Jan Feldheim
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View article: Roles of beta synchronisation for motor skill acquisition change after stroke
Roles of beta synchronisation for motor skill acquisition change after stroke Open
Beta event-related synchronisation (ERS) following movement has been associated with motor skill acquisition in healthy individuals, yet its role in stroke recovery remains unclear. Given the prevalence of motor impairments after stroke, u…
View article: Localized network damage related to white matter hyperintensities is linked to worse outcome after severe stroke
Localized network damage related to white matter hyperintensities is linked to worse outcome after severe stroke Open
White matter hyperintensities of presumed vascular origin (WMH) are associated with various clinical sequelae. In stroke patients, the total WMH burden is linked to recurrent cerebrovascular events and worse clinical outcomes. As WMH also …
View article: Group-derived and individual disconnection in stroke: recovery prediction and deep graph learning
Group-derived and individual disconnection in stroke: recovery prediction and deep graph learning Open
Recent advances in the treatment of acute ischemic stroke contribute to improved patient outcomes, yet the mechanisms driving long-term disease trajectory are not well-understood. Current trends in the literature emphasize the distributed …
View article: Altered Functional Connectivity Between Cortical Premotor Areas and the Spinal Cord in Chronic Stroke
Altered Functional Connectivity Between Cortical Premotor Areas and the Spinal Cord in Chronic Stroke Open
BACKGROUND: Neuroscience research has contributed significantly to understanding alterations in brain structure and function after ischemic stroke. Technical limitations have excluded the spinal cord from imaging-based research. Available …
View article: Human cortical high‐gamma power scales with movement rate in healthy participants and stroke survivors
Human cortical high‐gamma power scales with movement rate in healthy participants and stroke survivors Open
Motor cortical high‐gamma oscillations (60–90 Hz) occur at movement onset and are spatially focused over the contralateral primary motor cortex. Although high‐gamma oscillations are widely recognized for their significance in human motor c…
View article: Cortical microstructure and hemispheric specialization—A diffusion‐imaging analysis in younger and older adults
Cortical microstructure and hemispheric specialization—A diffusion‐imaging analysis in younger and older adults Open
Characterizing cortical plasticity becomes increasingly important for identifying compensatory mechanisms and structural reserve in the ageing population. While cortical thickness (CT) largely contributed to systems neuroscience, it incomp…
View article: A lesion‐aware automated processing framework for clinical stroke magnetic resonance imaging
A lesion‐aware automated processing framework for clinical stroke magnetic resonance imaging Open
Magnetic resonance imaging (MRI) and MRI based computational modelling studies provide insights into severity and recovery of ischemic stroke patients. The presence of brain lesions, however, can heavily distort and impair state‐of‐the‐art…
View article: Altered functional connectivity between cortical premotor areas and the spinal cord in chronic stroke
Altered functional connectivity between cortical premotor areas and the spinal cord in chronic stroke Open
Background Neuroscience research has contributed significantly to understanding alterations in brain structure and function after ischemic stroke. Technical limitations have excluded the spinal cord from imaging-based research. Available d…
View article: Assessing the cortical microstructure in contralesional sensorimotor areas after stroke
Assessing the cortical microstructure in contralesional sensorimotor areas after stroke Open
Cortical thickness analyses have provided valuable insights into changes in cortical brain structure after stroke and their association with recovery. Across studies though, relationships between cortical structure and function show incons…
View article: Human cortical high-gamma power relates to movement speed and is disproportionately reduced after stroke
Human cortical high-gamma power relates to movement speed and is disproportionately reduced after stroke Open
Motor cortical high-gamma oscillations (60 to 90 Hz) occur at the onset of movement and are spatially focused over the contralateral primary motor cortex. Although high-gamma oscillations are widely recognized for their significance in hum…
View article: Association between activity in the ventral premotor cortex and spinal cord activation during force generation—A combined cortico‐spinal <scp>fMRI</scp> study
Association between activity in the ventral premotor cortex and spinal cord activation during force generation—A combined cortico‐spinal <span>fMRI</span> study Open
Force generation is a crucial element of dexterity and a highly relevant skill of the human motor system. How cerebral and spinal components interact and how spinal activation is associated with the activity in the cerebral primary motor a…
