaria in an Amazonian village in Peru
Submicroscopic infections and two malaria vectors are major contributors to residual malaria in an Amazonian village in Peru Open
In the Loreto region of Amazonian Peru, the primary malaria vector is Nyssorhynchus (or Anopheles) darlingi. The present year-long study sought to identify specific landscapes with the greatest risk of Plasmodium transmission, incorporatin…
View article: First detection of Nyssorhynchus rondoniensis (Diptera: Culicidae) in southern Venezuela and its infection with Plasmodium falciparum
First detection of Nyssorhynchus rondoniensis (Diptera: Culicidae) in southern Venezuela and its infection with Plasmodium falciparum Open
Ongoing efforts to control vectors and eliminate malaria in the Neotropics are hampered by challenges that include accurate mosquito identification and acquisition of relevant local ecological data. In Bolivar state, southern Venezuela, 88…
View article: Future global distribution and climatic suitability of Anopheles stephensi
Future global distribution and climatic suitability of Anopheles stephensi Open
Anopheles stephensi , an urban malaria vector, is expanding into new regions and poses a growing global health threat. Using a robust multi-model framework with eight algorithms and high-resolution climate data, this study assessed and map…
View article: Two chromosomal reference genome sequences for the malaria mosquito, Anopheles (Nyssorhynchus) darlingi, Root, 1926 from French Guiana and Peru
Two chromosomal reference genome sequences for the malaria mosquito, Anopheles (Nyssorhynchus) darlingi, Root, 1926 from French Guiana and Peru Open
We present two genome assemblies, each generated from individual female Anopheles (Nyssorhynchus) darlingi (the malaria mosquito; Arthropoda; Insecta; Diptera; Culicidae), from wild populations in French Guiana and Peru. The genome sequenc…
View article: Population genomics of <i>Anopheles darlingi</i>, the principal South American malaria vector mosquito
Population genomics of <i>Anopheles darlingi</i>, the principal South American malaria vector mosquito Open
Malaria in South America remains a serious public health problem. Anopheles ( Nyssorhynchus ) darlingi is the most important malaria vector across tropical Latin America. Vector-targeted disease control efforts require a thorough understan…
View article: Distribution of Anophelinae (Diptera: Culicidae) and challenges for malaria elimination in Brazil
Distribution of Anophelinae (Diptera: Culicidae) and challenges for malaria elimination in Brazil Open
In 1909, Arthur Neiva published an article titled “Contribuição para os estudos dos dipteros. Observação sobre a biolojia e sistematica das anofelinas brasileiras e suas relações com o impaludismo”, highlighting the biology, ecology, and d…
View article: Forest cover percentage drives the peak biting time of Nyssorhynchus darlingi (Diptera: Culicidae) in the Brazilian Amazon
Forest cover percentage drives the peak biting time of Nyssorhynchus darlingi (Diptera: Culicidae) in the Brazilian Amazon Open
Background Deforestation is an important driver of malaria dynamics, with a relevant impact on mosquito ecology, including larval habitat availability, blood-feeding behaviour, and peak biting time. The latter is one of several entomologic…
View article: Effect of spatiotemporal variables on abundance, biting activity and parity of Nyssorhynchus darlingi (Diptera: Culicidae) in peri-Iquitos, Peru
Effect of spatiotemporal variables on abundance, biting activity and parity of Nyssorhynchus darlingi (Diptera: Culicidae) in peri-Iquitos, Peru Open
Background In malaria endemic regions of the Peruvian Amazon, rainfall together with river level and breeding site availability drive fluctuating vector mosquito abundance and human malaria cases, leading to temporal heterogeneity. The mai…
View article: Mutations Linked to Insecticide Resistance Not Detected in the Ace-1 or VGSC Genes in Nyssorhynchus darlingi from Multiple Localities in Amazonian Brazil and Peru
Mutations Linked to Insecticide Resistance Not Detected in the Ace-1 or VGSC Genes in Nyssorhynchus darlingi from Multiple Localities in Amazonian Brazil and Peru Open
Indoor residual spray (IRS), mainly employing pyrethroid insecticides, is the most common intervention for preventing malaria transmission in many regions of Latin America; the use of long-lasting insecticidal nets (LLINs) has been more li…
View article: Mutations Linked to Insecticide Resistance Not Detected in Ace-1 or VGSC Genes in Nyssorhynchus darlingi from Multiple Localities in Amazonian Brazil and Peru
Mutations Linked to Insecticide Resistance Not Detected in Ace-1 or VGSC Genes in Nyssorhynchus darlingi from Multiple Localities in Amazonian Brazil and Peru Open
Indoor residual spray (IRS), mainly employing pyrethroid insecticides, is the most common intervention to prevent malaria transmission in many regions of Latin America; the use of long-lasting insecticidal nets (LLINs) has been more limite…
View article: Natural Infection of Nyssorhynchus darlingi and Nyssorhynchus benarrochi B with Plasmodium during the Dry Season in the Understudied Low-Transmission Setting of Datem del Marañon Province, Amazonian Peru
Natural Infection of Nyssorhynchus darlingi and Nyssorhynchus benarrochi B with Plasmodium during the Dry Season in the Understudied Low-Transmission Setting of Datem del Marañon Province, Amazonian Peru Open
The persistence of malaria hotspots in Datem del Marañon Province, Peru, prompted vector control units at the Ministry of Health, Loreto Department, to collaborate with the Amazonian International Center of Excellence for Malaria Research …
View article: Entomological parameters and population structure at a microgeographic scale of the main Colombian malaria vectors Anopheles albimanus and Anopheles nuneztovari
Entomological parameters and population structure at a microgeographic scale of the main Colombian malaria vectors Anopheles albimanus and Anopheles nuneztovari Open
Population subdivision among several neotropical malaria vectors has been widely evaluated; however, few studies have analyzed population variation at a microgeographic scale, wherein local environmental variables may lead to population di…
View article: Evidence-Based Malaria Control and Elimination in the Amazon: Input from the International Center of Excellence in Malaria Research Network in Peru and Brazil
Evidence-Based Malaria Control and Elimination in the Amazon: Input from the International Center of Excellence in Malaria Research Network in Peru and Brazil Open
Malaria remains endemic in 17 countries in the Americas, where 723,000 cases were reported in 2019. The majority (> 90%) of the regional malaria burden is found within the Amazon Basin, which includes nine countries and territories in Sout…
View article: Malaria Resilience in South America: Epidemiology, Vector Biology, and Immunology Insights from the Amazonian International Center of Excellence in Malaria Research Network in Peru and Brazil
Malaria Resilience in South America: Epidemiology, Vector Biology, and Immunology Insights from the Amazonian International Center of Excellence in Malaria Research Network in Peru and Brazil Open
The 1990s saw the rapid reemergence of malaria in Amazonia, where it remains an important public health priority in South America. The Amazonian International Center of Excellence in Malaria Research (ICEMR) was designed to take a multidis…
View article: Insights into Plasmodium vivax Asymptomatic Malaria Infections and Direct Skin-Feeding Assays to Assess Onward Malaria Transmission in the Amazon
Insights into Plasmodium vivax Asymptomatic Malaria Infections and Direct Skin-Feeding Assays to Assess Onward Malaria Transmission in the Amazon Open
Understanding the reservoir and infectivity of Plasmodium gametocytes to vector mosquitoes is crucial to align strategies aimed at malaria transmission elimination. Yet, experimental information is scarce regarding the infectivity of Plasm…
View article: Molecular Analysis Reveals a High Diversity of Anopheline Mosquitoes in Yanomami Lands and the Pantanal Region of Brazil
Molecular Analysis Reveals a High Diversity of Anopheline Mosquitoes in Yanomami Lands and the Pantanal Region of Brazil Open
Identifying the species of the subfamily Anophelinae that are Plasmodium vectors is important to vector and malaria control. Despite the increase in cases, vector mosquitoes remain poorly known in Brazilian indigenous communities. This stu…
View article: Susceptibility of Field-Collected Nyssorhynchus darlingi to Plasmodium spp. in Western Amazonian Brazil