View article: Lesion aware automated processing pipeline for multimodal neuroimaging stroke data and The Virtual Brain (TVB)
Lesion aware automated processing pipeline for multimodal neuroimaging stroke data and The Virtual Brain (TVB) Open
Background Processing stroke magnetic resonance imaging (MRI) brain data can be susceptible to lesion-based abnormalities. In this study we developed and validated the Lesion Aware automated Processing Pipeline (LeAPP) that incorporates mi…
View article: Ventral premotor cortex influences spinal cord activation during force generation
Ventral premotor cortex influences spinal cord activation during force generation Open
Force generation is a crucial element of dexterity and a highly relevant skill of the human motor system. How cerebral and spinal components interact and how spinal activation is influenced by cerebral primary motor and premotor areas is p…
View article: Retracted and Replaced: Altered microstructure of the contralesional ventral premotor cortex and motor output after stroke
Retracted and Replaced: Altered microstructure of the contralesional ventral premotor cortex and motor output after stroke Open
This article has been retracted and replaced. Please see https://doi.org/10.1093/braincomms/fcae149 for details. The replacement article can be found at https://doi.org/10.1093/braincomms/fcae115
View article: Brain network topology early after stroke relates to recovery
Brain network topology early after stroke relates to recovery Open
Analyses of alterations of brain networks have gained an increasing interest in stroke rehabilitation research. Compared with functional networks derived from resting-state analyses, there is limited knowledge of how structural network top…
View article: Crossmodal Pattern Discrimination in Humans and Robots: A Visuo-Tactile Case Study
Crossmodal Pattern Discrimination in Humans and Robots: A Visuo-Tactile Case Study Open
The quality of crossmodal perception hinges on two factors: The accuracy of the independent unimodal perception and the ability to integrate information from different sensory systems. In humans, the ability for cognitively demanding cross…
View article: Issue Information
Issue Information Open
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View article: Low‐Frequency Brain Oscillations Track Motor Recovery in Human Stroke
Low‐Frequency Brain Oscillations Track Motor Recovery in Human Stroke Open
Objective The majority of patients with stroke survive the acute episode and live with enduring disability. Effective therapies to support recovery of motor function after stroke are yet to be developed. Key to this development is the iden…
View article: Crossmodal Pattern Discrimination in Humans and Robots: A Visuo-Tactile Case Study
Crossmodal Pattern Discrimination in Humans and Robots: A Visuo-Tactile Case Study Open
The quality of crossmodal perception hinges on two factors: The accuracy of the independent unimodal perception and the ability to integrate information from different sensory systems. In humans, the ability for cognitively demanding cross…
View article: Effects of transcranial alternating-current stimulation to secondary motor areas on cortical oscillations in stroke patients
Effects of transcranial alternating-current stimulation to secondary motor areas on cortical oscillations in stroke patients Open
Background There is growing evidence that secondary motor areas are relevant for recovery after motor stroke. Communication among brain areas occurs via synchronization of oscillatory activity which can potentially be modulated via transcr…
View article: Sensory and auditory evoked responses mimic synchronization of cortical oscillations induced by Transcranial Magnetic Stimulation
Sensory and auditory evoked responses mimic synchronization of cortical oscillations induced by Transcranial Magnetic Stimulation Open
Background Entrainment of cortical oscillations by repetitive Transcranial Magnetic Stimulation (rTMS) is an attractive approach to modulate brain function non-invasively in humans. Here, we applied rTMS in order to modulate oscillatory ac…
View article: Cortico-Cerebellar Structural Connectivity Is Related to Residual Motor Output in Chronic Stroke
Cortico-Cerebellar Structural Connectivity Is Related to Residual Motor Output in Chronic Stroke Open
Functional imaging studies have argued that interactions between cortical motor areas and the cerebellum are relevant for motor output and recovery processes after stroke. However, the impact of the underlying structural connections is poo…
View article: Evolution of brain activation after stroke in a constant-effort versus constant-output motor task
Evolution of brain activation after stroke in a constant-effort versus constant-output motor task Open
We conclude that initial up-regulation of brain activity after stroke is not simply a consequence of enhanced effort early after stroke but rather reflects neural processes involved in reorganisation and recovery of function.