Susceptibility of Field-Collected Nyssorhynchus darlingi to Plasmodium spp. in Western Amazonian Brazil Open
Mosquito susceptibility to Plasmodium spp. infection is of paramount importance for malaria occurrence and sustainable transmission. Therefore, understanding the genetic features underlying the mechanisms of susceptibility traits is pivota…
View article: Ecology and larval population dynamics of the primary malaria vector Nyssorhynchus darlingi in a high transmission setting dominated by fish farming in western Amazonian Brazil
Ecology and larval population dynamics of the primary malaria vector Nyssorhynchus darlingi in a high transmission setting dominated by fish farming in western Amazonian Brazil Open
Vale do Rio Juruá in western Acre, Brazil, is a persistent malaria transmission hotspot partly due to fish farming development that was encouraged to improve local standards of living. Fish ponds can be productive breeding sites for Amazon…
View article: New Records of <i>Anopheles benarrochi</i> B (Diptera: Culicidae) in Malaria Hotspots in the Amazon Regions of Ecuador and Peru
New Records of <i>Anopheles benarrochi</i> B (Diptera: Culicidae) in Malaria Hotspots in the Amazon Regions of Ecuador and Peru Open
The increase in malaria transmission in the Amazon region motivated vector control units of the Ministry of Health of Ecuador and Peru to investigate Anopheles (Diptera: Culicidae) species present in transmission hotspots. Mosquitoes were …
View article: Malaria in Southern Venezuela: The hottest hotspot in Latin America
Malaria in Southern Venezuela: The hottest hotspot in Latin America Open
Malaria elimination in Latin America is becoming an elusive goal. Malaria cases reached a historical ~1 million in 2017 and 2018, with Venezuela contributing 53% and 51% of those cases, respectively. Historically, malaria incidence in sout…
View article: Population dynamics of the primary malaria vector<i>Nyssorhynchus darlingi</i>in a high transmission setting dominated by fish farming in western Amazonian Brazil
Population dynamics of the primary malaria vector<i>Nyssorhynchus darlingi</i>in a high transmission setting dominated by fish farming in western Amazonian Brazil Open
Vale do Rio Juruá in western Acre, Brazil, has reported highest malaria numbers since 2005, and is considered persistent transmission hotspot. Fish farming development was encouraged to improve standard of living, resulting in productive b…
View article: Anthropogenic landscape decreases mosquito biodiversity and drives malaria vector proliferation in the Amazon rainforest
Anthropogenic landscape decreases mosquito biodiversity and drives malaria vector proliferation in the Amazon rainforest Open
Inter-relationships among mosquito vectors, Plasmodium parasites, human ecology, and biotic and abiotic factors, drive malaria risk. Specifically, rural landscapes shaped by human activities have a great potential to increase the abundance…
View article: Phylogenetic Network of Mitochondrial <i>COI</i> Gene Sequences Distinguishes 10 Taxa Within the Neotropical Albitarsis Group (Diptera: Culicidae), Confirming the Separate Species Status of <i>Anopheles albitarsis</i> H (Diptera: Culicidae) and Revealing a Novel Lineage, <i>Anopheles albitarsis</i> J
Phylogenetic Network of Mitochondrial <i>COI</i> Gene Sequences Distinguishes 10 Taxa Within the Neotropical Albitarsis Group (Diptera: Culicidae), Confirming the Separate Species Status of <i>Anopheles albitarsis</i> H (Diptera: Culicidae) and Revealing a Novel Lineage, <i>Anopheles albitarsis</i> J Open
The Neotropical Albitarsis Group is a complex assemblage of essentially isomorphic species which currently comprises eight recognized species—five formally described (Anopheles albitarsis Lynch-Arribalzaga, An. deaneorum Rosa-Freitas, An. …
View article: Integrating Parasitological and Entomological Observations to Understand Malaria Transmission in Riverine Villages in the Peruvian Amazon
Integrating Parasitological and Entomological Observations to Understand Malaria Transmission in Riverine Villages in the Peruvian Amazon Open
Background Remote rural riverine villages account for most of the reported malaria cases in the Peruvian Amazon. As transmission decreases due to intensive standard control efforts, malaria strategies in these villages will need to be more…